Efficacy and safety of CalliSpheres drug-eluting beads for bronchial arterial chemoembolization for refractory non-small-cell lung cancer and its impact on quality of life: A multi... by Yu Wei Zhao, Song Liu, Hao Qin, Jin Bo Sun, Mao Su, Guang Ji Yu, Jun Zhou, Fei Gao, Ruo Yu Wang, Tong Zhao, Guang Sheng Zhao

“…The main adverse reaction after DEB-BACE was chest pain (13/43, grade 1) followed by fever (10/43, grade 1–2), which was significantly relieved within 3–5 days after symptomatic treatment. …”
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Association between glycated hemoglobin (HbA1c) level and cardiac perfusion and function on gated myocardial perfusion SPECT by Hatem Nasr, Hoda Alsomali, Ibrahim Saad, Asmaa AbdElaal, Nsreen Mohamadien

“…Patients with HbA1c% > 6.5 compared to ≤ 6.5%, had lower LVEF% of 53.17 ± 14.55 vs. 57.8 ± 12.61 (p = 0.017), lower HDL of 1.046 ± 0.262 vs. 1.196 ± 0.295 (p < 0.001), more LVEF < 50% (30% vs. 15.6%; p = 0.017), ESV > 44 ml (38.2% vs. 20%; p = 0.005), and WMA (24.5% vs. 12.2%; p = 0.027), hypertension (77.3% vs. 54.4%; p = 0.001) and dyspnea (27.3% vs. 15.6%; p = 0.047), however, with less chest pain (70.9% vs. 83.3%; p = 0.039). Diabetic patients with HbA1c% > 7.5 had lower LVEF% (52.0 ± 14.59 vs. 57.6 ± 11.55; p = 0.018) and HDL (1.005 ± 0.239 vs 1.148 ± 0.273; p < 0.002), more LVEF < 50% (33.3% vs. 14.5%; p = 0.011), ESV > 44 ml (41.3% vs. 20.3%; p = 0.009), WMA (30.2% vs. 11.6%; p = 0.008), and EDV > 100 ml (34.9% vs. 18.8%; p = 0.037). …”
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An international, stepped wedge, cluster-randomized trial investigating the 0/1-h algorithm in suspected acute coronary syndrome in Asia: the rational of the DROP-Asian ACS study by Kenji Inoue, Jack Tan Wei Chieh, Lim Chiw Yeh, Shuo-Ju Chiang, Arintaya Phrommintikul, Pannipa Suwanasom, Sazzli Kasim, Bakhtiar Ahmad, Alzamani Mohammad Idrose, Farina Mohd Salleh, Shunsuke Oyamada, Yohei Hirano, Shohei Ouchi, Moriyuki Terakura, Naoyuki Yokoyama, Ken Kozuma, Mamoru Nanasato, Ryosuke Higuchi, Kazuhiko Yumoto, Tomoyuki Fukuzawa, Issei Shimada, Evangelos Giannitsis, Raphael Twerenbold, Tohru Minamino

“…Methods The DROP-Asian ACS is a prospective, stepped wedge, cluster-randomized trial enrolling 4260 participants presenting with chest pain to the ED of 12 acute care hospitals in five Asian countries (UMIN; 000042461). …”
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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study by Lane, JCE, Weaver, J, Kostka, K, Burn, E, Kolovos, S, Prats-Uribe, A, Xie, J, Newby, D, Prieto-Alhambra, D, OHDSI-COVID-19 consortium

“…Addition of azithromycin appeared to be associated with an increased risk of 30-day cardiovascular mortality (calibrated HR 2·19 [95% CI 1·22–3·95]), chest pain or angina (1·15 [1·05–1·26]), and heart failure (1·22 [1·02–1·45]).…”

Esophageal variceal ligation plus sclerotherapy vs. ligation alone for the treatment of esophageal varices by Xiaofen Yue, Xiaofen Yue, Zeyu Wang, Jianbiao Li, Xiaoling Guo, Xiehua Zhang, Shengnan Li, Shengnan Li, Hongcheng Lv, Dongsheng Hu, Xiangjun Ji, Shuang Li, Wei Lu

