Efficacy of combined strategies of physical activity, diet and sleep disorders as treatment in patients with chronic shoulder pain. A systematic review by Dina Hamed Hamed, Filip Struyf, Leo Pruimboom, Leo Pruimboom, Santiago Navarro-Ledesma, Santiago Navarro-Ledesma

“…We searched six databases Pubmed, Cochrane Library, Web of Science, CINAHL, Sportdiscus and Scopus, using the keywords “shoulder pain,” “fasting,” “physical therapy modalities,” “rehabilitation,” “exercise,” “circadian clocks,” and “chronic pain” to select randomized controlled clinical trials conducted in humans and written in English. …”
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miR-263b Controls Circadian Behavior and the Structural Plasticity of Pacemaker Neurons by Regulating the LIM-Only Protein Beadex by Xiaoge Nian, Wenfeng Chen, Weiwei Bai, Zhangwu Zhao, Yong Zhang

“…<b>: </b>Circadian clocks drive rhythmic physiology and behavior to allow adaption to daily environmental changes. …”
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Las mil y una noches de la melatonina by Harold Felipe Saavedra-López, María Juliana García-Pérez, Juan Manuel Arteaga-Díaz

“…Metodología: revisión bibliográfica en la base de datos PubMed y Scopus utilizando los términos MeSH: “melatonin”, “circadian clocks”, “circadian rhythm”, “cancer”, “oxidative stress”. …”
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Streamlined single-molecule RNA-FISH of core clock mRNAs in clock neurons in whole mount Drosophila brains by Ye Yuan, Marc-Antonio Padilla, Dunham Clark, Swathi Yadlapalli, Swathi Yadlapalli, Swathi Yadlapalli

“…Circadian clocks are ∼24-h timekeepers that control rhythms in almost all aspects of our behavior and physiology. …”
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Chronic circadian desynchronization of feeding-fasting rhythm generates alterations in daily glycemia, LDL cholesterolemia and microbiota composition in mice by Laura Lucía Trebucq, Melisa Luciana Lamberti, Rosana Rota, Ignacio Aiello, Cristina Borio, Marcos Bilen, Diego Andrés Golombek, Diego Andrés Golombek, Santiago Andrés Plano, Santiago Andrés Plano, Juan José Chiesa

“…Timing of food intake and fasting periods provide strong signals for peripheral circadian clocks regulating nutrient assimilation, glucose, and lipid metabolism. …”
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12-week melatonin administration had no effect on diabetes risk markers and fat intake in overweight women night workers by Carlos Alberto Rodrigues de Sousa, Carlos Alberto Rodrigues de Sousa, Luciana Fidalgo Nogueira, José Cipolla-Neto, Claudia Roberta de Castro Moreno, Claudia Roberta de Castro Moreno, Elaine Cristina Marqueze, Elaine Cristina Marqueze

“…IntroductionInteractions between circadian clocks and key mediators of chronic low-grade inflammation associated with fat consumption may be important in maintaining metabolic homeostasis and may pose a risk for the development of obesity-associated comorbidities, especially type 2 diabetes (T2DM).ObjectiveThe aims of the present study were to evaluate the effects of melatonin administration on diabetes risk markers according to dietary lipid profile (pro-inflammatory versus anti-inflammatory) in excessive weight night workers, and to determine the effect of administration on fat consumption profile.MethodsA randomized, controlled, double-blind, crossover clinical trial involving 27 nursing professionals working permanent night shifts under a 12×36-hour system. …”
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Exposure to artificial light at night mediates the locomotion activity and oviposition capacity of Dastarcus helophoroides (Fairmaire) by Xiang-lan Jiang, Zhe Ren, Xiao-xia Hai, Ling Zhang, Zhi-gang Wang, Fei Lyu

“…Light entrains the endogenous circadian clocks of organisms to synchronize their behavioral and physiological rhythms with the natural photoperiod. …”
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Multicentre, interventional, single-arm study protocol of telemonitored circadian rhythms and patient-reported outcomes for improving mFOLFIRINOX safety in patients with pancreatic... by Pascal Hammel, Rene Adam, Francis Levi, Amal Attari, Mohamed Bouchahda, Ayhan Ulusakarya, Anne Thirot-Bidault, Rachel Bossevot, Richard Tuligenga

“…Introduction Circadian clocks regulate cellular proliferation and drug effects. …”
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Time-Dependent Efficacy of Checkpoint Inhibitor Nivolumab: Results from a Pilot Study in Patients with Metastatic Non-Small-Cell Lung Cancer by Abdoulaye Karaboué, Thierry Collon, Ida Pavese, Viviane Bodiguel, Joel Cucherousset, Elda Zakine, Pasquale F. Innominato, Mohamed Bouchahda, René Adam, Francis Lévi

“…Nivolumab targets T(CD8) cells, the functions, and trafficking of which are regulated by circadian clocks, hence suggesting possible daily changes in nivolumab’s efficacy. …”
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