Brief Research Report: Quantitative Analysis of Potential Coronary Microvascular Disease in Suspected Long-COVID Syndrome by Patrick Doeblin, Patrick Doeblin, Fridolin Steinbeis, Cian M. Scannell, Collin Goetze, Sarah Al-Tabatabaee, Jennifer Erley, Alessandro Faragli, Felix Pröpper, Martin Witzenrath, Thomas Zoller, Thomas Zoller, Christian Stehning, Holger Gerhardt, Holger Gerhardt, Javier Sánchez-González, Ebraham Alskaf, Titus Kühne, Titus Kühne, Burkert Pieske, Burkert Pieske, Burkert Pieske, Carsten Tschöpe, Carsten Tschöpe, Carsten Tschöpe, Amedeo Chiribiri, Sebastian Kelle, Sebastian Kelle, Sebastian Kelle

“…We examined whether microvascular perfusion, measured by quantitative stress perfusion cardiac magnetic resonance (CMR), is impaired in patients with persistent cardiac symptoms post-COVID-19.MethodsOur population consisted of 33 patients post-COVID-19 examined in Berlin and London, 11 (33%) of which complained of persistent chest pain and 13 (39%) of dyspnea. The scan protocol included standard cardiac imaging and dual-sequence quantitative stress perfusion. …”
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Residual Cough and Asthma-like Symptoms Post-COVID-19 in Children by Abdullah Al-Shamrani, Khalid Al-Shamrani, Maram Al-Otaibi, Ayed Alenazi, Hareth Aldosaimani, Zeyad Aldhalaan, Haleimah Alalkami, Abdullah A. Yousef, Sumayyah Kobeisy, Saleh Alharbi

“…For those reporting residual cough, 39.3% found that it affected school attendance and daily activities, 31.1% reported associated chest pain, 51.9% associated it with wheezing, and 27.1% associated it with shortness of breath. …”
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Serum Organ-Specific Anti-Heart and Anti-Intercalated Disk Autoantibodies as New Autoimmune Markers of Cardiac Involvement in Systemic Sclerosis: Frequency, Clinical and Prognostic... by Alida Linda Patrizia Caforio, Giacomo De Luca, Anna Baritussio, Mara Seguso, Nicoletta Gallo, Elisa Bison, Maria Grazia Cattini, Elena Pontara, Luna Gargani, Alessia Pepe, Corrado Campochiaro, Mario Plebani, Sabino Iliceto, Giovanni Peretto, Antonio Esposito, Lorenzo Tofani, Alberto Moggi-Pignone, Lorenzo Dagna, Renzo Marcolongo, Marco Matucci-Cerinic, Cosimo Bruni

“…AHAs were associated with interstitial lung disease (<i>p</i> = 0.04), history of chest pain (<i>p</i> = 0.026), abnormal troponin (<i>p</i> = 0.006), AIDA (<i>p</i> = 0.000), and current immunosuppression (<i>p</i> = 0.01). …”
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Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) community-randomised t... by Eveline Klinkenberg, Sian Floyd, Kwame Shanaube, Linda Mureithi, Thomas Gachie, Petra de Haas, Barry Kosloff, Peter J Dodd, Maria Ruperez, Chali Wapamesa, James Michael Burnett, Nico Kalisvaart, Nkatya Kasese, Redwaan Vermaak, Albertus Schaap, Sarah Fidler, Richard Hayes, Helen Ayles, TREATS study team

“…Sputum eligibility was determined by the presence of a cough for ≥2 weeks, or ≥2 of 5 "TB suggestive" symptoms (cough, weight loss for ≥4 weeks, night sweats, chest pain, and fever for ≥2 weeks), or chest X-ray CAD4TBv5 score ≥50, or no available X-ray results. …”
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Sustained seropositivity up to 20.5 months after COVID-19 by Carlota Dobaño, Anna Ramírez-Morros, Selena Alonso, Rocío Rubio, Gemma Ruiz-Olalla, Josep Vidal-Alaball, Dídac Macià, Queralt Miró Catalina, Marta Vidal, Aina Fuster Casanovas, Esther Prados de la Torre, Diana Barrios, Alfons Jiménez, Jasmina Zanoncello, Natalia Rodrigo Melero, Carlo Carolis, Luis Izquierdo, Ruth Aguilar, Gemma Moncunill, Anna Ruiz-Comellas

