Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients – A validation study in plasma and cerebrospinal fluid from two Sw... by Annie Bynke, Per Julin, Carl-Gerhard Gottfries, Harald Heidecke, Carmen Scheibenbogen, Jonas Bergquist

“…Myalgic encephalomyelitis (ME) also known as ME/CFS (Chronic Fatigue Syndrome) or ME/SEID (Systemic Exertion Intolerance Disorder), is a disabling and often long-lasting disease that can drastically impair quality of life and physical/social functioning of the patients. …”
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Sintomas somáticos inexplicados clinicamente: um campo impreciso entre a psiquiatria e a clínica médica Unexplained somatic symptoms: an undefined field betwen psychiatry and inter... by José Atílio Bombana

“…FSS are characterized by symptoms, suffering and incapability rather than by specific diseases, and include but are not limited to fibromyalgia, irritable bowel syndrome, chronic fatigue syndrome, and several pain syndromes. Overlapping of clinical features raises the question of whether one or several diagnoses are present, both among different FSS and between FSS and SD, also pointing to the comorbidity issue. …”
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First insights into multidisciplinary and multispecialty long COVID networks—a SWOT analysis from the perspective of ambulatory health care professionals by Sandra Stengel, Lea Gölz, Joachim Kolb, Karin Tarbet, Stefanie Völler, Jan Koetsenruijter, Joachim Szecsenyi, Uta Merle

“…Potentials mentioned were, e.g., transferability to other diseases such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, promotion of addressing a “difficult topic” and promotion of intersectoral care concepts; risks mentioned were, e.g., limited network resources and negative effects on the development of other structures.ConclusionResulting implications for practice and research address a call to policy makers and funders to support further research to find out what generalizable results regarding usefulness, effectiveness, and efficiency including transferability to other post-infectious diseases can be derived.…”
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Cohort description: The Danish study of Functional Disorders by Dantoft TM, Ebstrup JF, Linneberg A, Skovbjerg S, Madsen AL, Mehlsen J, Brinth L, Eplov LF, Carstensen TW, Schroder A, Fink PK, Mortensen EL, Hansen T, Pedersen O, Jørgensen T

“…The survey comprises screening questionnaires for five types of FSS, ie, fibromyalgia, whiplash-associated disorder, multiple chemical sensitivity, irritable bowel syndrome, and chronic fatigue syndrome, and for the unifying diagnostic category of bodily distress syndrome. …”
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Cognitive impairment in post-acute sequelae of COVID-19 and short duration myalgic encephalomyelitis patients is mediated by orthostatic hemodynamic changes by Heather Day, Brayden Yellman, Sarah Hammer, Candace Rond, Jennifer Bell, Saeed Abbaszadeh, Greg Stoddard, Derya Unutmaz, Lucinda Bateman, Suzanne D. Vernon

“…IntroductionCognitive impairment is experienced by people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute sequelae of COVID-19 (PASC). …”
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Fadiga no trabalho: como o psicólogo pode atuar? Fatiga en el trabajo: ¿cómo el psicólogo puede actuar? Fatigue at work: how can the psychologist act? by Juliana Roman dos Santos Oliveira, Magna Gabriella Viganó, Maria Cristina Frollini Lunardelli, Luiz Carlos Canêo, Edward Goulart Júnior

“…Besides, the Chronic Fatigue Syndrome is one of many disorders that can affect the working class. …”
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Evaluation of the effects in the <i>in vitro</i> system of synthetic thymic hexapeptide on the expression levels of NF-κB, IFNα/βR and CD119 neutrophilic granulocytes in patients w... by I. V. Nesterova, E. O. Khalturina, V. N. Nelubin, S. V. Khaidukov, G. A. Chudilova

