Quantification and ACD: Evidence from Real-Time Sentence Processing by Hackl, Martin, Koster-Hale, Jorie, Varvoutis, Jason

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Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs by Wong, Alex Xing Fah

“…Better understanding of the cellular pathways underlying this escape from antimitotic drug-induced cell death, known as mitotic slippage, is crucial for development of combinatorial therapies that can enhance existing treatment regimen in patients. …”
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Analysis of Minimum Interaction Time for Continuous Distributed Interactive Computing by Zhang, Lu, Tang, Xueyan, He, Bingsheng

“…We formulate the Minimum Interaction Time (MIT) problem as a combinatorial problem of these two tuning knobs and prove that it is NP-hard. …”
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Energy-efficient hardware accelerators based on bit-serial graph and memory-centric computing architectures by Mu, Junjie

“…The first half of this thesis demonstrates a novel hardware design for solving combinatorial optimization problems (COPs) with high energy efficiency. …”
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Signal processing on simplicial complexes with vertex signals by Ji, Feng, Kahn, Giacomo, Tay, Wee Peng

“…A graph or a 1-complex is a combinatorial object that models binary relations, which do not directly capture complex high arity relations. …”
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Biomolecular topology: modelling and analysis by Liu, Jian, Xia, Ke-Lin, Wu, Jie, Yau, Stephen Shing-Toung, Wei, Guo-Wei

“…In the past few decades, mathematical concepts, models, algorithms, and tools from algebraic topology, combinatorial topology, computational topology, and topological data analysis, have demonstrated great power and begun to play an essential role in tackling the biomolecular data challenge. …”
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On semidefinite programming relaxations of the traveling salesman problem by De Klerk, Etienne., Pasechnik, Dmitrii V., Sotirov, Renata.

“…Kovačević-Vujčić, Semidefinite programming methods for the symmetric traveling salesman problem, in Proceedings of the 7th International IPCO Conference on Integer Programming and Combinatorial Optimization, Springer-Verlag, London, UK, 1999, pp. 126–136]. …”
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Integrative multi-omics dissection of cancer cell states and susceptibility by Liu, Yunpeng(Biologist)Massachusetts Institute of Technology.

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kboolnet: a toolkit for the verification, validation, and visualization of reaction-contingency (rxncon) models by Carretero Chavez, Willow, Krantz, Marcus, Klipp, Edda, Kufareva, Irina

“…The models are split into reactions, which generate states, and contingencies, that impinge on reactions; this avoids the so-called “combinatorial explosion” of system size. Boolean description of the biological system compensates for the poor availability of kinetic parameters which are necessary for quantitative models. …”
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Quantitative Modeling for Guiding the Transition to Low-Carbon Logistics by Lehmann, Jonas

“…More specifically, we provide a multi-period combinatorial optimization decision-support tool that offers cost-optimal fleet replacement and utilization decisions given a set of decarbonization targets. …”
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Persistent spectral hypergraph based machine learning (PSH-ML) for protein-ligand binding affinity prediction by Liu, Xiang, Feng, Huitao, Wu, Jie, Xia, Kelin

“…Molecular descriptors or fingerprints can be generated from persistent attributes, which are statistical or combinatorial functions of PSH, and combined with machine learning models, in particular, GBT. …”
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Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys by Mockenhaupt, Stefan, Grosse, Stefanie, Rupp, Daniel, Bartenschlager, Ralf, Grimm, Dirk

“…Finally, we demonstrate the power of our vectors for combinatorial RNAi strategies by showing robust suppression of hepatitis C virus (HCV) with an AAV expressing a bifunctional TuD against an anti-HCV shRNA sense strand and an HCV-related cellular miRNA. …”
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Budget feasible mechanism design : from prior-free to Bayesian by Bei, Xiaohui, Chen, Ning, Gravin, Nick, Lu, Pinyan

