Introduction to the Proceedings of “Complexity-disorder” days by Lévy Jean-Claude Serge

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Editorial: “Disease-Only” alleles and genotypes in complex disorders? by Mina Ohadi

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Chimeric Structures in Mental Illnesses—“Magic” Molecules Specified for Complex Disorders by Patrycja Kleczkowska

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Pulmonary atresia with intact ventricular septum (PAIVS): Is Nigeria ready for this complex disorder? by B.A. Animasahun, O.A. Ajayi, M.O. Lamina, A.O. Kehinde

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COMPLEX DISORDERS OF HEART RHYTHM AND CONDUCTIVITY IN A PATIENT WITH HYPOTHYROIDISM (CLINICAL OBSERVATION) by L. K. Kozlova, G. B. Kuchma, B. T. Turmukhambetova, E. A. Ibragimova, N. V. Sokolovа, A. P. Shatilov

“…The article describes a clinical case of the occurrence of complex disorders of the heart rhythm and conductivity in a patient of 45 years with decompensated hypothyroidism. …”
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Recent advances in development of nano-carriers for immunogene therapy in various complex disorders by Sanaz Shahgordi, Fatemeh Oroojalian, Ezzat Hashemi, Maryam Hashemi

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Tumor necrosis factor-alpha gene polymorphisms and complex disorders: A study among mendelian population with East Asian Ancestry by Salam Kabita, Priyanka Rani Garg, Masan Kambo Newmei, Kallur Nava Saraswathy, Huidrom Suraj Singh

Subjects: “…Complex disorders…”
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Web-Based Software for Storage, Statistical Processing and Analysis of SNP Data in Studies on Complex Disorders by Betcheva E, Betchev C, Toncheva D

Subjects: “…multifactorial (complex) disorders…”
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Introduction to the Proceedings of the 8th “Complexity-disorder” days: Tribute to Fernand Braudel and Jean Delacour by Levy Jean-Claude Serge

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A Systematic Screening of ADHD-Susceptible Variants From 25 Chinese Parents–Offspring Trios by Qianqian Li, Yingying Meng, Jingyang Wang, Yuhang Xie, Tian Li, Wei Sun

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Coupled mixed model for joint genetic analysis of complex disorders with two independently collected data sets by Haohan Wang, Fen Pei, Michael M. Vanyukov, Ivet Bahar, Wei Wu, Eric P. Xing

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Comparing deep belief networks with support vector machines for classifying gene expression data from complex disorders by Johannes Smolander, Matthias Dehmer, Frank Emmert‐Streib

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T2DiACoD: A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders by Jyoti Rani, Inna Mittal, Atreyi Pramanik, Namita Singh, Namita Dube, Smriti Sharma, Bhanwar Lal Puniya, Muthukurussi Varieth Raghunandanan, Ahmed Mobeen, Srinivasan Ramachandran

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Exploring the association between brain-derived neurotrophic factor levels and longitudinal psychopathological and cognitive changes in Sardinian psychotic patients by Ulker Isayeva, Mirko Manchia, Roberto Collu, Diego Primavera, Luca Deriu, Edoardo Caboni, Novella Iaselli, Davide Sundas, Massimo Tusconi, Federica Pinna, Pasquale Paribello, Maria Scherma, Claudia Pisanu, Anna Meloni, Clement C. Zai, Donatella Congiu, Alessio Squassina, Walter Fratta, Paola Fadda, Bernardo Carpiniello

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Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders by Yuriy Baglaenko, Catriona Wagner, Vijay G. Bhoj, Petter Brodin, M. Eric Gershwin, Daniel Graham, Pietro Invernizzi, Kenneth K. Kidd, Ilya Korsunsky, Michael Levy, Andrew L. Mammen, Victor Nizet, Francisco Ramirez-Valle, Edward C. Stites, Marc S. Williams, Michael Wilson, Noel R. Rose, Virginia Ladd, Marina Sirota

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An integrative network analysis framework for identifying molecular functions in complex disorders examining major depressive disorder as a test case by Anup Mammen Oommen, Stephen Cunningham, Páraic S. O’Súilleabháin, Brian M. Hughes, Lokesh Joshi

“…Highlighting the significant gap that exists in the current literature, the network analysis framework proposed reduces the impact of data gaps and permits the identification of key molecular signatures underlying complex disorders with multiple etiologies such as within MDD and presents multiple treatment options to address their molecular dysfunction.…”
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Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis by Xiao Peng, Rocha-Sanchez Sonia, Liu Yong-Jun, Zhang Yuan-Yuan, Shen Hui, Zhao Lan-Juan, Liu Peng-Yuan, Xiong Dong-Hai, Long Ji-Rong, Dvornyk Volodymyr, Recker Robert R, Deng Hong-Wen

