Impacts of ZnO as a nanofertilizer on fenugreek: some biochemical parameters and SCoT analysis by Doaa E. Elsherif, Eman Abd-ElShafy, Asmaa M. Khalifa

“…In addition, genetic variation measure using start codon targeted (SCoT) markers revealed that ZnO NP treatments exhibited limited genetic variation. …”
Get full text

Generation of human induced pluripotent stem cell line (MUi033-A) from a male with homozygous for Hemoglobin E by Pirut Tong-ngam, Wasinee Wongkummool, Phitchapa Pongpaksupasin, Nongnaphat Rawara, Duangnapa Kovanich, Narisorn Kitiyanant, Thongperm Munkongdee, Kittiphong Paiboonsukwong, Suthat Fucharoen, Alisa Tubsuwan

“…Hemoglobin E (HbE), a common variant in Southeast Asian populations, results from a G to A substitution at codon 26 of the HBB gene, causing abnormal Hb and mild β-thalassemia-like symptoms. …”
Get full text

The complete mitochondrial genome of Goniurosaurus varius (Squamata: Eublepharidae) by Zhengyan Zhou, Lin Ding, Ziyi Liu, Longming Fu, Lanying Xu, Lin Feng, Sufan Yu, Pipeng Li, Yu Zhou

“…Seven protein-coding genes (COX2, COX3, ND1, ND2, ND3, ND4 and CYTB) exhibit incomplete stop codon ‘T.’ Phylogenetic analysis revealed the monophyly of Goniurosaurus and Eublepharidae and suggested that G. varius is closely related to the lineage composed of G. luii and G. liboensis. …”
Get full text

Emerging Role of SMILE in Liver Metabolism by Nanthini Sadasivam, Kamalakannan Radhakrishnan, Hueng-Sik Choi, Don-Kyu Kim

“…SMILE has two isoforms, a small and long isoform, resulting from alternative usage of the initiation codon. Interestingly, although SMILE can homodimerize similar to other bZIP proteins, it cannot bind to DNA. …”
Get full text

Detection of fluoroquinolone resistance by mutation in gyrA gene of Campylobacter spp. isolates from broiler and laying (Gallus gallus domesticus) hens,from Rio de Janeiro State, B... by Beatriz da Silva Frasao, Valéria Medeiros, André Victor Barbosa, Waldemir Silva de Aguiar, Felipe Faccini dos Santos, Dayse Lima da Costa Abreu, Maysa Mandetta Clementino, Maria Helena Cosendey de Aquino

“…All strains presented the QRDR mutation in the gyrA gene at codon 86 (Thr-86-Ile), which confers resistance to fluoroquinolones. …”
Get full text

Interrogating 1000 insect genomes for NUMTs: A risk assessment for estimates of species richness. by Paul D N Hebert, Dan G Bock, Sean W J Prosser

“…Two thirds of COI NUMTs possessed an IPSC (indel and/or premature stop codon) allowing their recognition and exclusion from downstream analyses. …”
Get full text

Complete chloroplast genome sequence of Lens ervoides and comparison to Lens culinaris by Nurbanu Tayşi, Yasin Kaymaz, Duygu Ateş, Hatice Sari, Cengiz Toker, M. Bahattin Tanyolaç

“…Analysis of relative synonymous codon usage showed that certain genes, psbN, psaI, psbI, psbE, psbK, petD, and ndhC, preferred using biased codons more often and therefore might have elevated expression and translation efficiencies. …”
Get full text

Perry syndrome with a novel mutation and a rare presentation: First report from India by Pramod Krishnan, Gosala R K. Sarma, Uday Murgod, Murali Srinivas, Ajit K Roy

“…A heterozygous missense variation in Exon 2 of the DCTN1 gene that results in the substitution of Proline for Alanine at codon 45 (pA45P) was detected. This variant was not detected in his clinically unaffected brother. …”
Get full text

Prl and B4GALT-1 gene polymorphism and their association with milk production traits in crossbred cattle of Kerala by TINA SADAN, JAMUNA VALSALAN, THIRUPATHY VENKETACHALAPATHY, T V ARAVINDAKSHAN

“…Sequencing revealed a nonsynonymous single nucleotide variation in c.521T>C in exon 2 of B4GALT-1, resulted in an amino acid substitution of methionine to threonine due to a codon change of ATG to ACG. Different genetic variants of B4GALT-1 was significantly associated with 305 days milk yield and protein percent. …”
Get full text

