RET Gene Fusions in Malignancies of the Thyroid and Other Tissues by Massimo Santoro, Marialuisa Moccia, Giorgia Federico, Francesca Carlomagno

“…Following the identification of the BCR-ABL1 (Breakpoint Cluster Region-ABelson murine Leukemia) fusion in chronic myelogenous leukemia, gene fusions generating chimeric oncoproteins have been recognized as common genomic structural variations in human malignancies. …”
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Molecular landscape and targeted therapy of acute myeloid leukemia by Runxia Gu, Xue Yang, Hui Wei

“…ATRA and imatinib have been successfully used in AML and chronic myelogenous leukemia, which proved that targeted therapy by identifying molecular lesions could improve leukemia outcomes. …”
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A novel five-way translocation t(7;11;9;22;<ul>9</ul>)(q22;q13;q34;q11.2;q34) involving Ph chromosome in a patient of chronic myeloid leukemia: a case report by Yokota Sho, Nakamura Yuichi, Bessho Masami

“…<p>Abstract</p> <p>About 5-10 % of chronic myelogenous leukemia (CML) patients show variant Philadelphia (Ph) translocations. …”
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Translational regulation of GPx-1 and GPx-4 by the mTOR pathway. by Emily N Reinke, Dede N Ekoue, Soumen Bera, Nadim Mahmud, Alan M Diamond

“…In order to expand upon this observation, the established chronic myelogenous leukemia cell lines KU812 and MEG-01 were treated with imatinib and the effect on several anti-oxidant proteins was determined. …”
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Design of nanofiber-based platform for leukemia stem cell capture. by Ruchi.

“…Chronic myelogenous leukemia (CML) is a cancer of hematopoietic cells. …”
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Chronic Myeloid Leukemia In a Pregnant Woman: A Case Report by Aytekin Tokmak, Ali irfan Guzel, Ahmet Yalinkaya

“…Our aim is to present a 37 weeks of pregnant woman with chronic myelogenous leukemia. A 27 Years in multigravi (gravida 5, parity: 4), at 37 weeks gestation was admitted with the diagnosis of painful pregnancy and CML. …”
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Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. by Jonathan W Kotula, Jinpeng Sun, Margie Li, Elizabeth D Pratico, Mark P Fereshteh, Douglas P Ahrens, Bruce A Sullenger, Jeffrey J Kovacs

“…Additionally, delivery of the β-arrestin 2-targeting aptamer into leukemia cells through coupling to a recently described cancer cell-specific delivery aptamer, inhibits multiple β-arrestin-mediated signaling pathways known to be required for chronic myelogenous leukemia (CML) disease progression, and impairs tumorigenic growth in CML patient samples. …”
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Non-small-cell lung cancer: molecular targeted therapy and personalized medicine &ndash; drug resistance, mechanisms, and strategies by Sechler M, Cizmic AD, Avasarala S, Van Scoyk M, Brzezinski C, Kelley N, Bikkavilli RK, Winn RA

“…Although targeted therapeutics have helped immensely in the treatment of several cancers, like chronic myelogenous leukemia, colon cancer, and breast cancer, the benefit of these agents in the treatment of lung cancer remains limited, in part due to the development of drug resistance. …”
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Is Imatinib Maintenance Required for Patients with Relapse Chronic Myeloid Leukemia Post-Transplantation Obtaining CMR? A Pilot Retrospective Investigation. by Hua Jin, Yiying Xiong, Jing Sun, Yu Zhang, Fen Huang, Hongsheng Zhou, Zhiping Fan, Dan Xu, Yongqiang Wei, Min Dai, Ru Feng, Qifa Liu

“…Imatinib can induce complete molecular remission (CMR) in relapse chronic myelogenous leukemia (CML) after allogeneic hematopoietic stem cell transplantation, but it is indefinite whether imatinib is required to maintain CMR. …”
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Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation. by Jamie G Bates, Julia Salzman, Damon May, Patty B Garcia, Gregory J Hogan, Martin McIntosh, Mark S Schlissel, Pat O Brown

“…Pre-B cells transformed with the viral oncogene v-Abl are suspended in an immortalized, cycling state that mimics leukemias with a BCR-ABL1 translocation, such as Chronic Myelogenous Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL). …”
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Long circulating lectin conjugated paclitaxel loaded magnetic nanoparticles: a new theranostic avenue for leukemia therapy. by Abhalaxmi Singh, Fahima Dilnawaz, Sanjeeb Kumar Sahoo

