Improvement of Interferon-Beta Production in Transient Expression System of CHO DG44 by a Codon Bias Change in Instability Sequence (CRID) of C-terminal of Interferon Beta Gene by Zahra Bezi, Hassan Korbekandi, Batool Hashemibeni, Zohreh Hojjati, Amin Moradi Hassanabad, Mohammad Reza Marasi

“…The aim of this study was to investigate this effect by creating a codon bias change in instability sequence located in C-terminal of interferon beta protein (Coding region instability determinant or CRID). …”
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The p53 Codon 72 Pro/Pro Genotype Identifies Poor-Prognosis Neuroblastoma Patients: Correlation with Reduced Apoptosis and Enhanced Senescence by the p53-72P Isoform by Sara Cattelani, Giovanna Ferrari-Amorotti, Sara Galavotti, Raffaella Defferrari, Barbara Tanno, Samantha Cialfi, Jenny Vergalli, Valentina Fragliasso, Clara Guerzoni, Gloria Manzotti, Angela Rachele Soliera, Chiara Menin, Roberta Bertorelle, Heather P. McDowell, Alessandro Inserra, Maria Luisa Belli, Luigi Varesio, Deborah Tweddle, Gian Paolo Tonini, Pierluigi Altavista, Carlo Dominici, Giuseppe Raschellà, Bruno Calabretta

“…The p53 gene is rarely mutated in neuroblastoma, but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. …”
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Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure by Lindberg, MF, Le Gall, T, Carmoy, N, Berchel, M, Hyde, SC, Gill, D, Jaffrès, P, Lehn, P, Montier, T

Crystal structures of HIV-1 reverse transcriptase mutated at codons 100, 106 and 108 show nevirapine resistance is mediated via perturbation of interactions with Tyr181 or Tyr188 by Stammers, D, Ren, J, Nichols, C, Chamberlain, P, Weaver, K, Short, SA, Stuart, D

mRNA Analysis of Frameshift Mutations with Stop Codon in the Last Exon: The Case of Hemoglobins Campania [α1 cod95 (−C)] and Sciacca [α1 cod109 (−C)] by Giovanna Cardiero, Gennaro Musollino, Romeo Prezioso, Giuseppina Lacerra

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Identification of colorectal cancer patients with tumors carrying the <it>TP53 </it>mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy by Tsuchiya Eiju, Sakuma Yuji, Matsukuma Shoichi, Yoshihara Mitsuyo, Sekiyama Akiko, Sekiguchi Hironobu, Shiozawa Manabu, Tsuchida Kazuhito, Sugano Nobuhiro, Suda Tetsuji, Godai Ten-i, Kameda Yoichi, Akaike Makoto, Miyagi Yohei

“…In addition, the polymorphic status at p53 codon 72, which results in arginine or proline residues (R72P) and is thought to influence the function of the protein significantly, was not examined.…”
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747 CodaLytic™, a novel codon-pair deoptimized influenza virus creates an immune-stimulatory tumor microenvironment leading to monotherapy efficacy in a preclinical model of breast cancer by Steffen Mueller, Marcin Stawowczyk, Katie Pfeffer, Juliana Tafrova, Charles Stauft, Anna Kushnir, Sybil Tasker, J Robert Coleman, Johanna Kaufmann

Loss of a Premature Stop Codon in the Rice Wall-Associated Kinase 91 (<i>WAK91</i>) Gene Is a Candidate for Improving Leaf Sheath Blight Disease Resistance by Noor Al-Bader, Austin Meier, Matthew Geniza, Yamid Sanabria Gongora, James Oard, Pankaj Jaiswal

