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2461
Impacts of ZnO as a nanofertilizer on fenugreek: some biochemical parameters and SCoT analysis
Published 2023-05-01“…In addition, genetic variation measure using start codon targeted (SCoT) markers revealed that ZnO NP treatments exhibited limited genetic variation. …”
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2462
Generation of human induced pluripotent stem cell line (MUi033-A) from a male with homozygous for Hemoglobin E
Published 2023-12-01“…Hemoglobin E (HbE), a common variant in Southeast Asian populations, results from a G to A substitution at codon 26 of the HBB gene, causing abnormal Hb and mild β-thalassemia-like symptoms. …”
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2463
The complete mitochondrial genome of Goniurosaurus varius (Squamata: Eublepharidae)
Published 2023-11-01“…Seven protein-coding genes (COX2, COX3, ND1, ND2, ND3, ND4 and CYTB) exhibit incomplete stop codon ‘T.’ Phylogenetic analysis revealed the monophyly of Goniurosaurus and Eublepharidae and suggested that G. varius is closely related to the lineage composed of G. luii and G. liboensis. …”
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2464
Emerging Role of SMILE in Liver Metabolism
Published 2023-02-01“…SMILE has two isoforms, a small and long isoform, resulting from alternative usage of the initiation codon. Interestingly, although SMILE can homodimerize similar to other bZIP proteins, it cannot bind to DNA. …”
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2465
Detection of fluoroquinolone resistance by mutation in gyrA gene of Campylobacter spp. isolates from broiler and laying (Gallus gallus domesticus) hens,from Rio de Janeiro State, B...
Published 2015-11-01“…All strains presented the QRDR mutation in the gyrA gene at codon 86 (Thr-86-Ile), which confers resistance to fluoroquinolones. …”
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2466
Interrogating 1000 insect genomes for NUMTs: A risk assessment for estimates of species richness.
Published 2023-01-01“…Two thirds of COI NUMTs possessed an IPSC (indel and/or premature stop codon) allowing their recognition and exclusion from downstream analyses. …”
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2467
Complete chloroplast genome sequence of Lens ervoides and comparison to Lens culinaris
Published 2022-09-01“…Analysis of relative synonymous codon usage showed that certain genes, psbN, psaI, psbI, psbE, psbK, petD, and ndhC, preferred using biased codons more often and therefore might have elevated expression and translation efficiencies. …”
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2468
Perry syndrome with a novel mutation and a rare presentation: First report from India
Published 2022-01-01“…A heterozygous missense variation in Exon 2 of the DCTN1 gene that results in the substitution of Proline for Alanine at codon 45 (pA45P) was detected. This variant was not detected in his clinically unaffected brother. …”
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2469
Prl and B4GALT-1 gene polymorphism and their association with milk production traits in crossbred cattle of Kerala
Published 2021-04-01“…Sequencing revealed a nonsynonymous single nucleotide variation in c.521T>C in exon 2 of B4GALT-1, resulted in an amino acid substitution of methionine to threonine due to a codon change of ATG to ACG. Different genetic variants of B4GALT-1 was significantly associated with 305 days milk yield and protein percent. …”
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2470
ATXN2 is a target of N-terminal proteolysis.
Published 2023-01-01“…However, this sequence is not required for cleavage of a short ATXN2 isoform produced from an alternative start codon located just upstream of the CAG repeats encoding the polyQ domain. …”
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2471
Genetic Characteristic and Global Transmission of Influenza A H9N2 Virus
Published 2017-12-01“…Due to the distribution of sampling locations, we named the three lineages as Worldwide lineage, Asia-Africa lineage, and China lineage. Codon usage analysis and selective positive site analysis of the lineages further showed the lineage-specific evolution of the virus. …”
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2472
Comparative Diagnostic Accuracy of Mean and Lowest Cycle Threshold Levels in Xpert MTB/RIF Assay and Molecular Epidemiology of Missing Probes In Rifampicin Re...
Published 2021-01-01“…Background: The comparative diagnostic accuracy of mean and lowest Ct values needs to be evaluated for the assessment of mycobacterial burden in tubercular cases. Mutation in any codon of 81 base-pair core regions prevents the hybridization of one or more of five overlapping Probes A-Ein Xpert MTB/RIF assay indicated by “missing probe. …”
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2473
Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
Published 2016-12-01“…We discovered that eIF1A is necessary for efficient activity where it stabilizes tRNA binding and inspects the codon-anticodon interaction, especially important in the IRES’ eIF2-independent mode. …”
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2474
The Genetic Code Assembles via Division and Fusion, Basic Cellular Events
Published 2023-10-01“…Code fusion can unite multiple codon assignment mechanisms. However, via code division and fusion, an SGC can emerge from a single primary origin via familiar cellular events.…”
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2475
Strength and Regulation of Seven rRNA Promoters in Escherichia coli.
Published 2015-01-01“…For application of this promoter assay vector for measurement of the rRNA operon promoters devoid of the signal for translation, a synthetic SD sequence was added at the initiation codon of the reporter GFP gene, and then approximately 500 bp-sequence upstream each 16S rRNA was inserted in front of this SD sequence. …”
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2476
Immunoinformatics guided design of a next generation epitope-based vaccine against Kaposi Sarcoma
Published 2022-01-01“…Docking experiments revealed that the vaccination can make stable interactions with Toll-Like Receptor. Codon optimization and insertion into the cloning vector revealed that the newly designed vaccine candidate could be proficiently expressed in the E. coli system. …”
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2477
Case of mucinous adenocarcinoma of the lung associated with congenital pulmonary airway malformation in a neonate
Published 2018-01-01“…KRAS sequencing revealed a somatic mutation in Codon12 (GGT → GAT), suggesting the development of a mucinous adenocarcinoma in the background of mucinous metaplasia. …”
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2478
Generation of NANOS3-mCherry reporter human embryonic stem cell line SYSUe-009-A using CRISPR/Cas9
Published 2023-03-01“…This hESC line with an mCherry knock-in at the site before NANOS3′s stop codon serves as a useful tool to learn human PGC specification.…”
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2479
Interrogating 1000 insect genomes for NUMTs: A risk assessment for estimates of species richness
Published 2023-01-01“…Two thirds of COI NUMTs possessed an IPSC (indel and/or premature stop codon) allowing their recognition and exclusion from downstream analyses. …”
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2480
A Homolog of the Arabidopsis TIME FOR COFFEE Gene Is Involved in Nonhost Resistance to Wheat Stem Rust in Brachypodium distachyon
Published 2021-11-01“…Through bioinformatic analysis, a 1-bp deletion in the mutant genotype was identified that introduces a premature stop codon in the gene Bradi1g24100, which is a homolog of the Arabidopsis thaliana gene TIME FOR COFFEE (TIC). …”
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