Showing 21 - 40 results of 5,147 for search '"codon"', query time: 0.12s Refine Results
  1. 21

    On ribosome load, codon bias and protein abundance. by Stefan Klumpp, Jiajia Dong, Terence Hwa

    Published 2012-01-01
    “…Different codons encoding the same amino acid are not used equally in protein-coding sequences. …”
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    Synonymous codon usage regulates translation initiation by Chloe L. Barrington, Gabriel Galindo, Amanda L. Koch, Emma R. Horton, Evan J. Morrison, Samantha Tisa, Timothy J. Stasevich, Olivia S. Rissland

    Published 2023-12-01
    “…Summary: Nonoptimal synonymous codons repress gene expression, but the underlying mechanisms are poorly understood. …”
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    Article
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    Evolutionary Dynamics of Abundant Stop Codon Readthrough by Fields, Gabriel, Lin, Michael F., Jungreis, Irwin, Chan, Clara S., Waterhouse, Robert, Kellis, Manolis

    Published 2017
    “…Using improved comparative genomics methods for detecting readthrough, we identify evolutionary signatures of conserved, functional readthrough of 353 stop codons in the malaria vector, Anopheles gambiae, and of 51 additional Drosophila melanogaster stop codons, including several cases of double and triple readthrough and of readthrough of two adjacent stop codons. …”
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    Codon Constraints on Closed 2D Shapes by Richards, Whitman, Hoffman, Donald D.

    Published 2004
    “…Codons are simple primitives for describing plane curves. …”
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    Forces acting on codon bias in malaria parasites by Sinha, I, Woodrow, C

    Published 2018
    “…Malaria parasite genomes have a range of codon biases, with Plasmodium falciparum one of the most AT-biased genomes known. …”
    Journal article
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    Genes Common in Primary Immunodeficiencies and Cancer Display Overrepresentation of Codon CTG and Dominant Role of Selection Pressure in Shaping Codon Usage by Rekha Khandia, Taha Alqahtani, Ali M. Alqahtani

    Published 2021-08-01
    “…The dinucleotide TpA adversely affected protein expression, while CpG did not. The CTG codon was the most overrepresented codon in 80.95% of genes. …”
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    Article
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    Codon-Precise, Synthetic, Antibody Fragment Libraries Built Using Automated Hexamer Codon Additions and Validated through Next Generation Sequencing by Laura Frigotto, Matthew E. Smith, Christopher Brankin, Ashni Sedani, Simon E. Cooper, Nisha Kanwar, Daniel Evans, Stanislava Svobodova, Claudia Baar, Jacob Glanville, Christopher G. Ullman, Anna V. Hine

    Published 2015-05-01
    “…We have previously described ProxiMAX, a technology that enables the fabrication of precise, combinatorial gene libraries via codon-by-codon saturation mutagenesis. ProxiMAX was originally performed using manual, enzymatic transfer of codons via blunt-end ligation. …”
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    Re-introducing non-optimal synonymous codons into codon-optimized constructs enhances soluble recovery of recombinant proteins from Escherichia coli. by Jennifer Konczal, Justin Bower, Christopher H Gray

    Published 2019-01-01
    “…This, in turn, has increased the application of codon-optimized cDNAs where codons rarely used by Escherchia coli are replaced with common synonymous codons to accelerate translation of the target. …”
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    Article
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