Clinical confidence following an interprofessional educational program on eating disorders for health care professionals: a qualitative analysis by Pettersen G, Rosenvinge JH, Thune-Larsen KB, Wynn R

“…Gunn Pettersen,1 Jan H Rosenvinge,1 Kari-Brith Thune-Larsen,2 Rolf Wynn1,31Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; 2Oslo University Hospital, Oslo, Norway; 3Division of Addictions and Specialized Services, University Hospital of North Norway, Tromsø, NorwayAbstract: There are an increasing number of educational programs to improve clinical competence and skills to treat mental disorders. For complex disorders there is also a focus on improving the quality of interprofessional work. …”
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Genetic and environmental risk factors of acute infection-triggered encephalopathy by Masashi Mizuguchi, Masashi Mizuguchi, Akiko Shibata, Akiko Shibata, Mariko Kasai, Mariko Kasai, Ai Hoshino, Ai Hoshino

“…Most of the syndromes are complex disorders, caused or aggravated by multiple, genetic and environmental risk factors. …”
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Altered Microstructural Caudate Integrity in Posttraumatic Stress Disorder but Not Traumatic Brain Injury. by Dana Waltzman, Salil Soman, Nathan C Hantke, J Kaci Fairchild, Lisa M Kinoshita, Max Wintermark, J Wesson Ashford, Jerome Yesavage, Leanne Williams, Maheen M Adamson, Ansgar J Furst

“…Thus, DTI appears to be a vital tool to investigate subcortical pathology, greatly enhancing the ability to detect subtle brain changes in complex disorders.…”
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A knowledge-based method for association studies on complex diseases. by Alireza Nazarian, Heike Sichtig, Alberto Riva

“…Complex disorders are a class of diseases whose phenotypic variance is caused by the interplay of multiple genetic and environmental factors. …”
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Shortened Lifespan and Other Age-Related Defects in Bang Sensitive Mutants of Drosophila melanogaster by Elaine R. Reynolds

“…Mitochondrial diseases are complex disorders that exhibit their primary effects in energetically active tissues. …”
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Automated approach for indirect immunofluorescence images classification based on unsupervised clustering method by Letizia Vivona, Donato Cascio, Vincenzo Taormina, Giuseppe Raso

“…Autoimmune diseases (ADs) are a collection of many complex disorders of unknown aetiology resulting in immune responses to self‐antigens and are thought to result from interactions between genetic and environmental factors. …”
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Strain-Specific Liver Metabolite Profiles in Medaka by Hannah Soergel, Felix Loosli, Claudia Muhle-Goll

“…The relationship between genetic variation and phenotypic traits is often poorly understood since specific genotypes do not always easily translate into associated phenotypes, especially for complex disorders. The genetic background has been shown to affect metabolic pathways and thus contribute to variations in the metabolome. …”
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Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers by Alireza Nazarian, Alexander M. Kulminski

“…Almost all complex disorders have manifested epidemiological and clinical sex disparities which might partially arise from sex-specific genetic mechanisms. …”
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Systematic identification of the role of gut microbiota in mental disorders: a TwinsUK cohort study by Julie Delanote, Alejandro Correa Rojo, Philippa M. Wells, Claire J. Steves, Gökhan Ertaylan

“…Abstract Mental disorders are complex disorders influenced by multiple genetic, environmental, and biological factors. …”
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Yoga in major depressive disorder: molecular mechanisms and clinical utility by Madhuri Rajaneesh Tolahunase, Surabhi Gautam, Rajesh Sagar, Manoj Kumar, Rima Dada

“…Since, depression is a complex disorder associated with increased incidence of other complex disorders, it must be treated by an integrated holistic approach that can address the complexity of MDD. …”
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Investigation of Rare Single-Nucleotide PCDH15 Variants in Schizophrenia and Autism Spectrum Disorders. by Kanako Ishizuka, Hiroki Kimura, Chenyao Wang, Jingrui Xing, Itaru Kushima, Yuko Arioka, Tomoko Oya-Ito, Yota Uno, Takashi Okada, Daisuke Mori, Branko Aleksic, Norio Ozaki