“…Budget feasible mechanism design studies procurement combinatorial auctions in which the sellers have private costs to produce items, and the buyer (auctioneer) aims to maximize a social valuation function on subsets of items, under the budget constraint on the total payment. …”
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Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation by Li, Guoliang, Ruan, Xiaoan, Auerbach, Raymond K., Sandhu, Kuljeet Singh, Zheng, Meizhen, Wang, Ping, Poh, Huay Mei, Goh, Yufen, Lim, Joanne, Zhang, Jingyao, Sim, Hui Shan, Peh, Su Qin, Mulawadi, Fabianus Hendriyan, Ong, Chin Thing, Orlov, Yuriy L., Hong, Shuzhen, Zhang, Zhizhuo, Landt, Steve, Raha, Debasish, Euskirchen, Ghia, Wei, Chia-Lin, Ge, Weihong, Wang, Huaien, Davis, Carrie, Fisher-Aylor, Katherine I., Mortazavi, Ali, Gerstein, Mark, Gingeras, Thomas, Wold, Barbara, Sun, Yi, Cheung, Edwin, Liu, Edison, Sung, Wing-Kin, Snyder, Michael, Ruan, Yijun, Fullwood, Melissa Jane

“…Most genes with promoter-promoter interactions were active and transcribed cooperatively, and some interacting promoters could influence each other implying combinatorial complexity of transcriptional controls. …”
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Meta-Heuristic Search Based Test Data Generation Method for Dynamic-Functional Testing in Automatic Programming Assessment (S/O 13793) by Romli, Rohaida, Abd Wahab, Alawiyah, Romli, Rusnida, Yusoff, Nooraini

“…Generating a large volume of test data has been identified as leading to issues concerning combinatorial problems. Thus, this research aims to propose a method of generating and locating an adequate test data with optimal in size by adapting a MHST to satisfy the dynamic functional testing in APA namely DyFunFPA-TDG. …”
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In vivo bone marrow microenvironment siRNA delivery using lipid–polymer nanoparticles for multiple myeloma therapy by Guimarães, Pedro PG, Figueroa-Espada, Christian G, Riley, Rachel S, Gong, Ningqiang, Xue, Lulu, Sewastianik, Tomasz, Dennis, Peter S, Loebel, Claudia, Chung, Amanda, Shepherd, Sarah J, Haley, Rebecca M, Hamilton, Alex G, El-Mayta, Rakan, Wang, Karin, Langer, Robert, Anderson, Daniel G, Carrasco, Ruben D, Mitchell, Michael J

“…Here, we utilize both RNA interference (RNAi) and lipid–polymer nanoparticles to engineer a potential MM therapy, which targets CyPA within blood vessels of the bone marrow. We used combinatorial chemistry and high-throughput in vivo screening methods to engineer a nanoparticle platform for small interfering RNA (siRNA) delivery to bone marrow endothelium. …”
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Correction of errors in tandem mass spectrum extraction enhances phosphopeptide identification by Hao, Piliang, Ren, Yan, Sze, Siu Kwan, Tam, James P.

“…Here we propose to identify and correct these errors via the combinatorial use of multiple spectrum extraction tools. …”
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Mathematical foundation of data science by Fang, Xiaowei

“…Later, the method of chaining and the combinatorial reasoning based on the VC dimensionenables us to bound the subgaussian-incremented processes and random quadratic form, extending two applications about empirical processes and statistical learning theory. …”
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Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology by Ahmed, Syed Moiz, Dröge, Peter

“…Intriguingly, a recent large-scale clinical study identifiedHMGA2expression as a sole predicting marker for relapse and poor clinical outcomes in 350 acute myeloid leukemia (AML) patients receiving combinatorial treatments that targeted TOP2 and replicative DNA synthesis. …”
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Programmable morphing, electroactive porous shape memory polymer composites with battery-voltage Joule heating stimulated recovery by Lai-Iskandar, S., Li, Wenhao, Tsang, S. H., Lee, Y. H., Teo, Edwin Hang Tong

“…Our method can be compatible with kirigami techniques for the design of hierarchical and combinatorial shape-change structures. 3DC not only serves as an intrinsic heater but, during synthesis, its cell walls also act as a confinement framework for architecting porosity within 3DC-eSMPCs, which can be actuated with low-voltage (7.5 V, <2 W). …”
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