<i>N</i>-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese Mice by Nguyen Khanh Hoang, Eiji Maegawa, Shigeru Murakami, Stephen W. Schaffer, Takashi Ito

“…While <i>N</i>-chlorotaurine (also known as taurine chloramine; TauCl) has anti-inflammatory effects in cells, its effects against pulmonary and systemic inflammation after lung infection has not been elucidated. …”
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Analysis of biofilm-resistance factors in Singapore drinking water distribution system by Li, Yuanzhe, Wang, Yilin, Xiao, Peng, Narasimalu, Srikanth, Dong, Zhili

“…This article critically reviews current Singapore DWDS by analysing the leading and lagging performance of two stages, granulated active carbon (GAC) filtering and secondary disinfection by chloramine, which are highly relevant with the biofilm resistance. …”
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A New Insight into Meloxicam: Assessment of Antioxidant and Anti-Glycating Activity in In Vitro Studies by Cezary Pawlukianiec, Małgorzata Ewa Gryciuk, Kacper Maksymilian Mil, Małgorzata Żendzian-Piotrowska, Anna Zalewska, Mateusz Maciejczyk

“…Glucose, fructose, ribose, glyoxal and methylglyoxal were used as glycating agents, while chloramine T was used as an oxidant. We evaluated the antioxidant properties of albumin (2,2-di-phenyl-1-picrylhydrazyl radical scavenging capacity, total antioxidant capacity and ferric reducing antioxidant power), the intensity of protein glycation (Amadori products, advanced glycation end products) and glyco-oxidation (dityrosine, kynurenine, N-formylkynurenine, tryptophan and amyloid-β) as well as the content of protein oxidation products (advanced oxidation protein products, carbonyl groups and thiol groups). …”
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Distribution of 131I-labeled Bothrops erythromelas venom in mice by C.M.L. Vasconcelos, R.C. Valença, E.A. Araújo, J.C.A. Modesto, M.M. Pontes, T.K. Brazil, M.C. Guarnieri

“…B. erythromelas venom and albumin were labeled individually with 131I by the chloramine T method, and separated in a Sephacryl® S-200 column. …”
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Engineering a HEK-293T exosome-based delivery platform for efficient tumor-targeting chemotherapy/internal irradiation combination therapy by Congcong Wang, Ning Li, Yutian Li, Shasha Hou, Wenxin Zhang, Zhaowei Meng, Shen Wang, Qiang Jia, Jian Tan, Renfei Wang, Ruiguo Zhang

“…This platform was loaded with doxorubicin (Dox) and labeled with radioiodine-131 (131I) using the chloramine-T method. iRGD exosomes showed highly efficient targeting and Dox delivery to integrin αvβ3-positive anaplastic thyroid carcinoma (ATC) cells as demonstrated by confocal imaging and flow cytometry in vitro and an excellent tumor-targeting capacity confirmed by single-photon emission computed tomography-computed tomography after labeling with 131I in vivo. …”
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Taurine Bromamine: Reactivity of an Endogenous and Exogenous Anti-Inflammatory and Antimicrobial Amino Acid Derivative by Luiza De Carvalho Bertozo, Nelson Henrique Morgon, Aguinaldo Robinson De Souza, Valdecir Farias Ximenes

“…Tau-NHBr reactivity was compared with HOBr, hypochlorous acid (HOCl) and taurine chloramine (Tau-NHCl). The second-order rate constants (k2) for the reactions between Tau-NHBr and tryptophan (7.7 × 102 M−1s−1), melatonin (7.3 × 103 M−1s−1), serotonin (2.9 × 103 M−1s−1), dansylglycine (9.5 × 101 M−1s−1), tetramethylbenzidine (6.4 × 102 M−1s−1) and H2O2 (3.9 × M−1s−1) were obtained. …”
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Comparative evaluation of disinfectant efficacy against biofilm-residing microorganisms by Lyudmila S. Fedorova, Anastasia V. Ilyakova

“…The effect of the following disinfectants has been evaluated: alkyldimethylbenzylammonium chloride (ADBAC), tertiary amine (TA), polyhexamethylene guanidine chloride (PHMG), hydrogen peroxide (HP), chloramine (CA), dichloroisocyanuric acid sodium salt (Na DCC), sodium hypochlorite (HC), ethyl alcohol (EA), glutaraldehyde (GA)) against Pseudomonas aeruginosa ATCC 15442 and Staphylococcus aureus ATCC 6538-P BFs. …”
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Simultaneous determination of volatile phenol, cyanide, anionic surfactant, and ammonia nitrogen in drinking water by a continuous flow analyzer by Guofu Qin, Keting Zou, Fengrui He, Ji Shao, Bei Zuo, Jia Liu, Ruixiao Liu, Bixia Yang, Guipeng Zhao