“…Recently, rare variants of large effect have been paid attention to understand the etiopathology of these complex disorders. Thus, we evaluated the impacts of rare, single-nucleotide variants (SNVs) in PCDH15 on SCZ or ASD. …”
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Blepharophimosis with intellectual disability and Helsmoortel‐Van Der Aa Syndrome share episignature and phenotype by Sarli, C, van der Laan, L, Reilly, J, Trajkova, S, Carli, D, Brusco, A, Levy, MA, Relator, R, Kerkhof, J, McConkey, H, Tedder, ML, Skinner, C, Alders, M, Henneman, P, Hennekam, RCM, Ciaccio, C, D'Arrigo, S, Vitobello, A, Faivre, L, Weber, S, Vincent‐Devulder, A, Perrin, L, Bourgois, A, Yamamoto, T, Kini, U

“…Distinct DNA methylation profiles referred to as episignatures have been reported in HVDAS and BAF complex disorders. Due to molecular interactions between ADNP and BAF complex, and an overlapping craniofacial phenotype with narrowing of the palpebral fissures in a subset of patients with HVDAS and BIS, we hypothesized the possibility of a common phenotype‐specific episignature. …”

Genetics of parathyroid tumours by Thakker, R

“…Genetic testing is available and of value in the clinical setting, as it helps in making the correct diagnosis and planning the management of these complex disorders associated with parathyroid tumours.…”

UTILIZING VISUAL IMAGES OF AUTISM BEHAVIORAL SYMPTOMS IN FACEBOOK APPLICATION FOR RAISING AN AWARENESS AMONG SECONDARY SCHOOL TEACHERS IN PULAU PINANG by Dolah, Jasni, Baboo, Shanthi Balraj, Mat Desa, Mohd Asyiek, Mohd Bakhir, Norfarizah

“…Autism always misinterpreted and associated with a group of complex disorders of brain development, these disorders are characterized in varying degrees, by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviours. …”
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Utilizing Visual Images Of Autism Behavioral Symptoms In Facebook Application For Raising An Awareness Among Secondary School Teachers In Pulau Pinang by Dolah, Jasni, Balraj Baboo, Shanthi, Mat Desa, Mohd Asyiek, Mohd Bakhir, Norfarizah

“…Autism always misinterpreted and associated with a group of complex disorders of brain development, these disorders are characterized in varying degrees, by difficulties in social interaction, verbal and nonverbal communication and repetitive behaviours. …”
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Effect of increased prolactin and psychosocial stress on erectile function by R. Sajdlova, L. Fiala

“… Introduction Sexual dysfunctions in men are complex disorders that consist of organic and psychogenic components. …”
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Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm. by Janice L Farlow, Hai Lin, Laura Sauerbeck, Dongbing Lai, Daniel L Koller, Elizabeth Pugh, Kurt Hetrick, Hua Ling, Rachel Kleinloog, Pieter van der Vlies, Patrick Deelen, Morris A Swertz, Bon H Verweij, Luca Regli, Gabriel J E Rinkel, Ynte M Ruigrok, Kimberly Doheny, Yunlong Liu, Joseph Broderick, Tatiana Foroud, FIA Study Investigators

“…We demonstrate that sequencing of densely affected families permits exploration of the role of rare variants in a relatively common disease such as IA, although there are important study design considerations for applying sequencing to complex disorders. In this study, we explore methods of WES variant prioritization, including the incorporation of unaffected individuals, multipoint linkage analysis, biological pathway information, and transcriptome profiling. …”
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3D Modeling of the Crystalline Lens Complex under Pseudoexfoliation by Leonor Jud, André P. G. Castro, Rui B. Ruben, Bernardo Feijóo, Filomena J. Ribeiro, Paulo R. Fernandes

“…Pseudoexfoliation, one of the most frequent crystalline lens complex disorders, is prevalent in up to 30% of individuals older than 60 years old. …”
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CalPen (Calculator of Penetrance), a web-based tool to estimate penetrance in complex genetic disorders. by Aditya Addepalli, Sakhare Kalyani, Minali Singh, Debashree Bandyopadhyay, K Naga Mohan

“…Mutations conferring susceptibility to complex disorders also occur in healthy individuals but at significantly lower frequencies than in patients, indicating that these mutations are not completely penetrant. …”
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Adenosine, Schizophrenia and Cancer: Does the Purinergic System Offer a Pathway to Treatment? by Abdul-Rizaq Hamoud, Karen Bach, Ojal Kakrecha, Nicholas Henkel, Xiaojun Wu, Robert E. McCullumsmith, Sinead M. O’Donovan

“…We also highlight the importance of studies examining the adenosine system in this subset of patients for the potential insight they may offer into these complex disorders.…”
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