Combination of a bronchogenic cyst in the thoracic spinal canal with chronic myelocytic leukemia by Zhang Hao, Li Hai-Feng, Duan Hai-Feng, Huang Ke-Feng, Tian Zhi-Hua

“…The presented case report describes an incredibly rare instance of an intramedullary bronchial cyst located in the thoracic spinal canal on the dorsal side of the spinal cord, which was observed in a patient with chronic myelogenous leukemia. A 29-year-old man presented with back pain for half a month, along with numbness and pain below the chest and ribs for 1 week. …”
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Acute obstructive suppurative pancreatic ductitis in pancreatic malignancies by Ryoko Shimizuguchi, Masataka Kikuyama, Terumi Kamisawa, Sawako Kuruma, Kazuro Chiba

“…Patients and methods We studied five patients with pancreatic ductal adenocarcinoma (PDAC) and one with chronic myelogenous leukemia (CML), who suffered from AOSPD. …”
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Novel therapies in breast cancer: what is new from ASCO 2008 by Lu Janice, Chu David

“…</p> <p>Since the advent of imatinib for the successful treatment of chronic myelogenous leukemia in the 2001, clinicians have been searching for comparable therapies that could be as efficacious and as tolerable. …”
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AKTIVITAS ANTI KANKER SENYAWA-SENYAWA KITOOLIGOMER [Anti Cancer Activity of Chitooligomers] by Dahrul Syah2), Arief B. Witarto3), Fransiska Zakaria2), Sri Wahyuni1), Maggy T. Suhartono2)

“…The effect of this samples on cancer cells was evaluated using K562 cells (chronic myelogenous leukemia) and investigated after being treated with MTT (3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide). …”
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Chromosomal Translocations Detection in Cancer Cells Using Chromosomal Conformation Capture Data by Muhammad Muzammal Adeel, Khaista Rehman, Yan Zhang, Yibeltal Arega, Guoliang Li

“…This study used Hi-C data of cancerous cell lines, namely lung cancer (A549), Chronic Myelogenous Leukemia (K562), and Acute Monocytic Leukemia (THP-1), to detect the translocations. …”
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Mesenchymal stem cells from patients with chronic myeloid leukemia do not express BCR-ABL and have absence of chimerism after allogeneic bone marrow transplant by R.C.V. Carrara, M.D. Orellana, A.M. Fontes, P.V.B. Palma, S. Kashima, M.R. Mendes, M.A. Coutinho, J.C. Voltarelli, D.T. Covas

“…Dysregulated hematopoiesis occurs in chronic myelogenous leukemia (CML), being caused at least in part by abnormalities in the hematopoietic progenitors. …”
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Imatinib and nilotinib inhibit hematopoietic progenitor cell growth, but do not prevent adhesion, migration and engraftment of human cord blood CD34+ cells. by Ludovic Belle, France Bruck, Jacques Foguenne, André Gothot, Yves Beguin, Frédéric Baron, Alexandra Briquet

“…Studies in healthy volunteers and patients with chronic myelogenous leukemia or gastrointestinal stromal tumors have shown that therapeutic doses of nilotinib deliver drug levels similar to those of imatinib. …”
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Analysis of the expression correlation trithorax group protein core components DPY30 and ASH2L by WEN Chang, LI Liang, SHU Peng-cheng, QIANG Bo-qin, PENG Xiao-zhong

“…Methods Northern blot was used to detect the expression of ASH2L and DPY30 in various human tissues and the trend of ASH2L and DPY30 expression during the differentiation of human chronic myelogenous leukemia (K562) cells induced by PMA. Western blot and RT-qPCR were used to detect the expression of protein and RNA of TrxG core components in the cerebral cortex of ASH2L conditional knockout mouse; IGV software was used to visually analyze the distribution of ASH2L and H3K4me3 on ASH2L and DPY30 gene chromatin in ChIP-seq results of mouse cerebral cortex. …”
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Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells. by Emmanuelle Supper, Suhail Tahir, Takahiko Imai, Joe Inoue, Nagahiro Minato

“…Expression of the Bcr-Abl fusion gene in hematopoietic progenitor cells (HPCs) results in the development of chronic myelogenous leukemia (CML), for which hematopoietic microenvironment plays an important role. …”
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Novel 1, 1-dimethyl-3-phenyl-3-(5-phenyl-1, 3, 4- thiadiazol-2-yl) urea derivative has potential antiproliferative activity against human leukemia cell lines - K562 by Khemkaran Ahirwar, Sanmati K. Jain, Bholenath Tamrakar

“…The antiproliferative activities of these compounds wee evaluated against a Cytotoxicity analysis of compounds against leukemia cell line -K562 organism homo sapiens(human) organ bone – marrow, tissue - lymphoblast, disease – chronic myelogenous leukemia(CML) one human tumor cell lines(K562) by applying the MTT colorimetric assay. …”
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A Modified Electrochemical Sensor Based on N,S-Doped Carbon Dots/Carbon Nanotube-Poly(Amidoamine) Dendrimer Hybrids for Imatinib Mesylate Determination by Maryam Saleh Mohammadnia, Hossein Roghani-Mamaqani, Masoumeh Ghalkhani, Salar Hemmati