“…Antibody levels at the time point closest to infection were associated with age, smoking, obesity, hospitalization, fever, anosmia/hypogeusia, chest pain, and hypertension in multivariable regression models. …”
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MYELODYSPLASIA/MYELOPROLIFERATIVE WITH RING SIDEROBLAST AND THROMBOCYTOSIS OR UNCLASSIFIABLE (MDS/MPNI) by MM Garcia, SLBG Oliveira, ACP Silva, CM Freitas, JPB Júnior, JOR Cassiano, RDA Conserva, ERM Neri, VM Sthel, VLP Figueiredo

“…There are reports of vasomotor symptoms such as headache, palpitations, paresthesia, atypical chest pain and erythromelalgia. Some patients have acquired von Willebrand disease, particularly in the presence of extreme thrombocytosis (>1000×109/L) and risk of bleeding with antiplatelet therapy. …”
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Cardiometabolic predictors of high-risk CCTA phenotype in a diverse patient population by Toshiki Kuno, Javier Arce, Michael Fattouh, Sharmila Sarkar, John P Skendelas, Jonathan Daich, Aldo L Schenone, Lili Zhang, Carlos J Rodriguez, Salim S Virani, Piotr J Slomka, Leslee J Shaw, Eric E Williamson, Daniel S Berman, Mario J Garcia, Damini Dey, Leandro Slipczuk

“…Methods: The patient population consisted of consecutive patients who underwent CCTA for stable chest pain and had a complete cardiometabolic panel including lipoprotein(a). …”
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Acute myocardial infarction hospital admissions and deaths in England: a national follow-back and follow-forward record-linkage study by Perviz Asaria, MRCP, Paul Elliott, ProfMBBS, Margaret Douglass, MEng, Ziad Obermeyer, MD, Michael Soljak, PhD, Azeem Majeed, ProfMD, Majid Ezzati, ProfFMedSci

“…The most common causes of admission in people who did not have an acute myocardial infarction diagnosis but went on to die of acute myocardial infarction as the underlying cause of death were other circulatory conditions (7566 [35%] of 21 677 deaths), symptomatic diagnoses including non-specific chest pain, dyspnoea and syncope (1368 [6%] deaths), and respiratory disorders (2662 [12%] deaths), mainly pneumonia and chronic obstructive airways disease. …”
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Nicotine replacement therapy versus control for smoking cessation by Hartmann-Boyce, J, Chepkin, S, Ye, W, Bullen, C, Lancaster, T

“…However, chest pains and palpitations were rare in both groups and serious adverse events were extremely rare.…”

Antidepressants versus placebo for panic disorder in adults by Bighelli, I, Castellazzi, M, Cipriani, A, Girlanda, F, Guaiana, G, Koesters, M, Turrini, G, Furukawa, TA, Barbui, C

“…<strong>Background</strong> Panic disorder is characterised by repeated, unexpected panic attacks, which represent a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes, and in which at least four of 13 characteristic symptoms are experienced, including racing heart, chest pain, sweating, shaking, dizziness, flushing, stomach churning, faintness and breathlessness. …”

NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post‐Myocardial Infarction via Human Antigen R by Chenghu Guo, Wei Ji, Wei Yang, Qiming Deng, Tengfei Zheng, Zunzhe Wang, Wenhai Sui, Chungang Zhai, Fangpu Yu, Bo Xi, Xiao Yu, Feng Xu, Qunye Zhang, Wencheng Zhang, Jing Kong, Meng Zhang, Cheng Zhang