“…<p>Abstract</p> <p>Background</p> <p>Public SNP databases are frequently used to choose SNPs for candidate genes in the association and linkage studies of complex disorders. However, their utility for such studies of diseases with ethnic-dependent background has never been evaluated.…”
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Genome analyses of &gt;200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders by Ligthart, S, Vaez, A, Võsa, U, Stathopoulou, MG, De Vries, PS, Prins, BP, Van Der Most, PJ, Tanaka, T, Naderi, E, Rose, LM, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Macé, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, JP, Abbasi, A, Kacprowski, T, Verweij, N, Smith, AV, Huang, T, Marzi, C, Feitosa, MF, Lohman, KK, Kleber, ME, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikäinen, L-P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, JH, Feenstra, B, Lifelines Cohort Study, Amini, M, Charge Inflammation Working Group, Lahti, J, Schraut, KE, Fornage, M, Suktitipat, B, Chen, W-M, Li, X, Nutile, T, Malerba, G, Luan, J, Bak, T, Schork, N, Del Greco M, F, Thiering, E, Mahajan, A, Marioni, RE, Mihailov, E, Eriksson, J, Ozel, AB, Zhang, W, Nethander, M, Cheng, Y-C, Aslibekyan, S, Ang, W, Gandin, I, Yengo, L, Portas, L, Kooperberg, C, Hofer, E, Rajan, KB, Schurmann, C, Hollander, W, Ahluwalia, TS, Zhao, J, Draisma, HHM, Ford, I, Timpson, N, Teumer, A, Huang, H, Wahl, S, Liu, Y, Huang, J, Uh, H-W, Geller, F, Joshi, PK, Yanek, LR, Trabetti, E, Lehne, B, Vozzi, D, Verbanck, M, Biino, G, Saba, Y, Meulenbelt, I, O'Connell, JR, Laakso, M, Giulianini, F, Magnusson, PKE, Ballantyne, CM, Hottenga, JJ, Montgomery, GW, Rivadineira, F, Rueedi, R, Steri, M, Herzig, K-H, Stott, DJ, Menni, C, Frånberg, M, St Pourcain, B, Felix, SB, Pers, TH, Bakker, SJL, Kraft, P, Peters, A, Vaidya, D, Delgado, G, Smit, JH, Großmann, V, Sinisalo, J, Seppälä, I, Williams, SR, Holliday, EG, Moed, M, Langenberg, C, Räikkönen, K, Ding, J, Campbell, H, Sale, MM, Chen, Y-DI, James, AL, Ruggiero, D, Soranzo, N, Hartman, CA, Smith, EN, Berenson, GS, Fuchsberger, C, Hernandez, D, Tiesler, CMT, Giedraitis, V, Liewald, D, Fischer, K, Mellström, D, Larsson, A, Wang, Y, Scott, WR, Lorentzon, M, Beilby, J, Ryan, KA, Pennell, CE, Vuckovic, D, Balkau, B, Concas, MP, Schmidt, R, De Leon, CF, Bottinger, EP, Kloppenburg, M, Paternoster, L, Boehnke, M, Musk, AW, Willemsen, G, Evans, DM, Madden, PAF, Kähönen, M, Kutalik, Z, Zoledziewska, M, Karhunen, V, Kritchevsky, SB, Sattar, N, Lachance, G, Clarke, R, Harris, TB, Raitakari, OT, Attia, JR, Van Heemst, D, Kajantie, E, Sorice, R, Gambaro, G, Scott, RA, Hicks, AA, Ferrucci, L, Standl, M, Lindgren, CM, Starr, JM, Karlsson, M, Lind, L, Li, JZ, Chambers, JC, Mori, TA, De Geus, EJCN, Heath, AC, Martin, NG, Auvinen, J, Buckley, BM, De Craen, AJM, Waldenberger, M, Strauch, K, Meitinger, T, Scott, RJ, McEvoy, M, Beekman, M, Bombieri, C, Ridker, PM, Mohlke, KL, Pedersen, NL, Morrison, AC, Boomsma, DI, Whitfield, JB, Strachan, DP, Hofman, A, Vollenweider, P, Cucca, F, Jarvelin, M-R, Jukema, JW, Spector, TD, Hamsten, A, Zeller, T, Uitterlinden, AG, Nauck, M, Gudnason, V, Qi, L, Grallert, H, Borecki, IB, Rotter, JI, März, W, Wild, PS, Lokki, M-L, Boyle, M, Salomaa, V, Melbye, M, Eriksson, JG, Wilson, JF, Penninx, BWJH, Becker, DM, Worrall, BB, Gibson, G, Krauss, RM, Ciullo, M, Zaza, G, Wareham, NJ, Oldehinkel, AJ, Palmer, LJ, Murray, SS, Pramstaller, PP, Bandinelli, S, Heinrich, J, Ingelsson, E, Deary, IJ, Mägi, R, Vandenput, L, Van Der Harst, P, Desch, KC, Kooner, JS, Ohlsson, C, Hayward, C, Lehtimäki, T, Shuldiner, AR, Arnett, DK, Beilin, LJ, Robino, A, Froguel, P, Pirastu, M, Jess, T, Koenig, W, Loos, RJF, Evans, DA, Schmidt, H, Smith, GD, Slagboom, PE, Eiriksdottir, G, Morris, AP, Psaty, BM, Tracy, RP, Nolte, IM, Boerwinkle, E, Visvikis-Siest, S, Reiner, AP, Gross, M, Bis, JC, Franke, L, Franco, OH, Benjamin, EJ, Chasman, DI, Dupuis, J, Snieder, H, Dehghan, A, Alizadeh, BZ

Towards Understanding the Genetic Nature of Vasovagal Syncope by Natalia Matveeva, Boris Titov, Elizabeth Bazyleva, Alexander Pevzner, Olga Favorova

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Testing groups of genomic locations for enrichment in disease loci using linkage scan data: A method for hypothesis testing by Avramopoulos Dimitrios, Zandi Peter, Gherman Adrian, Fallin M, Bassett Susan S

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