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1741
The complete mitochondrial genome of Archamia macropterus (Perciformes; Apogonidae) and phylogenetic studies of Perciformes
Published 2019-07-01“…All protein-coding genes started with an ATG initiation codon, except COI used GTG. With the exception of ND6, all other genes were encoded on the heavy strand, the NJ tree demonstrated that A. macropterus has a closest relationship with Cheilodipterus quinquelineatus and Apogon semilineatus.…”
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1742
Mitochondrial genome of Bolanusoides shaanxiensis (Cicadellidae: Typhlocybinae: Typhlocybini), with its phylogenetic analysis
Published 2020-01-01“…Most of PCGs started with ATN and stopped with TAA, except for ATP8 started with TTG, COX2, COX3 and ND5 used incomplete T as stop codon. The phylogeny tree is monophyletic among 31 related species. …”
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1743
Genetic Code Engineering by Natural and Unnatural Base Pair Systems for the Site-Specific Incorporation of Non-Standard Amino Acids Into Proteins
Published 2022-05-01“…If we expand the genetic code or develop alternative codes, we could create novel biological systems and biotechnologies by the site-specific incorporation of non-standard amino acids (or unnatural amino acids, unAAs) into proteins. To this end, new codons and their complementary anticodons are required for unAAs. …”
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1744
Base molecular de uma beta-talassémia de transmissão dominante.
Published 1999-11-01“…The G-->T transversion at codon 121 of the beta-globin gene was found in the affected individuals in association with Orkin's haplotype V. …”
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1745
The complete mitochondrial genome of the Adonis ladybird, Hippodamia variegata (Coleoptera: Coccinellidae)
Published 2019-01-01“…The mitogenome is 17,823 bp in length, consisting of 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two ribosomal RNA (rRNA) genes, and one non-coding control region. Initiation codons ATA, ATG, ATT, and AAT were identified in two, five, five, and one PCGs, respectively, whereas stop codons TAA or TAG were found in eight genes except for five genes which use incomplete stop codon T–. …”
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1746
The complete mitochondrial genome of the parasitic sheep ked Melophagus ovinus (Diptera: Hippoboscidae)
Published 2017-12-01“…Its organization and characteristics, including the size, structure, gene order, start/stop codon usage and gene overlaps, are largely typical for Diptera. …”
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1747
Characterization of the complete mitochondrial genome of Tripetaloceroides tonkinensis (Orthoptera: Tetrigoidea) from China and its phylogenetic analysis
Published 2021-07-01“…Thirteen PCGs started with typical ATN codon and ended with complete stop codons (five with TAG, eight with TAA). …”
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1748
The complete mitochondrial genome of Tenomerga trabecula (Coleoptera: Archostemata: Cupedidae) and phylogenetic analysis among Coleoptera
Published 2022-02-01“…The genome organization, nucleotide composition, and codon usage are similar to other beetles. Phylogenetic analysis shows that Archostemata is monophyletic. …”
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1749
Phylogenetic analysis of the complete mitochondrial genome of the graphic beauty butterfly Baeotus beotus (Doubleday 1849) (Lepidoptera: Nymphalidae: Nymphalinae: Coeini)
Published 2021-04-01“…Baeotus beotus COX1 features an atypical CGA start codon and COX1, COX2, ND1, and ND4 exhibit incomplete stop codons completed by the addition of 3’ A residues to the mRNA. …”
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1750
Isolation of a cDNA encoding an IgG immunoreactive antigen (zinc finger protein) of Strongyloides stercoralis
Published 2001-06-01“…The nucleotide sequence of the 1,328 bp insert was found to be 70.5% ; A/T, reflecting a characteristic A/T codon bias of S. stercoralis. The nucleotide sequence of this insert identified a cDNA coding for a zinc finger protein. …”
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1751
Clustering-Based Methods for Clinical Risk Prediction of Rare Missense Variants
Published 2022“…Typically, variants which lead to loss of function (e.g. nonsense or stop-codon inducing variants, frameshifts, or deletions) are more easily classified as pathogenic in an established disease gene. …”
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1752
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis.
Published 2003“…A polymorphism encoding either arginine (72R) or proline (72P) at codon 72 of p53 influences inhibition of p73 by a range of p53 mutants identified in squamous cancers. …”
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1753
Characterisation of the membrane-extrinsic domain of the TatB component of the twin arginine protein translocase.
Published 2011“…We were unable to isolate transport-inactive single codon substitution mutations in tatB suggesting that the precise amino acid sequence of TatB is not critical to its function.…”
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1754
Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam.
Published 2005“…A polymorphism in the TLR5 gene introduces a premature stop codon (TLR5(392STOP)) that is associated with susceptibility to legionnaires disease. …”
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1755
Mutant prolactin receptor and familial hyperprolactinemia
Published 2013“…These symptoms were not associated with pituitary tumors or multiple endocrine neoplasia but were due to a heterozygous mutation in the prolactin receptor gene, PRLR, resulting in an amino acid change from histidine to arginine at codon 188 (His188Arg). This substitution disrupted the high-affinity ligand-binding interface of the prolactin receptor, resulting in a loss of downstream signaling by Janus kinase 2 (JAK2) and signal transducer and activator of transcription 5 (STAT5). …”
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1756
Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa.
Published 2003“…The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in Plasmodium falciparum is associated with high sulfadoxine /pyrimethamine (SP) resistance. …”
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1757
Allelic variation of the 5-HT2C receptor (HTR2C) in bulimia nervosa and binge eating disorder.
Published 1999“…There is a common polymorphism of the human 5-HT2C receptor at codon 23 (cys23ser) which has been reported to be a risk factor for certain psychiatric disorders and a predictor of their pharmacotherapeutic response. …”
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1758
Heterosexual transmission of human immunodeficiency virus type 1 variants associated with zidovudine resistance.
Published 1994“…DNA sequencing of HIV-1 proviruses confirmed that these 2 persons shared HIV genetic variants, including a mutation at codon 70 in the reverse transcriptase gene associated with reduced in vitro sensitivity to zidovudine. …”
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1759
From chemical mutagenesis to post-expression mutagenesis: A 50 year odyssey.
Published 2016“…The ongoing maturation of stop codon suppression and related technologies for unnatural amino acid incorporation has greatly expanded access to nonstandard amino acids by expanding the scope of the translational apparatus. …”
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1760
Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia.
Published 2009“…Two human-specific polymorphisms, p53 codon 72 and MDM2 SNP309, influence the activities of p53. …”
Journal article