“…The adverse events (fever, chest pain, swallowing, and esophageal stricture) showed no significant difference between the two groups (P &gt; 0.05). …”
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Patterns and Outcomes of Obesity Using Body Mass Index in Patients Hospitalized with Acute Cardiovascular Disorders: A Retrospective Analysis of 7284 Patients in a Middle Eastern C... by Abdul Rehman Abid, Ayman El-Menyar, Rajvir Singh, Mohamed Gomaa, Said Habib, Ahmed Shaaban Abdelrahman, Nidal Asaad, Awad AlQahtani, Hassan Al-Thani, Hajar AlBinali, Jassim Al Suwaidi

“…Diabetes mellitus (DM), hypertension, and dyslipidemia were more common in Group III. Chest pain was more common in Group II, while shortness of breath was more evident in Group III (<i>p</i> < 0.001). …”
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Efficacy and safety of Lianhua Qingwen granule in the treatment of non-influenza viral pneumonia: a randomized, double-blind, placebo-controlled, multicenter clinical study by Chengjie Ma, Bojun Chen, Yanming Li, Li Gu, Jianping Dong, Zhenyang Xu, Lijuan Wei, Zhihong He, Xiuhong Nie, Shuwen Feng, Bin Cao, Lei Sun, Limin Yang, Xingwang Li, Rongmeng Jiang

“…There were no statistical differences in fever, sputum color change, chest pain, muscle pain, dyspnea, chills, and thirst between the two groups (p &gt; 0.05).SafetyThere were no significant differences in body weight, vital signs, blood routine, urine routine, stool routine, and blood biochemical indicators (CK, AST, ALT, Cr, and Bun) between the two groups before and after treatment (p &gt; 0.05). …”
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Coronary fistula between left anterior descendent artery and pulmonary artery: Case report with literature review by Rafael Figueroa-Casanova, Juan D. Saavedra-Henao, Monica B. Mosos-Patiño, Nicolas Lozano-Suarez, Diego A. Beltran-Rincon, Carlos J. Perez-Rivera

“…Their clinical presentation is commonly asymptomatic, and is mainly found as an incidental diagnosis in coronary angiography or coronary angioTAC.We report a young adult without comorbidities who presented with chest pain. Biomarker elevation was confirmed, and acute coronary syndrome was suspected. …”
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Predictive Effect of Triglyceride-Glucose Index on Adverse Prognostic Events in Patients with Type 2 Diabetes Mellitus and Ischemic Cardiomyopathy by Abuduaini B, Yang L, Jiamali N, Seyiti Z, Shan XF, Gao XM

“…The TyG index was calculated using the [fasting triglycerides (mg/dL) × fasting plasma glucose (mg/dL)/2] equation.Results: After adjusting for age, BMI, and other potential confounders, the scores of multivariate Cox proportional hazards regression models for chest pain [9.056 (4.370 to 18.767), p< 0.001], acute myocardial infarction [4.437 (1.420 to 13.869), p=0.010], heart failure [7.334 (3.424 to 15.708), p< 0.001], cardiogenic shock [3.707 (1.207 to 11.384), p=0.022], malignant arrhythmia [5.309 (2.367 to 11.908), p< 0.001], cerebral infarction [3.127 (1.596 to 6.128), p< 0.001], gastrointestinal bleeding [4.326 (1.612 to 11.613), p=0.004], all-cause death [4.502 (3.478 to 5.827), p< 0.001] and cumulative incidence of MACCEs [4.856 (3.842 to 6.136), p< 0.001] increased significantly with an increase in TyG index levels (all p< 0.05). …”
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Clinical impact of cardiac magnetic resonance in patients with suspected coronary artery disease associated with chronic kidney disease (AQUAMARINE-CKD study): study protocol for a... by Teruo Noguchi, Hideki Ota, Naoya Matsumoto, Yoshiaki Morita, Akira Oshita, Eiji Kawasaki, Tomohiro Kawasaki, Kensuke Moriwaki, Shingo Kato, Kazuki Fukui, Tomoya Hoshi, Hiroaki Watabe, Tomoaki Kanaya, Yasuhide Asaumi, Yu Kataoka, Fumiyuki Otsuka, Kensuke Takagi, Shuichi Yoneda, Kenichiro Sawada, Takamasa Iwai, Hideo Matama, Satoshi Honda, Masashi Fujino, Hiroyuki Miura, Kunihiro Nishimura, Kei Takase

