Improving Accessibility in the Emergency Department for Patients with Disabilities: A Qualitative Study by J. Harrison Carmichael, Kelly M. Kalagher, Martin A Reznek, Payal Modi

“…Methods: Twelve individuals with either physical or cognitive disabilities, visual impairments or blindness were interviewed regarding their ED experiences, particularly related to accessibility. …”
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Erigeron breviscapus (Vant.) Hand-Mazz.: A Promising Natural Neuroprotective Agent for Alzheimer’s Disease by Xiaoyu Dong, Shengtao Qu

“…Studies have shown that EBHM and its active ingredients have a variety of pharmacological effects with good therapeutic effects and wide application prospects for cognitive disability-related diseases. However, to our best knowledge, only few review articles have been published on the anti-AD effects of EBHM. …”
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Case of Acute Disseminated Encephalomyelitis Associated with Cytomegalovirus Reactivation in an Immunocompromised Systemic Lupus Erythematosus Patient by Mirela Pavicic Ivelja, Kresimir Dolic, Daniela Marasovic Krstulovic, Gordana Glavina, Ivo Ivic

“…We present a case of an immunocompromised systemic lupus erythematosus female patient admitted to our hospital for general impairment, monoparesis, and temporary cognitive disability. The case represented a significant diagnostic and therapeutic challenge primarily because of a wide range of differential diagnosis options (CNS lupus, ischemic cerebrovascular disease, viral meningoencephalitis, progressive multifocal leukoencephalopathy, limbic encephalitis, and acute disseminated encephalomyelitis—ADEM). …”
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Nanotechnology-Based Drug Delivery Strategies to Repair the Mitochondrial Function in Neuroinflammatory and Neurodegenerative Diseases by Luis F. González, Lorenzo E. Bevilacqua, Rodrigo Naves

“…In addition, we review different strategies for selective mitochondria-specific ligand targeting and discuss novel nanomaterials, nanozymes, and drug-loaded nanosystems developed to repair mitochondrial function and their therapeutic benefits protecting against oxidative stress, restoring cell energy production, preventing cell death, inhibiting protein aggregates, and improving motor and cognitive disability in cellular and animal models of different NI&NDDs.…”
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Habits and oral hygiene status of indigenous people with disabilities from the Misak community, Colombia by Herney Alonso Rengifo-Reina, Cinthya Solórzano-Vera, Ángela Liliana Grandas-Ramírez

“…Of these, 45.7% were women and aged 22.6 years in average. Cognitive disability was the most common, (54.3%). The study showed that 43.4% of people with disabilities brush their teeth at least once a day, with 44% needing help to do so. …”
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Trunk and craniofacial asymmetry are not associated in the general population: a cross-sectional study of 1029 adolescents by Chiara Arienti, Jorge Hugo Villafañe, Sabrina Donzelli, Fabio Zaina, Riccardo Buraschi, Stefano Negrini

“…Exclusion criteria were subjects with physical and cognitive disability, genetic disease, and polymorphism. …”
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Digital technologies for promoting the inclusion of workers with disabilities: A brief investigation by Varriale Luisa, Briganti Paola, Volpe Tiziana, Minucci Giovanni

“…This paper investigates the role and function of digital technologies within firms, widely believed to make them much more sustainable and promote the social inclusion of people with disability (PWD) at the workplace, especially those with cognitive disability or autism spectrum disorder (ASD). In the last thirty years, and more recently due to the COVID-19 pandemic, technological change related to digital transformation, hence the adoption and diffusion of digital technologies, has impacted every field and sector in private and professional life, both positively and negatively. …”
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Siblings’ Influence on the Motor Competence of Preschoolers by Luis P. Rodrigues, Carlos Luz, Rita Cordovil, Rui Mendes, Rita Alexandre, Vítor P. Lopes

“…One hundred and sixty-one children (87 boys, 74 girls) from 3.0 to 6.0 years of age (34 only children, 125 siblings) and with no known motor or cognitive disability were assessed using the Motor Competence Assessment (MCA). …”
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Evaluating Quality of Life of Parents Having a Child with Disability by Rita Kumari Ban, Iswari Luitel, Kalpana Regmi

“…There is a moderate positive correlation between psychosocial and the social domains. Cognitive disability mean score was highest on social domain that is 14.91and lowest on the physical domain (13.87). …”
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Alteration of brain nuclei in obese children with and without Prader-Willi syndrome by Ning Wu, Huan Yu, Mingze Xu

“…Twelve age- and sex-matched children with PWS, 18 obese children without PWS (OB) and 18 healthy controls participated in this study.Results: Compared with control and OB individuals, the PWS group exhibited significant atrophy in the bilateral thalamus, pallidum, hippocampus, amygdala, nucleus accumbens, right caudate, bilateral hypothalamus (left anterior-inferior, bilateral posterior, and bilateral tubular inferior subunits) and bilateral DCN (dentate, interposed, and fastigial nuclei), whereas no significant difference was found between the OB and control groups.Discussion: Based on our evidence, we suggested that alterations in brain nuclei influenced by imprinted genes were associated with clinical manifestations of PWS, such as eating disorders, cognitive disability and endocrine abnormalities, which were distinct from the neural mechanisms of obese children.…”
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Regulatory functions and pathological relevance of the MECP2 3′UTR in the central nervous system by Heather McGowan, Zhiping P. Pang

