Stem cell biology needs a theory by Ben D. MacArthur

“…Stem cell biologists are increasingly making use of computational models to decipher their data. However, there is sometimes uncertainty about what makes a “good” model. …”
Get full text

Fluid transients induced vibration in a pipe system by Wang, Zhong Min.

“…The main objectives of the study are to establish a computational model and numerical methods for the coupled phenomena, and hence to evaluate the performance of a long water supply pipeline subject to a strong earthquake load.…”
Get full text

Particulate Matter Forecasting Using Different Deep Neural Network Topologies and Wavelets for Feature Augmentation by Stephanie Lima Jorge Galvão, Júnia Cristina Ortiz Matos, Yasmin Kaore Lago Kitagawa, Flávio Santos Conterato, Davidson Martins Moreira, Prashant Kumar, Erick Giovani Sperandio Nascimento

Get full text

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes by Damian Bartuzi, Ewa Kędzierska, Katarzyna M. Targowska-Duda, Oliwia Koszła, Tomasz M. Wróbel, Simon Jademyr, Tadeusz Karcz, Katarzyna Szczepańska, Piotr Stępnicki, Olga Wronikowska-Denysiuk, Grażyna Biała, Jadwiga Handzlik, Jesper L. Kristensen, Antti Poso, Agnieszka A. Kaczor

Get full text

Killing Many Birds With Two Stones: Hypoxia and Fibrosis Can Generate Ectopic Beats in a Human Ventricular Model by Rafael Sachetto, Rafael Sachetto, Sergio Alonso, Sergio Alonso, Rodrigo Weber dos Santos

“…In this work, we focus on two conditions: hypoxia and fibrosis, which are part of complex pathological modifications that take place in many cardiac diseases (hypertrophic cardiomyopathy, hypertensive heart disease, and recurrent myocardial infarction) and respiratory diseases (obstructive pulmonary disease, obstructive sleep apnea, and cystic fibrosis). Using computational models of cardiac electrophysiology, we evaluate if the interplay between hypoxia and fibrosis is sufficient to trigger cardiac arrhythmia. …”
Get full text

Modeling unveils sex differences of signaling networks in mouse embryonic stem cells by Zeba Sultana, Mathurin Dorel, Bertram Klinger, Anja Sieber, Ilona Dunkel, Nils Blüthgen, Edda G Schulz

Get full text

Effects of small molecules on neurogenesis: Neuronal proliferation and differentiation by Michał K. Jastrzębski, Piotr Wójcik, Piotr Stępnicki, Agnieszka A. Kaczor

Get full text

Impact of post-harvest processing techniques on the glycemic index of millets by Z. Afrose Subaitha, S.R. Priyadarshini, K.S. Yoha, J.A. Moses

Get full text

Computer-based methods for cost estimation of underground electrical cable installation in Singapore by Ho, Teck Hong., Woon, Hin Juan.

“…Firstly, to study the environmental factors affecting the productivity of the works and quantify them formally and, secondly, to develop computer models for estimating the cost of such works.…”
Get full text

Simulation of Fire with a Gas Kinetic Scheme on Distributed GPGPU Architectures by Stephan Lenz, Martin Geier, Manfred Krafczyk

Get full text

Analysis of Drill-String Nonlinear Dynamics Using the Lumped-Parameter Method by Lelya A. Khajiyeva, Igor V. Andrianov, Yuliya F. Sabirova, Askar K. Kudaibergenov

Get full text

Theoretical and Experimental Analysis of a New Process for Forming Flanges on Hollow Parts by Grzegorz Winiarski, Andrzej Gontarz, Grzegorz Samołyk

Get full text

Exergetic Evaluation of an Ethylene Refrigeration Cycle by Francisco Amaral, Alex Santos, Ewerton Calixto, Fernando Pessoa, Delano Santana

Get full text

The Weights Reset Technique for Deep Neural Networks Implicit Regularization by Grigoriy Plusch, Sergey Arsenyev-Obraztsov, Olga Kochueva

Get full text

Humans gradually integrate sudden gain or loss of visual information into spatial orientation perception by Jamie Voros, Victoria Kravets, Kieran Smith, Torin K. Clark

“…It is well-known, and computational models capture, differences in spatial orientation perception with visual information or without (i.e., in the dark). …”
Get full text

Task Offloading Method Based on Cloud-Edge-End Cooperation in Deep Space Environment by SHANG Yuye, YUAN Jiabin

“…Deep space exploration is a significant area of space missions in the modern world,and future large-scale deep space exploration will be greatly impacted by autonomous deep space exploration technologies.The autonomous technology of deep space exploration faces severe challenges because of the complicated and uncharted deep space environment,lengthy deep space communication time,and constrained on-board computing capacity.To address this issue,a cloud-edge-end cooperation architecture for deep space exploration tasks using digital twins is developed,which can offer more efficient resource services for deep space exploration autonomous technologies.Firstly,the complex deep space exploration task is decomposed into multiple sub-modules with dependencies.Secondly,the orbiter coverage time model,the collaborative computing model,and the task dependency model are established in the virtual space layer.Finally,based on the aforementioned models,the corresponding target optimization pro-blem is proposed.The optimization objective is to minimize the energy consumption and time of the landing rover for completing the deep space exploration mission under the constraints of module dependence,the effective communication service time of the orbiter and the transmit power control of the landing rover.In order to solve this optimization problem,an adaptive genetic algorithm is proposed,so that the optimal execution strategy for the landing rover in the physical space layer can be determined.Si-mulation results show that the proposed adaptive genetic algorithm can effectively reduce the mission completion time and energy consumption.Additionally,the proposed cloud-edge-end cooperation computing model is contrasted with the other three computing models,and the results reveal that,when it is used to achieve the same objective,the proposed cloud-edge-end cooperation framework has a greater resource utilization.…”
Get full text

Computational Study of Flow and Heat Transfer Characteristics of EG-Si₃N₄ Nanofluid in Laminar Flow in a Pipe in Forced Convection Regime by Edin Berberović, Siniša Bikić

“…The obtained results from the numerical simulations show very good predicting capabilities of the implemented computational model for the laminar flow coupled to the forced convection heat transfer. …”
Get full text

Enhancing physiologic simulations using supervised learning on coarse mesh solutions by Kolandaivelu, Kumaran, O'Brien, Caroline C., Shazly, Tarek, Kolachalama, Vijaya Bhasker, Edelman, Elazer R

“…Computational modelling of physical and biochemical processes has emerged as a means of evaluating medical devices, offering new insights that explain current performance, inform future designs and even enable personalized use. …”
Get full text
Get full text
Get full text

Mathematical model of activation of transforming growth factor - β1 with application to liver fibrosis progression by Venkatraman, Lakshmi

“…We next built a computational model including both plasmin activation and plasmin mediated TGF-β1 activation. …”
Get full text

MODELING OF UNDERGROUND MINE WORKINGS IN CONSOLIDATING THE SOIL-ARRAY by Dmitry V Velichko, Andrei N Dronov, Alexander A Tereshin

“…The article deals with the analysis of computer modeling of stability of underground workings in the ground array strengthen cement mixtures. …”
Get full text