“…Abstract Background Although screening for coronary artery disease (CAD) using computed tomography coronary angiography in patients with stable chest pain has been reported to be beneficial, patients with chronic kidney disease (CKD) might have limited benefit due to complications of contrast agent nephropathy and decreased diagnostic accuracy as a result of coronary artery calcifications. …”
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Overruling of Procalcitonin-Guided Antibiotics for Lower Respiratory Tract Infections in Primary Care: Ancillary Study of a Randomized Controlled Trial by José Knüsli, Loïc Lhopitallier, Andreas Kronenberg, Jean-Yves Meuwly, Onya Opota, Marc-Antoine Perrenoud, Marie-Anne Page, Kevin C. Kain, Aline Mamin, Valérie D’Acremont, Nicolas Senn, Yolanda Mueller, Isabella Locatelli, Noémie Boillat-Blanco

“…Factors associated with an overruling of procalcitonin guidance were: a history of chest pain (adjusted OR [aOR] 1.81, 95% confidence interval 1.03–3.17); a prescription of chest X-ray by the GP (aOR 4.65, 2.32–9.34); a C-reactive protein measured retrospectively above 100 mg/L (aOR 7.48, 2.34–23.93, reference ≤ 20 mg/L); the location of the GP practice in an urban setting (aOR 2.27, 1.18–4.37); and the GP’s number of years of experience (aOR per year 1.05, 1.01–1.09). …”
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The Association Between Intradialytic Symptom Clusters and Recovery Time in Patients Undergoing Maintenance Hemodialysis: An Exploratory Analysis by Arrti A. Bhasin, Jennifer M. MacRae, Braden Manns, Kelvin C. W. Leung, Amber O. Molnar, Jason W. Busse, David Collister, K Scott Brimble, Christian G. Rabbat, Jessica Tyrwhitt, Andrea Mazzetti, Michael Walsh

“…The second cluster included nausea/vomiting, diarrhea and chest pain, and headache. The first cluster (median score: −0.56, 25th to 75th percentile: −1.18 to 0.55) was independently associated with longer recovery time (odds ratio [OR] 1.62 per unit difference in score, 95% confidence interval [CI]: 1.23-2.12) and decreased PCS (−0.72 per unit difference in score, 95% CI: −1.29 to −0.15) and MCS scores (−0.82 per unit difference in score, 95% CI: −1.48 to −0.16), whereas the second cluster was not (OR 1.24, 95% CI: 0.97-1.58; PCS 0.19, 95% CI −0.46 to 0.83; MCS −0.72, 95% CI: −1.50 to 0.06). …”
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‘Grey nomad’ travellers’ use of remote health services in Australia: a qualitative enquiry of hospital managers’ perspectives by Margaret Yates, Lin Perry, Jenny Onyx, Tracy Levett-Jones

“…Traveller presentations were described as predominantly exacerbations of chronic illness such as chest pain, medication-related attendances, and accidents and injuries. …”
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Efeitos cardiovasculares da anestesia local com vasoconstritor durante exodontia em coronariopatas Cardiovascular effects of local anesthesia with vasoconstrictor during dental ext... by Valeria C. L. S. Conrado, Januário de Andrade, Gabriella A. M. C. de Angelis, Ana Carolina P. de Andrade, Lilia Timerman, Mercedes M. Andrade, Dalmo R. Moreira, Amanda G. M. R. Sousa, J. Eduardo M. R. Sousa, Leopoldo S. Piegas

“…RESULTS: Three patients in group I presented ST-segment depression (1.0 mm) during administration of anesthesia; two other patients in group I had CK-MB mass elevation, and ischemia was not observed in any other case, as assessed by the other methods. No chest pain, arrhythmias, occurrence or worsening of left ventricular segmental hypocontractility or mitral regurgitation were observed in the study. …”
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Case Report: A case of recurrent thrombosis in pediatric antiphospholipid syndrome associated with pediatric onset systemic lupus by Lingjuan Liu, Lingjuan Liu, Liqun Liu, Liqun Liu, Lu Zhang, Lu Zhang, Peng Huang, Peng Huang, Xiqiang Dang, Xiqiang Dang, Lanjun Shuai, Lanjun Shuai, Xingfang Li, Xingfang Li, Yongzhen Li, Yongzhen Li, Dingan Mao, Dingan Mao, Xiaochuan Wu, Xiaochuan Wu, Yan Cao, Yan Cao