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Factors Associated With Mortality Among the COVID-19 Patients Treated at Gulu Regional Referral Hospital: A Retrospective Study by Steven Baguma, Steven Baguma, Christopher Okot, Christopher Okot, Nelson Onira Alema, Nelson Onira Alema, Paska Apiyo, Paska Apiyo, Paska Layet, Paska Layet, Denis Acullu, Denis Acullu, Johnson Nyeko Oloya, Denis Ochula, Denis Ochula, Pamela Atim, Pamela Atim, Patrick Odong Olwedo, Patrick Odong Olwedo, Smart Godfrey Okot, Smart Godfrey Okot, Freddy Wathum Drinkwater Oyat, Janet Oola, Janet Oola, Eric Nzirakaindi Ikoona, Judith Aloyo, Judith Aloyo, David Lagoro Kitara, David Lagoro Kitara

“…Mortality was highest in diabetics 11 (34.4%), cardiovascular diseases 12 (37.5%), hypertensives 10 (31.3%), females 18 (56.3%), ≥50-year-olds 19 (59.4%), no formal education 14 (43.8%), peasant farmers 12 (37.5%) and those who presented with difficulty in breathing/shortness of breath and chest pain 32 (100.0%), oxygen saturation (SpO2) at admission &lt;80 4 (12.5%), general body aches and pains 31 (96.9%), tiredness 30 (93.8%) and loss of speech and movements 11 (34.4%). …”
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High-sensitivity troponin I with or without ultra-sensitive copeptin for the instant rule-out of acute myocardial infarction by Fabrizio Ricci, Fabrizio Ricci, Fabrizio Ricci, Johannes T. Neumann, Johannes T. Neumann, Nicole Rübsamen, Nils A. Sörensen, Nils A. Sörensen, Francisco Ojeda, Ivana Cataldo, Tanja Zeller, Tanja Zeller, Sarina Schäfer, Tau S. Hartikainen, Maria Golato, Stefano Palermi, Marco Zimarino, Stefan Blankenberg, Stefan Blankenberg, Dirk Westermann, Dirk Westermann, Raffaele De Caterina, Raffaele De Caterina

“…We aimed at testing and comparing diagnostic performance and prognostic value of two different single-sampling biomarker strategies for the instant rule-out of AMI.MethodsFrom the Biomarkers in Acute Cardiac Care (BACC) cohort, we recruited consecutive patients with acute chest pain and suspected AMI presenting to the Emergency Department of the University Medical Center Hamburg-Eppendorf, Hamburg, Germany. …”
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Diagnostic dilemma: Saccular aneurysm or pseudoaneurysm of the ascending aorta with dissection above level of leaflets by Maryam Mehrpooya, Mehrdad Salehi, Ramin Eskandari, Zeinab Shajirat, Allahyar Golabchi, Majid Mazoochi

“…</span></p><span style="font-family: Times New Roman; font-size: small;"> </span><p class="abstract" style="margin: 3pt 1cm 0pt;"><strong><span style="mso-bidi-font-size: 13.0pt;"><span style="mso-tab-count: 1;"><span style="font-family: Georgia; font-size: x-small;"> </span></span></span></strong><strong><span style="font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; font-size: 9pt; mso-bidi-font-size: 12.0pt; mso-bidi-language: AR-SA;">CASE REPORT: </span></strong><span style="font-size: x-small;"><span style="font-family: Georgia;"><span style="mso-ansi-language: EN-GB; mso-bidi-font-style: italic;" lang="EN-GB">An 85-year-old man underwent elective coronary angiography for chest pain work-up. Our evaluation by invasive angiography and CT angiography showed aortic dissection. …”
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The updated pre-test probability model of the 2019 ESC guidelines improves prediction of obstructive coronary artery disease by Pedro M. Lopes, Francisco Albuquerque, Pedro Freitas, Bruno M.L. Rocha, Gonçalo J.L. Cunha, Ana Coutinho Santos, João Abecasis, Sara Guerreiro, Carla Saraiva, Miguel Mendes, António M. Ferreira