“…The consequence of the resistant allele C is a stop codon loss, resulting in an open reading frame with extra 62 amino acid carrying a longer protein kinase domain and additional phosphorylation sites. …”
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Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects. by Hannan, F, Howles, S, Rogers, A, Cranston, T, Gorvin, C, Babinsky, V, Reed, A, Thakker, C, Bockenhauer, D, Brown, R, Connell, J, Cook, J, Darzy, K, Ehtisham, S, Graham, U, Hulse, T, Hunter, S, Izatt, L, Kumar, D, McKenna, M, McKnight, J, Morrison, P, Mughal, M, O'Halloran, D, Pearce, S, Porteous, M, Rahman, M, Richardson, T, Robinson, R, Scheers, I, Siddique, H, Van't Hoff, W, Wang, T, Whyte, M, Nesbit, M, Thakker, R

Augmenting tomato functional genomics with a genome-wide induced genetic variation resource by Prateek Gupta, Prateek Gupta, Pankaj Singh Dholaniya, Kunnappady Princy, Athira Sethu Madhavan, Yellamaraju Sreelakshmi, Rameshwar Sharma

Subjects: “…codon usage…”
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Variation of natural selection in the Amoebozoa reveals heterogeneity across the phylogeny and adaptive evolution in diverse lineages by Fang Wang, Yonas I. Tekle

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Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population by M.A.C. Smith, M.D.A. Silva, L.Q. Araujo, L.R. Ramos, R.W. Labio, R.R. Burbano, C.A. Peres, S.B. Andreoli, S.L.M. Payão, M.S. Cendoroglo

Subjects: “…WRN: codon 1367 polymorphism…”
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A novel frameshift mutation in DNAH6 associated with male infertility and asthenoteratozoospermia by Fei Huang, Jun Zeng, Dan Liu, Jing Zhang, Boluo Liang, Jingping Gao, Rong Yan, Xiaobo Shi, Jianlin Chen, Wanjuan Song, Hua-Lin Huang

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De novo assembly and comparative analysis of the mitochondrial genome of Reynoutria japonica by Jianhui Chen, Hongping Ma, Haili Fan, Fan Lin, Tuanyao Chai, Hong Wang

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Plastid Phylogenomics of <i>Paeonia</i> and the Evolution of Ten Flower Types in Tree Peony by Wen Li, Xin-Cheng Huang, Yi-Lei Wang, Rui-Ju Zhang, Dong-Yan Shi, Teng-Fei Li, Guang-Can Zhou, Jia-Yu Xue

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Quantitative analysis of mammalian translation initiation sites by FACS‐seq by William L Noderer, Ross J Flockhart, Aparna Bhaduri, Alexander J Diaz de Arce, Jiajing Zhang, Paul A Khavari, Clifford L Wang

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The complete chloroplast genome of Dendrobium nobile, an endangered medicinal orchid from north-east India and its comparison with related Dendrobium species by Ruchishree Konhar, Manish Debnath, Santosh Vishwakarma, Atanu Bhattacharjee, Durai Sundar, Pramod Tandon, Debasis Dash, Devendra Kumar Biswal

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Design of the env-su Gene Coding for Surface Unit Protein as a Vaccine Candidate for Jembrana Disease Virus in In Silico by Nur Asih Setiarini, Indriawati Indriawati, R Susanti Susanti, Endang Tri Margawati

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Functional Restoration of BRCA1 Nonsense Mutations by Aminoglycoside-Induced Readthrough by Renata B. V. Abreu, Thiago T. Gomes, Thales C. Nepomuceno, Thales C. Nepomuceno, Xueli Li, Mateus Fuchshuber-Moraes, Giuliana De Gregoriis, Guilherme Suarez-Kurtz, Alvaro N. A. Monteiro, Marcelo A. Carvalho, Marcelo A. Carvalho

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In Silico Analyses of Autophagy-Related Genes in Rapeseed (<i>Brassica napus</i> L.) under Different Abiotic Stresses and in Various Tissues by Elham Mehri Eshkiki, Zahra Hajiahmadi, Amin Abedi, Mojtaba Kordrostami, Cédric Jacquard

Subjects: “…codon usage bias…”
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