Showing 161 - 180 results of 5,147 for search '"codon"', query time: 0.11s Refine Results
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    tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum by Dedon, Peter C., Preiser, Peter Rainer, Ng, Chee Sheng, Sinha, Ameya, Aniweh, Yaw, Nah, Qianhui, Babu, Indrakanti Ramesh, Gu, Chen, Chionh, Yok Hian

    Published 2019
    “…Quantitative analysis of ~2,100 proteins across the IDC revealed that up‐ and down‐regulated proteins in late but not early stages have a marked codon bias that directly correlates with parallel changes in tRNA modifications and enhanced translational efficiency. …”
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    Journal Article
  4. 164

    Inter-oligomer interactions of the human prion protein are modulated by the polymorphism at codon 129. by Gerber, R, Voitchovsky, K, Mitchel, C, Tahiri-Alaoui, A, Ryan, J, Hore, P, James, W

    Published 2008
    “…The common polymorphism at codon 129 in the human prion protein (PrP) has been shown in many studies to influence not only the pathology of prion disease but also the misfolding propensity of PrP. …”
    Journal article
  5. 165

    RNA codons govern the mechanism of protein folding through the shape memory effect by Hou, Pin Yoong

    Published 2022
    “…Specifically, can RNA codons define the protein folding mechanism? This review will first present existing mechanisms for protein folding and their limitations. …”
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    Article
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    Freqüência de mutação no códon 12 do gene K-ras no carcinoma ductal invasivo de mama Frequency of mutations at codon 12 of the K--ras gene in invasive ductal breast cancer by Sônia Maria Rolim Rosa Lima, Sebastião Piato, Roberto Euzébio dos Santos, Euclides Matheucci Junior, Osmar Monte

    Published 1999-04-01
    “…Objetivo: pesquisar a freqüência de mutação pontual no códon 12 do gene K-ras, em espécimes cirúrgicos de pacientes portadoras de carcinoma ductal invasivo de mama. …”
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    Article
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    Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon by David Teran, Ying Zhang, Andrei A. Korostelev

    Published 2024-03-01
    “…As tmRNA presents the first alanine codon via a non-canonical mRNA path in the ribosome, the incoming alanyl-tRNA must rearrange the tmRNA molecule to read the codon. …”
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    Article
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    2348 Lafora disease premature termination codons (PTCs) are likely candidates for suppression by aminoglycosides by Zoe R. Simmons, Amanda Sherwood, Selena Li, Sylvie Garneau-Tsodikova, Matthew Gentry

    Published 2018-06-01
    “…For 10% of patients with a genetic disease, a nonsense/STOP mutation/premature termination codon (PTC) is the underlying cause of their malady. …”
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    Article
  15. 175

    Exploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo. by Jessica K Sawyer, Zahra Kabiri, Ruth A Montague, Scott R Allen, Rebeccah Stewart, Sarah V Paramore, Erez Cohen, Hamed Zaribafzadeh, Christopher M Counter, Donald T Fox

    Published 2020-12-01
    “…In multiple contexts, we show that RpS21 preferentially influences weak Ras/MAPK signaling outputs. These data show that codon usage manipulation can identify new, output-specific signaling regulators, and identify RpS21 as an in vivo Ras/MAPK phenotypic regulator.…”
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    Article
  16. 176

    Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue by Natalie Jing Ma, Colin F Hemez, Karl W Barber, Jesse Rinehart, Farren J Isaacs

    Published 2018-10-01
    “…Organisms possessing genetic codes with unassigned codons raise the question of how cellular machinery resolves such codons and how this could impact horizontal gene transfer. …”
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    Article
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    Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD by Tanzeen Yusuff, Tanzeen Yusuff, Ya-Chu Chang, Ya-Chu Chang, Tzu-Kang Sang, Tzu-Kang Sang, George R. Jackson, George R. Jackson, George R. Jackson, George R. Jackson, George R. Jackson, Shreyasi Chatterjee, Shreyasi Chatterjee, Shreyasi Chatterjee

    Published 2023-03-01
    “…In a novel Drosophila melanogaster model, we report gain-of-function phenotypes due to misexpression of insect codon-optimized version of human wild-type TDP-43 (CO-TDP-43) using both the binary GAL4/UAS system and direct promoter fusion constructs. …”
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    Article
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