Risk Factors for Postoperative Cerebrospinal Fluid Leak after Graded Multilayer Cranial Base Repair with Suturing via the Endoscopic Endonasal Approach by Takuma HARA, Hiroyoshi AKUTSU, Shuho TANAKA, Hiroyoshi KINO, Hidetaka MIYAMOTO, Rieko II, Shingo TAKANO, Eiichi ISHIKAWA

“…Maximum tumor diameter, estimated tumor volume, and chordoma tumor pathology are related to a higher risk of postoperative CSF leak.…”
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Bone sarcoma follow-up; a nationwide analysis of oncological events after initial treatment by Louren M. Goedhart, Vincent K.Y. Ho, Joris J.W. Ploegmakers, Ingrid C.M. van der Geest, Michiel A.J. van de Sande, Jos A. Bramer, Martin Stevens, Paul C. Jutte

“…Local recurrence and distant metastasis was analysed along with overall survival for high-grade chondrosarcoma, high-grade osteosarcoma, Ewing sarcoma and chordoma. Results: Median follow-up was 8,3 years for high-grade chondrosarcoma, 4,9 for high-grade osteosarcoma, 3,8 for Ewing sarcoma and 7,5 for chordoma. …”
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Reducing CSF complications by a recycled Hadad’s flap combined with autologous mucosa in secondary endoscope transsphenoidal surgery by Runfeng Wang, Gaoyang Zhou, Jin Wang, Bo Ma, Ping Wang, Guodong Gao, Shukai Sun, Zhiguo Zhang

“…Diabetes mellitus, craniopharyngioma, chordoma and the utilization of artificial dura were independent risk factors for CSF complications in secondary transsphenoidal surgery through univariate and multivariate logistic regression. …”
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Partial sacrectomy by single posterior approach. by Pedro Luis Bazán, Sergio Terraza, Álvaro Enrique Borri, Martin Medina

“…Of the primary, the chordoma is the most frequent malignant and giant cell tumor of the benign. …”
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Prognostic significance and therapeutic potentials of immune checkpoints in osteosarcoma by Vafa Meftahpour, Ali Aghebati-Maleki, Ali Fotouhi, Elham Safarzadeh, Leili Aghebati-Maleki

“…Bone sarcomas have several subtypes, with the most common ones being chordoma, chondrosarcoma, Ewing sarcoma, and osteosarcoma. …”
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[Sellar tumors] by Weber, M, Zoubaa, S, Politi, M, Grunwald, I, Essig, M

“…Differential diagnoses comprise besides adenoma among others craniopharyngioma, meningioma, glioma, germinoma, hamartoma, aneurysm, trigeminal schwannoma, pituitary carcinoma, chordoma, metastasis, infection, and empty sella. Characteristic imaging findings are presented and correlated to micro- and macro-pathology.…”

Sellar tumors by Weber, M, Zoubaa, S, Politi, M, Grunwald, I, Essig, M

“…Differential diagnoses comprise besides adenoma among others craniopharyngioma, meningioma, glioma, germinoma, hamartoma, aneurysm, trigeminal schwannoma, pituitary carcinoma, chordoma, metastasis, infection, and empty sella. Characteristic imaging findings are presented and correlated to micro- and macropathology. © 2007 Springer Medizin Verlag.…”

[Skull base tumors] by Ahlhelm, F, Nabhan, A, Naumann, N, Grunwald, I, Shariat, K, Reith, W

“…The most common neoplasms of the posterior skull base, including the CP angle, are neurinoma, meningioma, nasopharyngeal carcinoma, chordoma and paraganglioma. One major task of imaging is the evaluation of the exact tumor extent as well as its relationship to the neighboring neurovascular structures. …”

Skull base tumors by Ahlhelm, F, Nabhan, A, Naumann, N, Grunwald, I, Shariat, K, Reith, W

“…The most common neoplasms of the posterior skull base, including the CP angle, are neurinoma, meningioma, nasopharyngeal carcinoma, chordoma and paraganglioma. One major task of imaging is the evaluation of the exact tumor extent as well as its relationship to the neighboring neurovascular structures. …”

Endoscopic transsphenoidal resection of a non-functioning ectopic pituitary adenoma located in the clivus: a case report and literature review by Jiangang Liu, Chengyuan Ji