“…We observed 25 patients of both sexes aged 23 to 64 years with AChA-HVI, manifested by chronic fatigue syndrome and cognitive disorders. Study design: stage 1 clinical, ELISA, PCR methods, FC was used. …”
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Prevalence and characteristics of self-reported hypothyroidism and its association with nonorgan-specific manifestations in US sarcoidosis patients: a nationwide registry study by Bashar N. Alzghoul, Farah N. Amer, Diana Barb, Ayoub Innabi, Mamoun T. Mardini, Chen Bai, Bara Alzghoul, Tamara Al-Hakim, Noopur Singh, Mindy Buchanan, Leslie Serchuck, Diana Gomez Manjarres, Whitney W. Woodmansee, Lisa A. Maier, Divya C. Patel

“…Self-reported hypothyroidism was associated with depression (adjusted odds ratio (aOR) 1.3, 95% CI 1.01–1.6), antidepressant use (aOR 1.3, 95% CI 1.1–1.7), obesity (aOR 1.7, 95% CI 1.4–2.1), sleep apnoea (aOR 1.7, 95% CI 1.3–2.2), chronic fatigue syndrome (aOR 1.5, 95% CI 1.2–2) and was borderline associated with fibromyalgia (aOR 1.3, 95% CI 1–1.8). …”
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Persistent physical symptoms reduction intervention: a system change and evaluation in secondary care (PRINCE secondary) – a CBT-based transdiagnostic approach: study protocol for... by Trudie Chalder, Meenal Patel, Kirsty James, Matthew Hotopf, Philipp Frank, Katie Watts, Paul McCrone, Anthony David, Mark Ashworth, Mujtaba Husain, Toby Garrood, Rona Moss-Morris, Sabine Landau

“…Cognitive behavioural therapy (CBT) has demonstrated both short- and long-term efficacy with small to medium effect sizes for PPS, with larger treatment effects for specific PPS syndromes, including non-cardiac chest pain, irritable bowel syndrome (IBS) and chronic fatigue syndrome (CFS). Research indicates that PPS conditions share similar cognitive and behavioural responses to symptoms, such as avoidance and unhelpful beliefs. …”
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Evolving phenotypes of non-hospitalized patients that indicate long COVID by Hossein Estiri, Zachary H. Strasser, Gabriel A. Brat, Yevgeniy R. Semenov, The Consortium for Characterization of COVID-19 by EHR (4CE), Chirag J. Patel, Shawn N. Murphy

“…Among these phenotypes, a new diagnosis record for anosmia and dysgeusia (OR 2.60, 95% CI [1.94–3.46]), alopecia (OR 3.09, 95% CI [2.53–3.76]), chest pain (OR 1.27, 95% CI [1.09–1.48]), chronic fatigue syndrome (OR 2.60, 95% CI [1.22–2.10]), shortness of breath (OR 1.41, 95% CI [1.22–1.64]), pneumonia (OR 1.66, 95% CI [1.28–2.16]), and type 2 diabetes mellitus (OR 1.41, 95% CI [1.22–1.64]) is one of the most significant indicators of a past COVID-19 infection. …”
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Somatização na América Latina: uma revisão sobre a classificação de transtornos somatoformes, síndromes funcionais e sintomas sem explicação médica Somatization in Latin America: a... by Luís Fernando Tófoli, Laura Helena Andrade, Sandra Fortes

“…RESULTS: The analysis of 106 studies included in this review was divided into 15 categories: systematic reviews, conceptual reviews, prevalence, primary care, depression and anxiety, risk factors, violence, organic conditions, relationship with health care, ethnicity, culture-bound syndromes, chronic fatigue syndrome, fibromyalgia, body dysmorphic disorder, and conversion and dissociation. …”
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Fatigue and symptom-based clusters in post COVID-19 patients: a multicentre, prospective, observational cohort study by Merel E. B. Cornelissen, Lizan D. Bloemsma, Anouk W. Vaes, Nadia Baalbaki, Qichen Deng, Rosanne J. H. C. G. Beijers, Lieke C. E. Noij, Laura Houweling, Somayeh Bazdar, Martijn A. Spruit, Anke H. Maitland-van der Zee, on behalf of the P4O2 Consortium

