Showing 1 - 20 results of 5,147 for search '"codon"', query time: 0.13s Refine Results
  1. 1

    Relative synonymous codon usage and codon pair analysis of depression associated genes by Rekha Khandia, Pankaj Gurjar, Mohammad Amjad Kamal, Nigel H. Greig

    Published 2024-02-01
    “…Information based on codon usage, preferred codons, rare, and codon context might be used in constructing a deliverable synthetic construct to correct the gene expression level of the human body, which is altered in the depressive state. …”
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    Extended stop codon context predicts nonsense codon readthrough efficiency in human cells by Kotchaphorn Mangkalaphiban, Lianwu Fu, Ming Du, Kari Thrasher, Kim M. Keeling, David M. Bedwell, Allan Jacobson

    Published 2024-03-01
    “…Abstract Protein synthesis terminates when a stop codon enters the ribosome’s A-site. Although termination is efficient, stop codon readthrough can occur when a near-cognate tRNA outcompetes release factors during decoding. …”
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    Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli by Napolitano, Michael G., Landon, Matthieu, Gregg, Christopher J., Lajoie, Marc J., Govindarajan, Lakshmi, Mosberg, Joshua A., Kuznetsov, Gleb, Vargas-Rodriguez, Oscar, Isaacs, Farren J., Söll, Dieter, Goodman, Daniel Bryan, Church, George M

    Published 2017
    “…The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and translational properties distinct from the other synonymous alternatives (CGN). …”
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    Codon Usage Bias in Phytoplankton by Marc Krasovec, Dmitry A. Filatov

    Published 2022-01-01
    Subjects: “…codon usage bias…”
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    The imprint of codons on protein structure. by Deane, C, Saunders, R

    Published 2011
    “…Here, past and present research regarding synonymous codons and codon translation speed are reviewed within the context of protein structure attainment.…”
    Journal article
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    Codon usage bias in phytoplankton by Krasovec, M, Filatov, DA

    Published 2022
    “…Non-random usage of synonymous codons, known as “codon bias”, has been described in many organisms, from bacteria to Drosophila, but little is known about it in phytoplankton. …”
    Journal article
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    Codon-specific Ramachandran plots show amino acid backbone conformation depends on identity of the translated codon by Aviv A. Rosenberg, Ailie Marx, Alex M. Bronstein

    Published 2022-05-01
    “…This study uncovers a dependence between local amino acid conformation in folded proteins and the identity of the codon from which that amino acid was translated.…”
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  9. 9

    Stop codons in bacteria are not selectively equivalent by Povolotskaya Inna S, Kondrashov Fyodor A, Ledda Alice, Vlasov Peter K

    Published 2012-09-01
    “…<p>Abstract</p> <p>Background</p> <p>The evolution and genomic stop codon frequencies have not been rigorously studied with the exception of coding of non-canonical amino acids. …”
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  10. 10

    Genome landscapes and bacteriophage codon usage. by Julius B Lucks, David R Nelson, Grzegorz R Kudla, Joshua B Plotkin

    Published 2008-02-01
    “…Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonymous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of codon usage in prokaryotes and simple eukaryotes. …”
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    Evolution of codon usage bias in diatoms by Krasovec, M, Filatov, D

    Published 2019
    “…Codon usage bias (CUB)—preferential use of one of the synonymous codons, has been described in a wide range of organisms from bacteria to mammals, but it has not yet been studied in marine phytoplankton. …”
    Journal article
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    Heterogeneity in codon usages of sobemovirus genes. by Zhou, H, Wang, H, Huang, L, Naylor, M, Clifford, P

    Published 2005
    “…Most interestingly, the codon usages of the viral ORF-2 that encodes the replicase showed affinity to that of the plants whereas codon usages of the other viral ORFs were not relevant to the host species. …”
    Journal article
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    Amino acid repeats avert mRNA folding through conservative substitutions and synonymous codons, regardless of codon bias by Sailen Barik

    Published 2017-12-01
    “…A close examination of their codon pattern and analysis of RNA structure propensity led to the following set of empirical rules: (1) One class of amino acid repeats (Class I) uses a mixture of synonymous codons, some of which approximate the codon bias ratio in the overall human proteome; (2) The second class (Class II) disregards the codon bias ratio, and appears to have originated by simple repetition of the same codon (or just a few codons); and finally, (3) In all AARs (including Class I, Class II, and the in-betweens), the codons are chosen in a manner that precludes the formation of RNA secondary structure. …”
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    Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization tool by Doyle, Francis, Leonardi, Andrea, Endres, Lauren, Tenenbaum, Scott A., Begley, Thomas J., Dedon, Peter C

    Published 2018
    “…There are 64 possible codons in the genetic code, with codons for the ∼20 amino acids and 3 stop codons having 1- to 6-fold degeneracy. …”
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