A single sequence context cannot satisfy all non-AUG initiator codons in yeast^† by Wang Tzu-Ling, Lin Chen-Huan, Chen Shun-Jia, Chang Chia-Pei, Wang Chien-Chia

“…<p>Abstract</p> <p>Background</p> <p>Previous studies in <it>Saccharomyces cerevisiae </it>showed that <it>ALA1 </it>(encoding alanyl-tRNA synthetase) and <it>GRS1 </it>(encoding glycyl-tRNA synthetase) respectively use ACG and TTG as their alternative translation initiator codons. To explore if any other non-ATG triplets can act as initiator codons in yeast, <it>ALA1 </it>was used as a reporter for screening.…”
Get full text

Evolution and codon usage bias of mitochondrial and nuclear genomes in <i>Aspergillus</i> section <i>Flavi</i> by Miya Hugaboom, Elizabeth Anne Hatmaker, Abigail L LaBella, Antonis Rokas

Get full text

Codon-mRNA prediction using deep optimal neurocomputing technique (DLSTM-DSN-WOA) and multivariate analysis by Zena A. Kadhuim, Samaher Al-Janabi

Subjects: Get full text

Correction: Multiparameter RNA and Codon Optimization: A Standardized Tool to Assess and Enhance Autologous Mammalian Gene Expression

Get full text

Codon Usage Analyses Reveal the Evolutionary Patterns among Plastid Genes of Saxifragales at a Larger-Sampling Scale by De Bi, Shiyun Han, Jun Zhou, Maojin Zhao, Sijia Zhang, Xianzhao Kan

Subjects: Get full text

First report from Turkey of a rare frameshift mutation [codons 9/10 (+T)] in the beta-globin gene by Ramazan Güneşaçar, M. Murat Çelik

Get full text

Genetic diversity and structure of Capsicum annuum as revealed by start codon targeted and directed amplified minisatellite DNA markers by David O. Igwe, Celestine A. Afiukwa, George Acquaah, George N. Ude

“…Therefore, we comparatively explored the effectiveness of start codon targeted (SCoT) and directed amplified minisatellite DNA (DAMD) markers for diversity analysis of the accessions. …”
Get full text

Efficient Pseudotyping of Different Retroviral Vectors Using a Novel, Codon-Optimized Gene for Chimeric GALV Envelope by Manuela Mirow, Lea Isabell Schwarze, Boris Fehse, Kristoffer Riecken

“…In order to improve expression efficiency and vector titers, we developed a codon-optimized (co) variant of GALV-C_4070A (coGALV-Env). …”
Get full text

RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies by Fiona Tulloch, Nicky J Atkinson, David J Evans, Martin D Ryan, Peter Simmonds

Subjects: Get full text

Systematic evaluation of TP53 codon 72 polymorphism associated with onset and progression of oral potentially malignant disorders by Huangkai Li, Yu Liu, Shanxin Zhou, Qin Zhou, Xi Yang

“…Methods A systematic evaluation was conducted to identify all eligible case–control studies on the association of TP53 codon 72 polymorphism with both onset and progression of OPMD. …”
Get full text

The highly conserved codon following the slippery sequence supports -1 frameshift efficiency at the HIV-1 frameshift site. by Suneeth F Mathew, Caillan Crowe-McAuliffe, Ryan Graves, Tony S Cardno, Cushla McKinney, Elizabeth S Poole, Warren P Tate

“…This GGG codon is highly conserved in natural isolates of HIV. …”
Get full text

Investigating REPAIRv2 as a Tool to Edit <i>CFTR</i> mRNA with Premature Stop Codons by Raffaella Melfi, Patrizia Cancemi, Roberta Chiavetta, Viviana Barra, Laura Lentini, Aldo Di Leonardo

Subjects: “…premature termination codons (PTCs)…”
Get full text

Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation by Federica Corrao, Maria Grazia Zizzo, Marco Tutone, Raffaella Melfi, Ignazio Fiduccia, Pietro Salvatore Carollo, Aldo Di Leonardo, Gaetano Caldara, Riccardo Perriera, Andrea Pace, Beatrice Belmonte, Selene Sammataro, Ivana Pibiri, Laura Lentini

Subjects: Get full text

Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor‐alpha protein in breast cancer cells by Léa Clusan, Frederic Percevault, Emmanuelle Jullion, Pascale Le Goff, Christophe Tiffoche, Tamara Fernandez‐Calero, Raphaël Métivier, Monica Marin, Farzad Pakdel, Denis Michel, Gilles Flouriot

Subjects: Get full text

Synonymous Codon Usage Bias in the Chloroplast Genomes of 13 Oil-Tea Camellia Samples from South China by Jing Chen, Wuqiang Ma, Xinwen Hu, Kaibing Zhou

Subjects: Get full text

Polymorphisms of Codons 110, 146, 211 and 222 at the Goat <i>PRNP</i> Locus and Their Association with Scrapie in Greece by Athanasios I. Gelasakis, Evridiki Boukouvala, Maria Babetsa, Efstathios Katharopoulos, Vayia Palaska, Dimitra Papakostaki, Nektarios D. Giadinis, Dimitrios Loukovitis, Jan P. M. Langeveld, Loukia V. Ekateriniadou

“…Codon 110P was exclusively found in scrapie-negative brains, and homozygous 110P/P in two scrapie-negative goats. …”
Get full text

Why Were [GADV]-amino Acids and GNC Codons Selected and How Was GNC Primeval Genetic Code Established? by Kenji Ikehara

“…Correspondence relations between codons and amino acids are determined by genetic code. …”
Get full text

Analysis of the Codon Usage Pattern of HA and NA Genes of H7N9 Influenza A Virus by Jiumeng Sun, Wen Zhao, Ruyi Wang, Wenyan Zhang, Gairu Li, Meng Lu, Yuekun Shao, Yichen Yang, Ningning Wang, Qi Gao, Shuo Su

Subjects: Get full text

Evaluation and Determination of a Suitable Passage Number of Codon Pair Deoptimized PRRSV-1 Vaccine Candidate in Pigs by Min-A Lee, Su-Hwa You, Usharani Jayaramaiah, Eun-Gyeong Shin, Seung-Min Song, Lanjeong Ju, Seok-Jin Kang, Sun-Hee Cho, Bang-Hun Hyun, Hyang-Sim Lee

Subjects: Get full text

Generation of Premature Termination Codon (PTC)-Harboring Pseudorabies Virus (PRV) via Genetic Code Expansion Technology by Tong-Yun Wang, Guo-Ju Sang, Qian Wang, Chao-Liang Leng, Zhi-Jun Tian, Jin-Mei Peng, Shu-Jie Wang, Ming-Xia Sun, Fan-Dan Meng, Hao Zheng, Xue-Hui Cai, Yan-Dong Tang

Subjects: “…premature termination codon…”
Get full text