“…Abstract We successfully removed a rare ectopic pituitary adenoma from a 64-year-old female patient initially misdiagnosed with a chordoma. The tumor was located in the slope region and posed a challenge due to its rarity and location. …”
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Evaluation of epidermal growth factor receptor in odontogenic tumors and rare soft tissue tumors by immunohistochemical and fluorescence in situ hybridization methods by Aysun Uğuz, Gülfiliz Gönlüşen, Kıvılcım Erdoğan, Mehmet Deveci, Melek Ergin, Özge Dinigüzel, Serdar Özbarlas

“…Conclusion: Our findings highlight that EGFR plays an important role in chordoma pathogenesis in soft tissue tumors. In addition to odontogenic tumors; two cases of vascular neoplasia, composite and retiform hemangioendothelioma, exhibited EGFR gene amplification. …”
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Rare Primary Malignant Bone Sarcomas by Emanuela Palmerini, Alberto Righi, Eric L. Staals

“…Rare primary malignant bone sarcomas (RPMBS), other than osteosarcoma, chondrosarcoma, chordoma, and Ewing sarcoma, account for about 5–10% of primary bone tumors and represent a major diagnostic challenge. …”
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Congenital Nasal Chondromesenchymal Hamartoma by Ruth S. Estimar, Mario Adrian M. Zafra, Ramon Antonio B. Lopa

“…Histopathology and immunohistochemistry of an intranasal biopsy were interpreted as chordoma, a malignant tumor. Following surgical excision, the final histopathologic diagnosis was chondroid hamartoma. …”
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Immunotherapy for SMARCB1-Deficient Sarcomas: Current Evidence and Future Developments by Carine Ngo, Sophie Postel-Vinay

“…Among these, the core subunit SMARCB1 is the most frequently mutated, and SMARCB1 loss represents a founder driver event in several malignancies, such as malignant rhabdoid tumors (MRT), epithelioid sarcoma, poorly differentiated chordoma, and renal medullary carcinoma (RMC). Intriguingly, SMARCB1-deficient pediatric MRT and RMC have recently been reported to be immunogenic, despite their very simple genome and low tumor mutational burden. …”
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The presence and absence of lymphatic vessels in the adult human intervertebral disc: relation to disc pathology. by Kliskey, K, Williams, K, Yu, J, Jackson, D, Urban, J, Athanasou, N

“…Our findings also indicate that chordoma, a tumour of notochordal origin, spreads to regional lymph nodes via lymphatics in para-spinal soft tissues.…”

Crowned dens syndrome by Norma Belfiore, Vito Privitera, Giampaolo Carmosino, Giulio Doveri

“…Differential diagnosis of fever of unknown origin (FUO) should include crowned dens syndrome specially in the elderly after exclusion of several endocrine or metabolic disorders, infection diseases (meningitis), arthritis (psoriatic arthritis and ankylosing spondylitis) and tumours (chordoma, meningioma, osteoblastoma).</p>…”
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Smooth muscle actin expression in primary bone tumours. by Hemingway, F, Kashima, T, Mahendra, G, Dhongre, A, Hogendoorn, P, Mertens, F, Athanasou, N

“…Little or no SMA was noted in Langerhans cell histiocytosis, simple bone cyst, Ewing's sarcoma, osteoblastoma, osteoid osteoma, enchondroma, osteochondroma, chondrosarcoma, myeloma, lymphoma, chordoma and adamantinoma. Our findings show that there is differential SMA expression in primary bone tumours and that identifying the presence or absence of SMA is useful in the differential diagnosis of these lesions. …”

Smooth muscle actin expression in primary bone tumours. by Hemingway, F, Kashima, T, Mahendra, G, Dhongre, A, Hogendoorn, P, Mertens, F, Athanasou, N

“…Little or no SMA was noted in Langerhans cell histiocytosis, simple bone cyst, Ewing's sarcoma, osteoblastoma, osteoid osteoma, enchondroma, osteochondroma, chondrosarcoma, myeloma, lymphoma, chordoma and adamantinoma. Our findings show that there is differential SMA expression in primary bone tumours and that identifying the presence or absence of SMA is useful in the differential diagnosis of these lesions. …”

miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions by Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Majid Samsami

“…However, this miRNA has been shown to act as a tumor suppressor in chordoma, lung cancer and ovarian cancer. In addition, several lines of evidence have shown involvement of this miRNA in the pathoetiology of bipolar disorder, myocardial infarction, obesity, renal fibrosis, rheumatoid arthritis and scar formation. …”
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Retroclival ecchordosis physaliphora: MR imaging and review of the literature. by Mehnert, F, Beschorner, R, Küker, W, Hahn, U, Nägele, T

“…Contrary to the reported findings in chordomas, none of the lesions showed contrast enhancement. …”