“…Imatinib mesylate, an anticancer drug, is prescribed to treat gastrointestinal stromal tumors and chronic myelogenous leukemia. A hybrid nanocomposite of N,S-doped carbon dots/carbon nanotube-poly(amidoamine) dendrimer (N,S-CDs/CNTD) was successfully synthesized and used as a significant modifier to design a new and highly selective electrochemical sensor for the determination of imatinib mesylate. …”
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Emerging Data on the Safety and Efficacy of Ripretinib for the Treatment of Gastrointestinal Stromal Tumors by Thirasastr P, Somaiah N

“…All three of these drugs were serendipitously found to have activity in GIST, starting with imatinib, which was formulated for its ability to inhibit BCR-ABL in chronic myelogenous leukemia. Ripretinib is a drug that was specifically developed as a more potent KIT tyrosine kinase inhibitor (TKI), with broad-spectrum activity against the mutations encountered in GIST. …”
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Paraneoplastic Amyotrophic Lateral Sclerosis: Case Series and Literature Review by Zhao Yang, Lu He, Manli Ren, Yizhou Lu, Huanyu Meng, Dou Yin, Sheng Chen, Qinming Zhou

“…We also reported two ALS patients with renal clear cell carcinoma and chronic myelogenous leukemia. No positive paraneoplastic antibodies were detected in either the serum or the cerebrospinal fluid of the two patients, and their clinical symptoms progressed slowly after tumor treatment. …”
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Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia by Judith E Karp, Jeffrey E Lancet

“…Tipifarnib is an orally bioavailable, nonpeptidomimetic methylquinolone FTI that has exhibited clinical activity in patients with myeloid malignancies including elderly adults with acute myelogenous leukemia (AML) who are not candidates for traditional cytotoxic chemotherapy, patients with high-risk myelodysplasia, myeloproliferative disorders, and imatinib-resistant chronic myelogenous leukemia. Because of its relatively low toxicity profile, tipifarnib provides an important alternative to traditional cytotoxic approaches for elderly patients who are not likely to tolerate or even benefit from aggressive chemotherapy. …”
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Linear programming based computational technique for leukemia classification using gene expression profile. by Mahwish Ilyas, Khalid Mahmood Aamir, Sana Manzoor, Mohamed Deriche

“…There are four types of leukemia, namely acute lymphocytic leukemia, acute myelogenous leukemia, chronic lymphocytic in extracting, and chronic myelogenous leukemia. Recognizing these cancerous development cells is often done via manual analysis of microscopic images. …”
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Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. by Yuki Ishii, May Keu Nhiayi, Edison Tse, Jonathan Cheng, Michele Massimino, Donald L Durden, Paolo Vigneri, Jean Y J Wang

“…We show here that KOSR has pro-survival activity in chronic myelogenous leukemia (CML) cells transformed by the BCR-ABL oncogene. …”
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Cancer risks in a population-based study of agricultural workers: results from the Taiwan’s Farmers and Health Cohort study by Wei-Liang Chen, Gwan-Ling Lin, Yu-Jen Lin, Ting-Yao Su, Chung-Ching Wang, Wei-Te Wu

“…The study found that male farmers had an increased cancer risk, including lymphocytic leukemia, chronic myelogenous leukemia, non-Hodgkin’s lymphoma (NHL), oral cancer, lip cancer, esophagus cancer, rectum and rectosigmoid junction cancer, liver and intrahepatic bile duct cancer, lung cancer, trachea and bronchi cancer, and other non-melanoma skin cancer, even when considering the latency period. …”
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OUR EXPERIENCE WITH TREATMENT OF CHRONIC MYELOID LEUKEMIA WITH IMATINIB MESYLATE by Mojca Modic, Matjaž Sever

“…Imatinib mesylate is an Abl kinase inhibitor capable of producing a sustained complete molecular response in chronic myelogenous leukemia (CML). It is effective in all three phases of CML with the longest response in the chronic phase. …”
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Summary of 615 patients of chronic myeloid leukemia in Shanghai from 2001 to 2006 by Shen Zhi-Xiang, Chen Yu, Zhang Li, Wang Li, Zhou Li, Xu Zi-Zhen, Yao Yu, Wang Yan-Yan, Wang Ai-Hua, Hu Jiong, Li Jun-Min

“…<p>Abstract</p> <p>Background</p> <p>To retrospectively review the incidence, treatment efficacy, we followed up newly diagnosed chronic myelogenous leukemia (CML) patients residing in Shanghai during 2001-2006.…”
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Classification of Effective Cells in Diagnosis of Chronic Myeloid Leukemia (CML) Using Semi-automatic Image Processing of Microscopic Images by Narjes Ghane, Alireza Vard, Ardeshir Talebi, Pardis Nematollahy

“…Background: Chronic myelogenous leukemia (CML) is a type of blood cancers that usually occur in adults. …”
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