ATXN2 is a target of N-terminal proteolysis. by Monika Chitre, Patrick Emery

“…However, this sequence is not required for cleavage of a short ATXN2 isoform produced from an alternative start codon located just upstream of the CAG repeats encoding the polyQ domain. …”
Get full text

Genetic Characteristic and Global Transmission of Influenza A H9N2 Virus by Mingda Hu, Yuan Jin, Jing Zhou, Zhisong Huang, Beiping Li, Wei Zhou, Hongguang Ren, Junjie Yue, Long Liang

“…Due to the distribution of sampling locations, we named the three lineages as Worldwide lineage, Asia-Africa lineage, and China lineage. Codon usage analysis and selective positive site analysis of the lineages further showed the lineage-specific evolution of the virus. …”
Get full text

Comparative Diagnostic Accuracy of Mean and Lowest Cycle Threshold Levels in Xpert MTB/RIF Assay and Molecular Epidemiology of Missing Probes In Rifampicin Re...

“…Background: The comparative diagnostic accuracy of mean and lowest Ct values needs to be evaluated for the assessment of mycobacterial burden in tubercular cases. Mutation in any codon of 81 base-pair core regions prevents the hybridization of one or more of five overlapping Probes A-Ein Xpert MTB/RIF assay indicated by “missing probe. …”
Get full text

Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling by Zane A Jaafar, Akihiro Oguro, Yoshikazu Nakamura, Jeffrey S Kieft

“…We discovered that eIF1A is necessary for efficient activity where it stabilizes tRNA binding and inspects the codon-anticodon interaction, especially important in the IRES’ eIF2-independent mode. …”
Get full text

The Genetic Code Assembles via Division and Fusion, Basic Cellular Events by Michael Yarus

“…Code fusion can unite multiple codon assignment mechanisms. However, via code division and fusion, an SGC can emerge from a single primary origin via familiar cellular events.…”
Get full text

Strength and Regulation of Seven rRNA Promoters in Escherichia coli. by Michihisa Maeda, Tomohiro Shimada, Akira Ishihama

“…For application of this promoter assay vector for measurement of the rRNA operon promoters devoid of the signal for translation, a synthetic SD sequence was added at the initiation codon of the reporter GFP gene, and then approximately 500 bp-sequence upstream each 16S rRNA was inserted in front of this SD sequence. …”
Get full text

Immunoinformatics guided design of a next generation epitope-based vaccine against Kaposi Sarcoma by Hammadul Hoque, Sumaiya, Mahmudul Hasan, Md Mashiur Rahaman, G.M. Nurnabi Azad Jewel, Shamsul H. Prodhan

“…Docking experiments revealed that the vaccination can make stable interactions with Toll-Like Receptor. Codon optimization and insertion into the cloning vector revealed that the newly designed vaccine candidate could be proficiently expressed in the E. coli system. …”
Get full text

Case of mucinous adenocarcinoma of the lung associated with congenital pulmonary airway malformation in a neonate by Juneyoug Koh, Euiseok Jung, Se Jin Jang, Dong Kwan Kim, Byong Sop Lee, Ki-Soo Kim, Ellen Ai-Rhan Kim

“…KRAS sequencing revealed a somatic mutation in Codon12 (GGT → GAT), suggesting the development of a mucinous adenocarcinoma in the background of mucinous metaplasia. …”
Get full text

Generation of NANOS3-mCherry reporter human embryonic stem cell line SYSUe-009-A using CRISPR/Cas9 by Ruirui Guo, Simin Yuan, Bing Li, Jichang Wang, Chuanbo Sun

“…This hESC line with an mCherry knock-in at the site before NANOS3′s stop codon serves as a useful tool to learn human PGC specification.…”
Get full text

Interrogating 1000 insect genomes for NUMTs: A risk assessment for estimates of species richness by Paul D. N. Hebert, Dan G. Bock, Sean W. J. Prosser

“…Two thirds of COI NUMTs possessed an IPSC (indel and/or premature stop codon) allowing their recognition and exclusion from downstream analyses. …”
Get full text

A Homolog of the Arabidopsis TIME FOR COFFEE Gene Is Involved in Nonhost Resistance to Wheat Stem Rust in Brachypodium distachyon by Rafael Della Coletta, Anastasiya A. Lavell, David F. Garvin

“…Through bioinformatic analysis, a 1-bp deletion in the mutant genotype was identified that introduces a premature stop codon in the gene Bradi1g24100, which is a homolog of the Arabidopsis thaliana gene TIME FOR COFFEE (TIC). …”
Get full text