“…This study aimed to determine the occurrence of fatigue and other symptoms, to assess how many patients meet the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) criteria, to identify symptom-based clusters within the P4O2 COVID-19 cohort and to compare these clusters with clusters in a ME/CFS cohort. …”
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Prevalence of and risk factors for severe cognitive and sleep symptoms in ME/CFS and MS by Vageesh Jain, Amit Arunkumar, Caroline Kingdon, Eliana Lacerda, Luis Nacul

“…Abstract Background There are considerable phenotypic and neuroimmune overlaps between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS). …”
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Investigating brain cortical activity in patients with post-COVID-19 brain fog by Grzegorz M. Wojcik, Oren Shriki, Oren Shriki, Lukasz Kwasniewicz, Andrzej Kawiak, Yarden Ben-Horin, Sagi Furman, Krzysztof Wróbel, Bernadetta Bartosik, Ewelina Panas

“…Brain fog is a kind of mental problem, similar to chronic fatigue syndrome, and appears about 3 months after the infection with COVID-19 and lasts up to 9 months. …”
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Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis by Krystyna Taylor, Matthew Pearson, Sayoni Das, Jason Sardell, Karolina Chocian, Steve Gardner

“…Studies have so far largely failed to identify genetic associations, the mechanisms behind the disease, or any common pathophysiology with other conditions such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) that present with similar symptoms. …”
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Differential Impacts of HHV-6A versus HHV-6B Infection in Differentiated Human Neural Stem Cells by Elham Bahramian, Elham Bahramian, Mercede Furr, Jerry T. Wu, Ruben Michael Ceballos, Ruben Michael Ceballos, Ruben Michael Ceballos, Ruben Michael Ceballos

“…Despite these viruses being implicated as causative agents in several nervous system disorders (e.g., multiple sclerosis, epilepsy, and chronic fatigue syndrome), the mechanisms of action and relative contributions of each virus to neurological dysfunction are unclear. …”
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Development and Validation of a Serologic Test Panel for Detection of Powassan Virus Infection in U.S. Patients Residing in Regions Where Lyme Disease Is Endemic by Angela M. Thomm, Anna M. Schotthoefer, Alan P. Dupuis, Laura D. Kramer, Holly M. Frost, Thomas R. Fritsche, Yvette A. Harrington, Konstance K. Knox, Sue C. Kehl

“…Testing could also benefit patients with tick exposure and unexplained neurologic symptoms and chronic fatigue syndrome (CFS) patients with known tick exposure. …”
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PLANT PIGMENTS IN PSYCHIATRY AND NEUROLOGY: HISTORICAL AND MODERN USES. PART II. A LITERATURE REVIEW WITH A CLINICAL CASE PRESENTATION by Roman A. Bekker, Yuriy V. Bykov

“…The results that we have presented in this review, in our opinion, can provide theoretical and practical grounds for the use of some of the plant pigments that we have reviewed there (for example, lycopene, lutein and zeaxanthin, resveratrol, etc.) in the combination treatment of chronic fatigue syndrome, of mild forms of anxiety and depressive disorders, mild cognitive impairment — especially in patients who refuse standard psychopharmacotherapy, or who do not tolerate it well. …”
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Epidemiology, pathophysiology, and classification of the neurological symptoms of post-COVID-19 syndrome by F.J. Carod-Artal, J.C. García-Moncó

“…The criteria differentiating post-COVID-19 syndrome from chronic fatigue syndrome or critical illness syndrome are ambiguous. …”
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Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial by Carl Johan Sundberg, Kenny A Rodriguez-Wallberg, John Pernow, Judith Bruchfeld, Xiaowei Zheng, Michael Runold, Peter Lindholm, Anders Kjellberg, Jan H Kowalski, Sergiu Catrina, Lina Abdel-Halim, Adrian Hassler, Sara El Gharbi, Sarah Al-Ezerjawi, Emil Boström, Koshiar Medson, Marcus Ståhlberg, Malin Nygren-Bonnier

“…In prospective studies, hyperbaric oxygen therapy (HBOT) has been suggested to be effective for the treatment of similar syndromes such as chronic fatigue syndrome and fibromyalgia. A case series has suggested positive effects of HBOT in long COVID-19. …”
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