“…Cyanide in the distillate subsequently reacted with chloramine T to form cyanogen chloride, which then formed a blue complex with pyridinecarboxylic acid that was measured colorimetrically at 630 nm. …”
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Effectiveness of detergents and disinfectants in the production of cow’s milk by Vasyl Liasota, Nadiia Bohatko, Svitlana Tkachuk, Nataliia Bukalova, Oksana Khitska

“…Detergents and disinfectants “Chloramine B”, “Sanalcalin” and “Neochlor” have a detrimental effect on the growth of test cultures of E. coli, S. aureus and P. aeruginosa. …”
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Discovery of New Coumarin-Based Lead with Potential Anticancer, CDK4 Inhibition and Selective Radiotheranostic Effect: Synthesis, 2D & 3D <i>QSAR</i>, Molecular Dynamics, In Vitro... by Mona O. Sarhan, Somaia S. Abd El-Karim, Manal M. Anwar, Raghda H. Gouda, Wafaa A. Zaghary, Mohammed A. Khedr

“…The selectivity of the newly discovered lead compound <b>2b</b> toward localization in tumor cells was confirmed by a radioiodination biological assay that was done via electrophilic substitution reaction utilizing the oxidative effect of chloramine-t. <b>¹³¹I-2b</b> showed good in vitro stability up to 4 h. …”
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Assessment of bioactive peptides derived from laminin-111 as prospective breast cancer-targeting agents by Fernanda Ferreira Mendonça, Danielle Vieira Sobral, Ana Claudia Ranucci Durante, Ana Cláudia Camargo Miranda, Jorge Mejia, Daniele de Paula Faria, Fabio Luiz Navarro Marques, Marycel Figols de Barboza, Leonardo Lima Fuscaldi, Luciana Malavolta

“…Iodine-131 (131I) radiolabeling was performed using the chloramine T method, exhibiting high radiochemical yield and stability for [131I]I-YIKVAV and [131I]I-YIGSR. …”
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Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvi... by Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, Zhang M, Guo D, Yang X

“…The levels of inflammatory cytokines, uremic toxins, and NF-κB signaling pathway were detected by RT-PCR, ELISA, chloramine-T method or Western blotting. Redundancy analysis biplot and Spearman’s rank correlation coefficient were used for correlation analysis.Results: HGF significantly improved renal function and pathological injuries of CKD. …”
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Radiosynthesis and in-vitro identification of a molecular probe 131I-FAPI targeting cancer-associated fibroblasts by Yaxin Tian, Yaxin Tian, Yanghongyan Jiang, Ping Ma, Xiaowei Ma, Liang Du, Fengkui Wang, Xiaodong Yu, Qian Zhao

“…The aim of this study was to radiosynthesize a novel molecular probe 131I-FAPI and evaluate its in-vitro targeting and biological characteristics.MethodsThe structurally modified FAPI was labelled with 131I through the chloramine-T method. The radiolabeling rate was then detected by thin-layer chromatography (TLC). …”
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Preliminary evaluation of the antiglycoxidant activity of verapamil using various in vitro and in silico biochemical/biophysical methods by Miłosz Nesterowicz, Kamil Klaudiusz Lauko, Karolina Dańkowska, Daria Trocka, Małgorzata Żendzian-Piotrowska, Jerzy Robert Ładny, Anna Zalewska, Mateusz Maciejczyk

“…As glycating factors, sugars (glucose, fructose, and ribose) and aldehyde (glyoxal) were used. Chloramine T was used as an oxidizing agent. Aminoguanidine (protein glycation inhibitor) and Trolox (antioxidant) were used as control substances. …”
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Experimental study of iodine-131 labeling of a novel tumor-targeting peptide, TFMP-Y4, in the treatment of hepatocellular carcinoma with internal irradiation by Juan Du, Weiwei Ren, Wenjie Liu, Yixuan Zhou, Yushan Li, Qingyi Lai, Xiongying Liu, Tongsheng Chen, Wenjuan Liu, Zhuanming Chen, Jinhe Zhang, Peipei Zhang, Jianwei Yuan