“…She suddenly developed severe chest pain and dyspnea 3 days after hospitalization. …”
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<i>Plectranthus</i> Species with Anti-Inflammatory and Analgesic Potential: A Systematic Review on Ethnobotanical and Pharmacological Findings by Maysa de Oliveira Barbosa, Polrat Wilairatana, Giovana Mendes de Lacerda Leite, Gyllyandeson de Araújo Delmondes, Lucas Yure Santos da Silva, Silvio Caetano Alves Júnior, Lindaiane Bezerra Rodrigues Dantas, Daniel Souza Bezerra, Izabel Cristina Santiago Lemos de Beltrão, Diógenes de Queiroz Dias, Jaime Ribeiro-Filho, Cícero Francisco Bezerra Felipe, Henrique Douglas Melo Coutinho, Irwin Rose Alencar de Menezes, Marta Regina Kerntopf Mendonça

“…The indications for pain conditions included headache, sore throat, heartburn, menstrual cramp, colic, toothache, stomachache, migraine, chest pain, abdominal pain, local pain, labor pain, and recurring pain. …”
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Factors Responsible for Prehospital Delay in Patients with Acute Coronary Syndrome in Bangladesh by Md. Fakhrul Islam Khaled, Dipal Krishna Adhikary, Md. Mazharul Islam, Md. Mashiul Alam, Mohammad Walidur Rahman, MSI Tipu Chowdhury, Roseyat Perveen, Sharmin Ahmed, Eshita Ashab, Shiblee Sadeque Shakil, Sanjida Ansari, Bikash Chandra Das, Noor Mohammad, Mohammad Abul Ehsan, Abu Baqar Md. Jamil, Zahidul Mostafa, Zainal Abedin, Sajal Krishna Banerjee

“…The patients with previous myocardial infarction (MI) and chest pain arrived significantly earlier at the hospital following ACS onset. …”
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Pregnancy-Associated Spontaneous Coronary Acute Dissection as a Cause of Sudden Cardiac Death—Autopsy Findings and Literature Review: Is COVID-19 Related? by Timur Hogea, Bogdan Andrei Suciu, Laura Chinezu, Klara Brinzaniuc, Emil Marian Arbănași, Ancuța Ungureanu, Réka Kaller, Cosmin Carașca, Eliza Mihaela Arbănași, Vlad Vunvulea, Ioana Hălmaciu, Adrian Vasile Mureșan, Eliza Russu, Claudiu Constantin Ciucanu, Casandra Maria Radu, Carmen Corina Radu

“…This present study reports two cases over 35 years, one being infected with SARS-COV2 one month before the event and the other being tested positive during admission, both asymptomatic, who were declared healthy on periodic clinical evaluations, with pregnancies over 35 weeks, with normal fetal development, which suddenly caused chest pain, dyspnea, and loss of consciousness, required emergency c-sections, and died suddenly after they were performed. …”
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The utility of cardiopulmonary exercise testing in athletes and physically active individuals with or without persistent symptoms after COVID-19 by Gisele Mendes Brito, Danilo Marcelo Leite do Prado, Diego Augusto Rezende, Luciana Diniz Nagem Janot de Matos, Irineu Loturco, Irineu Loturco, Marcelo Luiz Campos Vieira, Ana Lúcia de Sá Pinto, Rodrigo Otávio Bougleux Alô, Lorena Christine Araújo de Albuquerque, Flavia Riva Bianchini, Ana Jéssica Pinto, Hamilton Roschel, Ítalo Ribeiro Lemes, Bruno Gualano, Coalition SPORT-COVID-19

“…Persistent symptoms were defined as fatigue, dyspnea, chest pain, dizziness, tachycardia, and exertional intolerance persisting &gt;2 months after COVID-19 diagnosis.ResultsA total of 46 participants were included; sixteen (34.8%) were asymptomatic and thirty participants (65.2%) reported persistent symptoms, with fatigue and dyspnea being the most reported ones (43.5 and 28.1%). …”
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Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19 by Jitendra Kumar Chaudhary, Deepika Saini, Pankaj Kumar Chaudhary, Anurag Maurya, Ganesh Kumar Verma, Akhilesh Kumar Gupta, Rakesh Roshan, Tarun Kumar Vats, Nidhi Garg, Deepika Yadav, Nimita Kant, Anil Kumar Meena, Anissa Atif Mirza-Shariff

“…After an average incubation period of 2–14 days, the majority of infected individuals remain asymptomatic and/or mildly symptomatic, whereas the remaining individuals manifest a myriad of clinical symptoms, including fever, sore throat, dry cough, fatigue, chest pain, and breathlessness. SARS-CoV-2 exploits the angiotensin converting enzyme 2 (ACE-2) receptor for cellular invasion, and lungs are amongst the most adversely affected organs in the body. …”
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