Effects of different concentrations of pineapple core extract and maceration process on free-range chicken meat quality by Hussain, Norhayati, Choy, Hew Weng, Munawar, Nursabrina

New mutation of the TP53 gene associated with the hereditary breast cancer in a young Tuvinian woman by P. A. Gervas, A. Yu. Molokov, A. A. Zarubin, A. A. Ponomareva, N. N. Babyshkina, V. A. Belyavskaya, L. F. Pisareva, E. L. Choynzonov, N. V. Cherdyntseva

“…In accordance with proteinpaint tool, the lrg_321t1: c.80c>t mutation is located in functionally specialized transactivation domains and codon of the tp53 gene, where the pathogenic mutation associated with li-Fraumeni syndrome has been earlier described. …”
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Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events by George Allen, Benjamin Weiss, Olesya O. Panasenko, Susanne Huch, Zoltan Villanyi, Benjamin Albert, Daniel Dilg, Marina Zagatti, Paul Schaughency, Susan E. Liao, Jeff Corden, Christine Polte, David Shore, Zoya Ignatova, Vicent Pelechano, Martine A. Collart

“…We show that depletion of Not1 and Not4 inversely impacts mRNA solubilities and, for soluble mRNAs, ribosome dwelling according to codon optimality. Depletion of Not4 solubilizes mRNAs with lower non-optimal codon content and higher expression that are rendered insoluble by Not1 depletion. …”
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Decoding the complete organelle genomic architecture of Stewartia gemmata: an early-diverging species in Theaceae by Daliang Liu, Zhihan Zhang, Yanlin Hao, Mengge Li, Houlin Yu, Xingruo Zhang, Haoyang Mi, Lin Cheng, Yiyong Zhao

“…In organelle genomes, the protein-coding genes exhibited a strong A/U bias at codon endings; ENC-GC3 analysis implies selection-driven codon bias. …”
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Complete mitochondrial genome of the endangered Prunus pedunculata (Prunoideae, Rosaceae) in China: characterization and phylogenetic analysis by Qian Liu, Zinian Wu, Zinian Wu, Chunyu Tian, Yanting Yang, Lemeng Liu, Yumei Feng, Zhiyong Li, Zhiyong Li

“…The most frequently used codon was UUU (Phe), with a relative synonymous codon usage (RSCU) value of 1.12. …”
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On origin of genetic code and tRNA before translation by Szathmáry Eörs, Rodin Andrei S, Rodin Sergei N

“…Formally, the concomitant presence of codons and anticodons is also expected in the reverse situation, with codons containing palindrome-dinucleotides at their 2-3 positions, and anticodons exhibiting them at 1-2 positions. …”
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Characterization of <i>Angraecum</i> (Angraecinae, Orchidaceae) Plastomes and Utility of Sequence Variability Hotspots by Cheng-Yuan Zhou, Wen-Jun Lin, Ruyi Li, Yuhan Wu, Zhong-Jian Liu, Ming-He Li

“…A total of 30 to 46 long repeats and 55 to 63 SSRs were identified. Relative synonymous codon usage (RSCU) analysis indicated a high degree of conservation in codon usage bias. …”
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A systematic optimization of styrene biosynthesis in Escherichia coli BL21(DE3) by Changqing Liu, Xiao Men, Hailin Chen, Meijie Li, Zhaorui Ding, Guoqiang Chen, Fan Wang, Haobao Liu, Qian Wang, Youshuang Zhu, Haibo Zhang, Mo Xian

“…Systematic optimization of styrene biosynthesis, such as enzyme screening, codon and plasmid optimization, metabolic flow balance, and in situ fermentation was performed. …”
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Genome-Wide Identification and Characterization of <i>DnaJ</i> Gene Family in Grape (<i>Vitis vinifera</i> L.) by Tianchi Chen, Tao Xu, Tianye Zhang, Tingting Liu, Leyi Shen, Zhihui Chen, Yueyan Wu, Jian Yang

“…Gene duplication analysis demonstrated that segmental and tandem duplication may not be the dominant pathway of gene expansion in the <i>VvDnaJ</i> gene family. Codon usage pattern analysis showed that the codon usage pattern of <i>VvDnaJs</i> differs obviously from the monocotyledon counterparts. …”
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Rapid Screening and Comparison of Chimeric Lysins for Antibacterial Activity against <i>Staphylococcus aureus</i> Strains by Jin-Mi Park, Dae-Sung Ko, Hee-Soo Kim, Nam-Hyung Kim, Eun-Kyoung Kim, Young-Hye Roh, Danil Kim, Jae-Hong Kim, Kang-Seuk Choi, Hyuk-Joon Kwon

“…ALS2 expressed in <i>E. coli</i> showed two major bands, and the smaller one (subprotein) was shown to be expressed by an innate downstream promoter and start codon (ATG). The introduction of synonymous mutations in the promoter resulted in clearly reduced expression of the subprotein, whereas missense mutations in the start codon abolished antibacterial activity as well as subprotein production. …”
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Analysis of cell-free DNA concentration, fragmentation patterns and TP53 gene expression in mammary tumor-bearing dogs: A pilot study by Silvia Guil-Luna, Silvia Guil-Luna, Silvia Guil-Luna, Raquel Sánchez-Céspedes, Aurora Rivas Crespo, María Dolores Fernández, José Andrés Fernández Sarmiento, Antonio Rodríguez-Ariza, Antonio Rodríguez-Ariza, Yolanda Millán

