-
7121
To supplement or not to supplement: a metabolic network framework for human nutritional supplements.
Published 2013-01-01“…Similar to any study in a model organism, the computational modeling of this research has some limitations. …”
Get full text
Article -
7122
In Silico Analysis of the MitraClip in a Realistic Human Left Heart Model
Published 2023-09-01“…By predicting possible adverse events and complications in a patient-specific manner, computational modeling supports evidence-based decision making and enhances the overall effectiveness and safety of transcatheter mitral valve repairs.…”
Get full text
Article -
7123
Intersection and Flattening of Surfaces in 3D Models through Computer-Extended Descriptive Geometry (C<span style="font-variant: small-caps">e</span>DG)
Published 2023-04-01“…Computer-extended Descriptive Geometry (C<span style="font-variant: small-caps;">e</span>DG) is a new approach to solving and building computer models of three-dimensional (3D) geometrical systems through descriptive geometry procedures (thus inheriting invariant-symmetry properties from projective geometry) that have demonstrated reliability and accuracy. …”
Get full text
Article -
7124
Modeling the Temperature Field in Frozen Soil under Buildings in the City of Salekhard Taking into Account Temperature Monitoring
Published 2022-07-01“…The proposed approach, based on a combination of the soil temperature monitoring and computer modeling methods, can be used to improve geotechnical monitoring methods.…”
Get full text
Article -
7125
Experimental and Simulation Modal Analysis of a Prismatic Battery Module
Published 2020-04-01“…Additionally, a proper computational model for simulations of battery module also plays a key role in correctly predicting the dynamic response of battery packs. …”
Get full text
Article -
7126
Computational 3D Modeling-Based Identification of Inhibitors Targeting Cysteine Covalent Bond Catalysts for JAK3 and CYP3A4 Enzymes in the Treatment of Rheumatoid Arthritis
Published 2023-12-01“…Eight possible inhibitors were found, and six new inhibitors were designed in silico using these computational models. The pharmacokinetic and safety characteristics of these candidates were thoroughly assessed. …”
Get full text
Article -
7127
A Highly Configurable High-Level Synthesis Functional Pattern Library
Published 2021-02-01“…In this paper, we propose a set of functional patterns libraries based on the MapReduce model, implemented by C++ templates, which can quickly implement high-performance parallel pipelined computing models on FPGA with specified simple parameters. …”
Get full text
Article -
7128
Modeling of long-term train loads impacts on subgrade soils: a review
Published 2023-09-01“…We describe the stages of creating the subgrade computer modelling taking into account the analysis of trains load impact, the properties of model’s structural layers, and the change of soil properties under long-term loads.…”
Get full text
Article -
7129
Optimizing Size Consistency in Batch Roller Production: A Mixed Strategy Approach
Published 2023-09-01“…To elucidate the operational principles of DCMS, we have developed a computational model grounded in DDSGL, designed simulation test plans under different mixing parameters, and summarized the number of direct comparisons, total comparisons, and differences in roller cycle times to determine the optimal combination of mixing parameters. …”
Get full text
Article -
7130
Real-space observation of ergodicity transitions in artificial spin ice
Published 2023-09-01“…In condensed matter physics, ergodicity remains a concept largely investigated via theoretical and computational models. Here, we demonstrate the direct real-space observation of ergodicity transitions in a vertex-frustrated artificial spin ice. …”
Get full text
Article -
7131
Computational assessment of hybrid nanofluid flow with the influence of hall current and chemical reaction over a slender stretching surface
Published 2022-12-01“…The flow distribution takes into consideration the effects of variable magnetic fields, heat production, Hall current and chemical reactions. A computational model is established for the purpose to amplify the energy communication rate and enhance the productivity and performance of thermal energy propagation for several industrial and biological purposes. …”
Get full text
Article -
7132
Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets
Published 2023-02-01“…Although the blockade of GPVI function is widely recognized as a potent anti-thrombotic approach, there are limited studies focused on site-specific targeting of GPVI. Using computational modeling and bioinformatics, we analyzed collagen- and CRP-binding surfaces of GPVI monomers and dimers, and compared the interacting surfaces with other mammalian GPVI isoforms. …”
Get full text
Article -
7133
Using network analysis to identify leverage points based on causal loop diagrams leads to false inference
Published 2023-11-01“…This application of network analysis, employed to quantitatively identify leverage points without having to use computational modelling approaches that translate CLDs into sets of mathematical equations, has however not been duly reflected upon. …”
Get full text
Article -
7134
New advances in the computational simulation of Aqueous Homogeneous Reactor for medical isotopes production
Published 2021-02-01“…Accordingly, this paper aims to show the advances made to improve the predictive capabilities during the multi-physics computational modeling of AHRs.…”
Get full text
Article -
7135
Multilayer In Vitro Human Skin Tissue Platforms for Quantitative Burn Injury Investigation
Published 2023-02-01“…This information is needed to elucidate high-temperature, short-duration burn injury kinetics and enables determination of relevant input parameters for computational models to facilitate treatment planning. Multilayer in vitro skin platforms were constructed using human dermal keratinocytes and fibroblasts embedded in collagen I hydrogels. …”
Get full text
Article -
7136
Adopted walking condition for computational simulation approach on bearing of hip joint prosthesis: review over the past 30 years
Published 2022-12-01“…Appropriate selection and addition of gait cycles in computation modelling are crucial for accurate and reliable prediction and analysis of bearing performance such as wear a failure of implants. …”
Get full text
Article -
7137
A disease-related essential protein prediction model based on the transfer neural network
Published 2023-01-01“…Due to high costs of traditional biological experiments, an improved Transfer Neural Network (TNN) was designed to extract raw features from multiple biological information of proteins first, and then, based on the newly-constructed Transfer Neural Network, a novel computational model called TNNM was designed to infer essential proteins in this paper. …”
Get full text
Article -
7138
From Monitoring and Modeling to Management: How to Improve Water Quality in Brazilian Rivers? A Case Study: Piabanha River Watershed
Published 2021-01-01“…Thus, simulations of the river water quality have been performed through computational modeling suggesting organic load reductions in some sub-basins. …”
Get full text
Article -
7139
Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view
Published 2023-11-01“…To characterize the interactions between Aβ and HCC, we used a complementary approach based on the combination of small-angle neutron scattering analysis, atomic force microscopy and computational modelling, allowing the exploration of the structures of multicomponent protein complexes. …”
Get full text
Article -
7140
Numerical Investigation of Darcy–Forchheimer Hybrid Nanofluid Flow with Energy Transfer over a Spinning Fluctuating Disk under the Influence of Chemical Reaction and Heat Source
Published 2022-12-01“…The present computational model is built to analyze the energy and mass transition rate through a copper and cobalt ferrite water-based hybrid nanofluid (hnf) flow caused by the fluctuating wavy spinning disk. …”
Get full text
Article