“…Loss-of-function mutations in MECP2 cause Rett syndrome (RTT), a debilitating neurodevelopmental disorder characterized by a phase of normal development, followed by the progressive loss of milestones and cognitive disability. While a great deal has been discovered about the structure, function, and regulation of MeCP2 in the time since its discovery as the genetic cause of RTT, including its involvement in a number of RTT-related syndromes that have come to be known as MeCP2-spectrum disorders, much about this multifunctional protein remains enigmatic. …”
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Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study by Ihab Hajjar, Salim S. Hayek, Felicia C. Goldstein, Greg Martin, Dean P. Jones, Arshed Quyyumi

“…The objective of this study is to investigate the association between aminothiol markers of OS and inflammation in cognitive decline, especially in the executive cognitive domain which is highly susceptible to cardiovascular risk factors and is an important predictor of cognitive disability. Methods The study design is that of a longitudinal cohort study within the setting of a large academic institution with participants being university employees (n = 511), mean age 49 years, 68% women, and 23% African-American. …”
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Remyelination alters the pattern of myelin in the cerebral cortex by Jennifer Orthmann-Murphy, Cody L Call, Gian C Molina-Castro, Yu Chen Hsieh, Matthew N Rasband, Peter A Calabresi, Dwight E Bergles

“…Destruction of oligodendrocytes and myelin sheaths in cortical gray matter profoundly alters neural activity and is associated with cognitive disability in multiple sclerosis (MS). Myelin can be restored by regenerating oligodendrocytes from resident progenitors; however, it is not known whether regeneration restores the complex myelination patterns in cortical circuits. …”
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Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury by Chrzaszcz MaryAnn, Venkatesan Charu, Choi Nicole, Wainwright Mark S

“…Magnetic resonance imaging scans now allow early detection of axonal injury following TBI, and have linked cognitive disability in these patients to white matter signal changes. …”
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The stress-related changes in the cerebral blood flow in newborn rats with intracranial hemorrhage: metabolic and endothelial mechanisms by Olga Sindeeva, Ekaterina Borisova, Arkady Abdurashitov, Ekaterina Zhinchenko, Artem Gekalyuk, Maria Ulanova, Aly Esmat Sharif, Victoria Razubaeva, Sergey Serov, Ludmila Yankovskaya, Valery V. Tuchin, Oxana Semyachkina-Glushkovskaya

“…Neonatal brain hemorrhages is a major problem of future generation’s health due to the high rate of cognitive disability of newborns after vascular catastrophes in the brain. …”
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Rare predicted loss of function alleles in Bassoon (BSN) are associated with obesity by Na Zhu, Charles A. LeDuc, Ilene Fennoy, Blandine Laferrère, Claudia A. Doege, Yufeng Shen, Wendy K. Chung, Rudolph L. Leibel

“…Additionally, we identified two individuals (one of whom has a de novo variant) with a heterozygous pLoF variant in a cohort of early onset or extreme obesity and report the clinical histories of these individuals with non-syndromic obesity with no history of neurobehavioral or cognitive disability. The BMI association was replicated in the All of Us whole genome sequencing data. …”
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Evaluating Quality of Life of Parents Having a Child with Disability by Rita Kumari Ban, Iswari Luitel, Kalpana Regmi

“…There is a moderate positive correlation between psychosocial and social domains. Cognitive disability mean score was highest on the social domain that is 14.91and lowest on the physical domain (13.87). …”
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Cognitive functions in middle aged individuals are related to metabolic disturbances and aerobic capacity: a cross-sectional study. by Maria Pedersen, Karin Kaereby Pedersen, Helle Bruunsgaard, Karen Suarez Krabbe, Carsten Thomsen, Kristine Færch, Bente Klarlund Pedersen, Erik Lykke Mortensen

“…These findings emphasize the importance of appropriate lifestyle and not only blood glucose control in prevention of cognitive disability.…”
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Evaluating Quality of Life of Parents Having a Child with Disability by Rita Kumari Ban, Iswari Luitel, Kalpana Regmi

“…There is a moderate positive correlation between psychosocial and social domains. Cognitive disability mean score was highest on the social domain that is 14.91and lowest on the physical domain (13.87). …”
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Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome. by Fiorenza Stagni, Jacopo Magistretti, Sandra Guidi, Elisabetta Ciani, Chiara Mangano, Laura Calzà, Renata Bartesaghi

“…No therapies exist to improve cognitive disability in individuals with DS. In previous studies we demonstrated that pharmacotherapy with fluoxetine restores neurogenesis, granule cell number and dendritic morphology in the DG of the Ts65Dn mouse model of DS. …”
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