“…In addition, although no detection of the point mutation in codon 245 of TP53 gene could be detected neither in plasma nor tumor tissue, an increased TP53 expression was detected in animals with tumors bearing malignant characteristics. …”
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Profiling of Transcriptome-Wide N6-Methyladenosine (m6A) Modifications and Identifying m6A Associated Regulation in Sperm Tail Formation in <i>Anopheles sinensis</i> by Congshan Liu, Jianping Cao, Haobing Zhang, Jiatong Wu, Jianhai Yin

“…Distinct from mammals and yeast but similar to <i>Arabidopsis thaliana</i>, m6A in <i>An. sinensis</i> is enriched not only around the stop codon and within 3′-untranslated regions but also around the start codon and 5′-UTR. …”
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Enhanced Biosynthesis of 2-Deoxy-scyllo-inosose in Metabolically Engineered Bacillus subtilis Recombinants by Joo Hyun Lim, Hyun Ha Hwang, Na Joon Lee, Jae Woo Lee, Eun Gyo Seo, Hye Bin Son, Hye Ji Kim, Yeo Joon Yoon, Je Won Park, Je Won Park

“…After that, three different DOI synthase–encoding genes, which were artificially synthesized according to the codon preference of the B. subtilis host, were separately introduced into the engineered recombinants. …”
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<i>YPK9</i> and <i>WHI2</i> Negatively Interact during Oxidative Stress by Florenal Joseph, Darach Miller, Oleg V. Evgrafov, William J. Chirico

“…Together, these results demonstrate a novel premature stop codon in <i>WHI2</i> that renders yeast sensitive to hydrogen peroxide; they also reveal a negative genetic interaction between <i>WHI2</i> and <i>YPK9</i> in the presence of hydrogen peroxide in the BY4741 background.…”
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<i>yaaJ</i>, the tRNA-Specific Adenosine Deaminase, Is Dispensable in <i>Bacillus subtilis</i> by Akiko Soma, Atsushi Kubota, Daisuke Tomoe, Yoshiho Ikeuchi, Fujio Kawamura, Hijiri Arimoto, Yuh Shiwa, Yu Kanesaki, Hideaki Nanamiya, Hirofumi Yoshikawa, Tsutomu Suzuki, Yasuhiko Sekine

“…A β−galactosidase reporter assay revealed that the translational activity of CGN codons was not impaired in the <i>yaaJ</i>-deletion mutant. …”
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Werewolf, There Wolf: Variants in <i>Hairless</i> Associated with Hypotrichia and Roaning in the Lykoi Cat Breed by Reuben M. Buckley, Barbara Gandolfi, Erica K. Creighton, Connor A. Pyne, Delia M. Bouhan, Michelle L. LeRoy, David A. Senter, Johnny R. Gobble, Marie Abitbol, Leslie A. Lyons, 99 Lives Consortium

“…The lykoi cat was a compound heterozygote for two loss of function variants in <i>HR</i>, an exon 3 c.1255_1256dupGT (chrB1:36040783), which should produce a stop codon at amino acid 420 (p.Gln420Serfs*100) and, an exon 18 c.3389insGACA (chrB1:36051555), which should produce a stop codon at amino acid position 1130 (p.Ser1130Argfs*29). …”
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Investigation of Isocitrate Dehydrogenase 1 and 2 Mutations in Acute Leukemia Patients in Saudi Arabia by Heba Alkhatabi, Haneen Abdulfattah Bin Saddeq, Luay Alyamani, Thoraia Shinawi, Elrashed B. Yasin, Raed Alserihi, Raed Felimban, Hossam H. Tayeb, Rawan Mimani, Zainab Alalla, Muhammad Abu-Elmagd, Adel Abuzenadah

“…Mutations in IDH1 were detected in 7 out of 43 (16.2%) AML patients; 5 of them occurred at codon R132. The other two mutations included a single-nucleotide polymorphism, which affected codon G105 in one patient. …”
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Mitogenomic Characterization and Phylogenetic Placement of African Hind, <i>Cephalopholis taeniops</i>: Shedding Light on the Evolution of Groupers (Serranidae: Epinephelinae) by Shantanu Kundu, Hye-Eun Kang, Ah Ran Kim, Soo Rin Lee, Eun-Bi Kim, Muhammad Hilman Fu’adil Amin, Sapto Andriyono, Hyun-Woo Kim, Kyoungmi Kang

“…The relative synonymous codon usage analysis revealed the maximum abundance of leucine, proline, serine, and threonine. …”
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Structural Features and Phylogenetic Implications of Crinoid Echinoderms Based on Thirteen Novel Mitochondrial Genomes by Qinzeng Xu, Min Lu, Yuyao Sun, Zhong Li, Yixuan Li, Yue Dong, Xuying Hu, Qian Zhang, Bing Liu, Xuebao He

“…Additionally, our analysis of protein-coding genes highlights a preference for A + T nucleotides, along with specific start and stop codon usage, offering insights into codon bias and its implications for protein synthesis and function. …”
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Isopropanol production with engineered Cupriavidus necator as bioproduction platform by Grousseau, Estelle, Lu, Jingnan, Gorret, Nathalie, Guillouet, Stéphane E., Sinskey, Anthony J

“…These synthetic production pathways were rationally designed through codon optimization, gene placement, and gene dosage in order to efficiently divert carbon flow from P(3HB) precursors toward isopropanol. …”
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