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3901
iAmideV-Deep: Valine Amidation Site Prediction in Proteins Using Deep Learning and Pseudo Amino Acid Compositions
Published 2021-03-01“…A less costly and efficient alternative is to supplement wet lab experiments with accurate computational models. Hence, an urgent need exists for efficient and accurate computational models to easily identify amidated sites in peptides. …”
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3902
Drug deposition in coronary arteries with overlapping drug-eluting stents
Published 2017“…In situations such as this, computational modeling has proven essential, helping define the limits of efficacy, determine the mode and mechanism of drug release, and identify alternatives to avoid toxicity. …”
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3903
Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling
Published 2018“…Here, we develop a systems approach to integrate time-course metabolomics data with a computational model of metabolism to analyze the metabolic state of naive and primed murine pluripotent stem cells. …”
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3904
Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
Published 2021“…Quantitative proteomics and computational modeling show that ERK pulsing is enabled by rewiring of mitogen-activated protein kinase (MAPK) signaling: from an oncogenic BRAFV600E monomer-driven configuration that is drug sensitive to a receptor-driven configuration that involves Ras-GTP and RAF dimers and is highly resistant to RAF and MEK inhibitors. …”
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3905
Baby Gym: Bridging the Gap between Reinforcement Learning and Human Infant Locomotor Development
Published 2024“…Baby Gym will serve as a first step in enabling a cross-disciplinary open-source ecosystem of computational models to understand infant motor development. …”
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3906
Impact of flow pulsatility on arterial drug distribution in stent-based therapy
Published 2014“…Interestingly, computational models simulating suboptimal deployment settings revealed a complex interplay between arterial drug distribution, Womersley number and the extent of malapposition. …”
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3907
Deep learning for alternative splicing
Published 2019“…In particular, cryptic mutations that cause novel splice junctions to appear deep within introns of genes are very hard to identify. Accurate computational models are therefore crucial for effective diagnosis.…”
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3908
Numerical model validation for mengkulang glulam timber bolt withdrawal capacity
Published 2022“…Due to the high cost of preparing the timber specimen, computer modelling always becomes the alternative in measuring the load-carrying capacity for timber connections. …”
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3909
Waste heat recovery of biomass based industrial boilers by using stirling engine
Published 2022“…For this reason, Computational Fluid Dynamic (CFD) simulation test was performed to design an initial computational model of Stirling engine for low temperature heat waste recovery. …”
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3910
Eye movement control in reading Chinese: A matter of strength of character?
Published 2022-10-01“…Various proposals to explain the underlying mechanisms involved in eye movement control are examined and the paper concludes that the most likely account is of a two-factor process whereby the character is the main driver for longer saccades and that the word plays a role in shorter ones. A computational model is proposed to provide an integrated account of the dynamic interaction of these two factors.…”
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3911
Using Cloud Computing Technology in Libraries: Providing Roadmap
Published 2019-04-01“…Cloud computing is a computational model that provides software and web-based computing resources when requested by users. …”
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3912
Soft Computing: Coping with Complexity
Published 2010-06-01“…While it has been correctly noted that the expression “soft computing” is employed in a variety of senses and characterizations to designate a wide array of technologies, we argue that the original motivation for the introduction of soft-computing methods was the need to cope with the complexity of existing mathematical and computational models of real-world systems. We review this essential motivation contending that other apparent distinguishing characteristics—such as the implicit character of some models—are either artifacts of specific treatments or temporary stages in their evolution towards more sophisticated technologies.…”
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3913
Cloud-based complex of computer transdisciplinary models in the context of holistic educational approach
Published 2019-03-01“…Proper theoretical background for the complex design is elaborated and the process of the computer models development is covered. The models in the complex are grouped in the sections according to the curriculum subjects (Physics, Algebra, Geometry, Biology, Geography, and Informatics). …”
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3914
The EEG Signal Prediction by Using Neural Network
Published 2008-01-01“…The neural network is computational model based on the features abstraction of biological neural systems. …”
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3915
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives
Published 2021-03-01“…The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.…”
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3916
Control of reactor temperature and pressure using cascade control during polyvinyl chloride production
Published 2023-01-01“…Improvement and modernization of the technological process of polyvinyl chloride production requires the appropriate development of computer modelling systems, which ensure the following: identification and maintenance of optimal modes of technological processes that contribute to continuous operation, as well as the use of intelligent systems of modelling and control of technological devices. …”
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3917
Fluid Intelligence Emerges from Representing Relations
Published 2022-08-01“…Based on recent findings in cognitive neuroscience and psychology as well as computational models of working memory and reasoning, I argue that fluid intelligence (fluid reasoning) can amount to representing in the mind the key relation(s) for the task at hand. …”
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3918
The Adhesive Composition with Additives of Carbon Nanomaterials for Aircraft Structures Based on Polymer Composites
Published 2015-09-01“…In the given work, the possibility for application of the nanomodified adhesive composition (NAC) in aircraft structures is investigated. It is shown by computer modeling with the quantum mechanics method that open edged carbon nanotubes are an effective additive for increasing of the shear mechanical parameters of the adhesive composition based on the epoxy matrix. …”
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3919
On the use of flexible formworks for concrete structures
Published 2023-12-01“…Advantages and disadvantages of the formwork system are discussed and the article concludes with the perspective of future studies on the construction process through computational models.…”
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3920
The Art of Mathematical Biology: a Foreword for the Launch of BIOMATH
Published 2012-10-01“…Academic institutions and funding agencies increasingly recognize the interdisciplinary nature of biology and medicine, including the important role mathematical, statistical and computational modeling play in the analysis and interpretation of data and information. …”
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