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Clinical experience with the AKT1 inhibitor miransertib in two children with PIK3CA-related overgrowth syndrome
Published 2021-02-01“…Results Two patients, one with CLOVES variant (P1) and one with facial infiltrating lipomatosis and hemimegalencephaly (P2), were commenced on miransertib treatment on a compassionate use basis. …”
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In vitro anti-Helicobacter pylori activity and the underlining mechanism of an empirical herbal formula – Hezi Qingyou
Published 2024-02-01“…Our team proposed a Hezi Qingyou Formula (HZQYF), composed of Chebulae Fructus, Ficus hirta Vahl and Cloves, and studied its anti-H. pylori activity and mechanism.MethodsChemical components of HZQYF were studied using UHPLC–MS/MS and HPLC. …”
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French national diagnosis and care protocol (PNDS, protocole national de diagnostic et de soins): cystic lymphatic malformations
Published 2023-01-01“…A biopsy, coupled to a blood sample, can also be used for molecular biology analyses, to search for activating mutations of the PIK3CA gene, particularly with LM integrating in a syndromic form (CLOVES or Klippel-Trenaunay syndrome) but also in certain isolated (or common) LMs. …”
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Vascular Birthmarks as a Clue for Complex and Syndromic Vascular Anomalies
Published 2021-10-01“…Diffuse capillary malformation with overgrowth, Klippel–Trenaunay syndrome, CLAPO syndrome, CLOVES syndrome, and megalencephaly-capillary malformation belong to the PIK3CA-related overgrowth. …”
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Production of Virus-Free Garlic Plants through Somatic Embryogenesis
Published 2021-04-01“…The present study was conducted to establish a protocol for the regeneration of virus-free garlic plants through somatic embryogenesis of two Croatian garlic ecotypes. Basal parts of cloves from mother plants were cultured on a full Murashige and Skoog (MS) or modified MS medium (¼ of KNO<sub>3</sub> and NH<sub>4</sub>NO<sub>3</sub> and 2xMgSO<sub>4</sub>) containing 0.1 mg L<sup>−1</sup> 2,4-dichlorophenoxyacetic acid (2,4-D) or 1 mg L<sup>−1</sup> 2,4-D + 0.5 mg L<sup>−1</sup> kinetin (Kin) and representing four different treatments. …”
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Effect of Duration of High-Grain Feeding on Chewing, Feeding Behavior, and Salivary Composition in Cows with or without a Phytogenic Feed Supplement
Published 2022-08-01“…This experiment primarily aimed to assess the effects of the duration of an HG diet on the chewing, eating, and lying behavior and salivation dynamics in a control group (CON) and a group of cows receiving a phytogenic feed supplement (TRT) at 0.04% (DM basis), which included L-menthol, thymol, eugenol, mint oil, and cloves powder. The experiment was a crossover design with nine non-lactating cows, and two experimental periods with an intermediate washout of four weeks. …”
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