“…Amongst all leukemias, Bcr-Abl positive chronic myelogenous leukemia (CML) confers resistance to native drug due to multi drug resistance and also resistance to p53 and fas ligand pathways. …”
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The central nervous system leukemia: a clinical and pathological study by Maria Inês Vilhena Lana-Peixoto, Marco Aurélio Lana-Peixoto

“…Post-mortem clinical and pathological study of 18 cases of central nervous system leukemia showed that this complication occurred mostly in chronic myelogenous leukemia (38.8%). No diagnostic criteria was found. …”
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Infusão de leucócitos de dador após a transplantação alogénica de células estaminais. by J F de Lacerda

“…Most patients treated with donor leukocytes had a relapse of chronic myelogenous leukemia, which was successfully re-induced into remission. …”
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Synthesis, Cytotoxicity and Molecular Docking Study of Complexes Containing Thiazole Moiety by Mohammed Shafeeulla, Ganganaik Krishnamurthy, Halehatti S. Bhojynaik, Manjuraj T

“…The cytotoxic activity of the complexes and the uncoordinated ligand against human breast cancer (MCF-7) and chronic myelogenous leukemia cell line (human erythroleukemia) (K-562) cell lines exhibits good viability in the range of 50.16–55.16% at a concentration of >100-110 µg/mL as compared to the inhibition in the untreated cells. …”
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A New Method for Diagnosis and Predicting Blood Disorder and Cancer Using Artificial Intelligence (Artificial Neural Networks) by Mehrdad Payandeh, Mehrnoush Aeinfar, Vahid Aeinfar, Mohsen Hayati

“…This method was implemented to diagnose these disorder and cancer: Megaloblastic Anaemia, Thalassemia, Idiopathic thrombocytopenic pupura (ITP), Chronic myelogenous leukemia and Lymphoproliferative.…”
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Crystal Structure, Antibacterial and Cytotoxic Activities of a New Complex of Bismuth(III) with Sulfapyridine by Elene C. Pereira-Maia, Edmar Chartone-Souza, Mônica Bucciarelli-Rodriguez, Nelson G. Fernandes, Geandson C. Santos, Rodinei Augusti, Priscila P. Silva, Marina S. Franco, Ivana M. Marzano

“…The compound inhibits the growth of chronic myelogenous leukemia cells with an IC50 value of 44 μM whereas the free ligand has no effect up to 100 μM.…”
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Molecular approach to diagnose BCR/ABL negative chronic myeloproliferative neoplasms by Michelle Maccarini Barcelos, Maria Cláudia Santos-Silva

“…According to the World Health Organization myeloproliferative neoplasms are classified as: chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, primary myelofibrosis, chronic neutrophilic leukemia, chronic eosinophilic leukemia, hypereosinophilic syndrome, mast cell disease, and unclassifiable myeloproliferative neoplasms. …”
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Hemorrhagic and thrombotic complications in patients with myeloproliferative diseases by Carla Valladares Vignal, Dayse Maria Lourenço, Maria Aparecida Eiko Noguti, Maria de Lourdes Ferrari Chauffaille, José Kerbauy

“…PATIENTS: Eighteen patients with chronic myelogenous leukemia (CML), 5 with polycytemia vera (PV), 2 with essential thrombocytemia (ET) and 2 with idiopathic myelofibrosis (MF). …”
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Ponatinib-associated panniculitis: Case report and review of the literature by Daniel Antwi-Amoabeng, Joban Ghuman, Jasmine Ghuman, Bryce D. Beutler, Mark B. Ulanja, Kevin Kuriakose, Aaron Bowman

“…Ponatinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia and acute lymphoblastic leukemia. …”
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RNA binding profile analysis of N-acetyltransferase 10 in K562 cells by LI Gaoyuan, WANG Yanran, WANG Fang, YU Jia

“…Objective To delineate RNA binding profile of NAT10(N-acetyltransferase 10) in human chronic myelogenous leukemia cell line K562. Methods Enhanced UV crosslinking and immunoprecipitation (eCLIP) were used to capture the transcript collection bound by NAT10 in K562 cells. …”
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