“…We aimed to compare the performance of the new PTP method against the 2013 prediction model in patients with stable chest pain undergoing coronary computed tomography angiography (CCTA) for suspected CAD. …”
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Heart Failure Association of the European Society of Cardiology position paper on the management of left ventricular assist device‐supported patients for the non‐left ventricular a... by Davor Milicic, Binyamin Ben Avraham, Ovidiu Chioncel, Yaron D. Barac, Eva Goncalvesova, Avishai Grupper, Johann Altenberger, Maria Frigeiro, Arsen Ristic, Nicolaas De Jonge, Steven Tsui, Jacob Lavee, Giuseppe Rosano, Marisa Generosa Crespo‐Leiro, Andrew J.S. Coats, Petar Seferovic, Frank Ruschitzka, Marco Metra, Stefan Anker, Gerasimos Filippatos, Stamatis Adamopoulos, Miriam Abuhazira, Jeremy Elliston, Israel Gotsman, Righab Hamdan, Yoav Hammer, Tal Hasin, Lorrena Hill, Osnat Itzhaki Ben Zadok, Wilfried Mullens, Sanemn Nalbantgil, Massimo Francesco Piepoli, Piotr Ponikowski, Luciano Potena, Arjang Ruhparwar, Aviv Shaul, Laurens F. Tops, Stephan Winnik, Tiny Jaarsma, Finn Gustafsson, Tuvia Ben Gal

“…In this second part of the trilogy on the management of LVAD‐supported patients for the non‐LVAD specialist healthcare provider, definitions and structured approach to the LVAD‐supported patient presenting to the emergency department with bleeding, neurological event, pump thrombosis, chest pain, syncope, and other events are presented. …”
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Sex Differences in Stress-Induced (Takotsubo) Cardiomyopathy by Waddah Maskoun, MD, FHRS, FACC, Bilal Alqam, MD, Fuad Habash, MD, Zaid Gheith, MD, Stephen G. Sawada, MD, Srikanth Vallurupalli, MD

“…Men had a higher median age (65 vs 60 years; P < 0.001), and women were more likely to present with chest pain (68.7% vs 44.1%; P < 0.001). Physical triggers were more common in men (68.7% vs 44.1%, P < 0.001). …”
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Epidemiology and Clinical Presentation of Children Hospitalized with SARS-CoV-2 Infection in Suburbs of Paris by Louise Gaborieau, Celine Delestrain, Philippe Bensaid, Audrey Vizeneux, Philippe Blanc, Aurélie Garraffo, Emilie Georget, Arnaud Chalvon, Nathalie Garrec, Yacine Laoudi, Emmanuelle Varon, Sébastien Rouget, Alexandre Pupin, Khaled Abdel Aal, David Toulorge, Sarah Ducrocq, Catherine Barrey, Letitia Pantalone, Blandine Robert, Lydie Joly-Sanchez, Caroline Thach, Caroline Masserot-Lureau, Jamilé Chahine, Veronica Risso Garcia-Roudaut, Jonathan Rozental, Sylvie Nathanson, Mohamed Khaled, Alexis Mandelcwajg, Nadia Demayer, Stéphanie Muller, Mustapha Mazerghane, Ralph Epaud, Béatrice Pellegrino, Fouad Madhi

“…Only 10 (5.2%) children had anosmia and five (2.6%) had chest pain. An underlying condition was identified in almost 30% of the children in our study. …”
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Novel applications of cardiovascular magnetic resonance in acute myocardial injury by Shanmuganathan, M

“…Characterising of the extent and nature of acute myocardial injury in these patients (presenting twelve to forty-eight hours after the onset of chest pain) prior to ICA may of be of use when deciding whether to revascularise. …”

PECULIARITIES OF THE COURSE AND TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH SYNDROME OF UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA. (SYSTEMATIC LITERATURE REVIE... by Iryna Romash

“…In  particular, these patients complained more frequently of heartburn, severe chest pain, more frequent gastroesophageal and duodenogastric refluxes and erosion of the mucous membrane of the lower third of the esophagus. …”
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