“…Methods (1) 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) analysis revealed the inhibitory effects of Caerin 1.1 and TFMP-Y4 on Hepg2 and LO2 cell growth. (2) The chloramine-T method was used to prepare 131I-Caerin 1.1 and 131I-TFMP-Y4. (3) Uptake and elution assays revealed that Hepg2 cells bound and retained 131I-Caerin 1.1 and 131I-TFMP-Y4, and the inhibitory effects on Hepg2 cells were verified with cellular proliferation/toxicity assays. (4) A hormonal nude mouse model was established to study the in vivo therapeutic effects of the peptides alone, 131I-Caerin 1.1 and 131I-TFMP-Y4. …”
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Comparative Evaluation of Radiochemical and Biological Properties of ¹³¹I- and [^99mTc]Tc(CO)₃-Labeled RGD Analogues Planned to Interact with the α<... by Danielle V. Sobral, Leonardo L. Fuscaldi, Ana Claudia R. Durante, Fernanda F. Mendonça, Larissa R. de Oliveira, Ana Cláudia C. Miranda, Jorge Mejia, Wagner R. Montor, Marycel F. de Barboza, Luciana Malavolta

“…Both peptides were chemically synthesized, purified and radiolabeled with ¹³¹I and [^99mTc][Tc(CO)₃]⁺ using the chloramine-T and tricarbonyl methodologies, respectively. …”
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Swimming pool water disinfection by-products profiles and association patterns by Eunate Abilleira, Fernando Goñi-Irigoyen, Juan J. Aurrekoetxea, María A. Cortés, Mikel Ayerdi, Jesús Ibarluzea

“…The aim of this work was to determine and study the concentration of different groups of disinfection by-products (DBPs): trihalomethanes, haloacetic acids, haloacetonitriles, haloacetones and combined chlorine (as an indicator of chloramine levels), in the water of 175 public swimming pools in Gipuzkoa (Basque Country, Spain). …”
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131I-Caerin 1.1 and 131I-Caerin 1.9 for the treatment of non-small-cell lung cancer by Na Liu, Tiantian He, Zewei Xiao, Juan Du, Keke Zhu, Xiongying Liu, Tongsheng Chen, Wenjuan Liu, Guoying Ni, Xiaosong Liu, Xiaosong Liu, Tianfang Wang, Tianfang Wang, Jiangtao Quan, Jinhe Zhang, Peipei Zhang, Jianwei Yuan

“…ObjectiveTo investigate the effect of the 131I-labeled high-affinity peptides Caerin 1.1 and Caerin 1.9 for the treatment of A549 human NSCLC cells.Methods① 3-[4,5-Dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) and plate clone formation assays were performed to confirm the in vitro anti-tumor activity of Caerin 1.1 and Caerin 1.9. ② Chloramine-T was used to label Caerin 1.1 and Caerin 1.9 with 131I, and the Cell Counting Kit 8 assay was performed to analyze the inhibitory effect of unlabeled Caerin 1.1, unlabeled Caerin 1.9, 131I-labeled Caerin 1.1, and 131I-labeled Caerin 1.9 on the proliferation of NSCLC cells. …”
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ASSESSMENT OF IN VITRO STUDIES OF [131I]I-LABELED DEDEYFELV PEPTIDE AS PROSPECTIVE BIOMARKER FOR GLIOBLASTOMA by Fernanda Paiva Augusto Rodrigues, Júlia Calviello Giordano, Danielle Vieira Sobral, Ana Cláudia Camargo Miranda, Leonardo Lima Fuscaldi, Marycel Figols de Barboza, João Luiz Vitorino Araújo, Luciana Malavolta

“…The DEDEYFELV (20 nmol) was radiolabeled with the [131I]NaI radionuclide (18.5 MBq), using the chloramine-T method. The radiochemical yield of the [131I]I-DEDEYFELV was carried out by on Whatmann 3MM strips using 95% MeOH / 5% H2O as eluent. …”
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Is flushing necessary during building closures? A study of water quality and bacterial communities during extended reductions in building occupancy by Hannah Greenwald, Hannah Greenwald, Lauren C. Kennedy, Lauren C. Kennedy, Lauren C. Kennedy, Aliya Ehde, Aliya Ehde, Aliya Ehde, Yanghua Duan, Yanghua Duan, Christopher I. Olivares, Christopher I. Olivares, Rose Kantor, Rose Kantor, Kara L. Nelson, Kara L. Nelson

“…Reduced occupancy led to diminished chloramine and elevated intact cell counts, but values remained stable after additional weeks of limited water use. …”
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