Learning separate visual representations of independently rotating objects. by Tromans, J, Page, H, Stringer, S

“…How the brain is able to develop neurons that exhibit these object selective responses poses a significant challenge for computational models of object recognition. Typically, many objects make up a complex natural scene and are never presented in isolation. …”

Deep brain stimulation abolishes slowing of reactions to unlikely stimuli by Antoniades, C, Bogacz, R, Kennard, C, Fitzgerald, J, Aziz, T, Green, A

“…The cortico–basal–ganglia circuit plays a critical role in decision making on the basis of probabilistic information. Computational models have suggested how this circuit could compute the probabilities of actions being appropriate according to Bayes' theorem. …”

Economic value biases uncertain perceptual choices in the parietal and prefrontal cortices. by Summerfield, C, Koechlin, E

“…We then used the computational model to generate trial-by-trial estimates of decision-related evidence that were based on combined sensory and economic information (the decision variable or DV), and regressed these against fMRI activity recorded whilst participants performed the task. …”

The origin of heredity in protocells by West, T, Sojo, V, Pomiankowski, A, Lane, N

“…Here we develop a computational model that examines one of the first major biological innovations-the origin of heredity in simple protocells. …”

Cellular Open Resource (COR): A public CellML based environment for modeling biological function by Garny, A, Kohl, P, Noble, D

“…Computer models have proved to be invaluable to experimental and theoretical research in cardiac electrophysiology, and several environments have been designed to aim at easing the development of such models. …”

Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front. by McLennan, R, Schumacher, L, Morrison, J, Teddy, J, Ridenour, D, Box, A, Semerad, C, Li, H, McDowell, W, Kay, D, Maini, P, Baker, R, Kulesa, P

“…Multiplexed imaging of mRNA expression using fluorescent hybridization chain reaction (HCR) quantitatively confirmed the expression profiles of lead cells. Computational modeling predicted that a small fraction of lead cells that detect directional information is optimal for successful stream migration. …”

Rare-earth/transition-metal magnets at finite temperature: Self-interaction-corrected relativistic density functional theory in the disordered local moment picture by Patrick, CE, Staunton, JB

“…Atomic-scale computational modeling of technologically relevant permanent magnetic materials faces two key challenges. …”

Dynamics of large-scale electrophysiological networks: a technical review by O'Neill, G, Tewarie, P, Vidaurre, D, Liuzzi, L, Woolrich, M, Brookes, M

“…Finally, we review some existing developments that, by using realistic computational models, pursue a deeper understanding of the underlying causes of non-stationary connectivity.…”

Temporal expectation improves the quality of sensory information. by Rohenkohl, G, Cravo, A, Wyart, V, Nobre, A

“…We used a psychophysical paradigm and computational modeling to investigate the mechanisms by which temporal expectation can modulate visual perception. …”

Infant categorization as a dynamic process linked to memory by Althaus, N, Gliozzi, V, Mayor, J, Plunkett, K

“…We explore recency effects in infant categorization, which does not merely involve memory for individual items, but the formation of abstract category representations. We present a computational model of infant categorization that simulates category learning in 10-month-olds. …”

Post-movement beta activity in sensorimotor cortex indexes confidence in the estimations from internal models by Tan, H, Wade, C, Brown, P

“…Current theories about the function of the PMBS have been focused on either the closure of motor response or the processing of sensory afferance. Computational models of sensorimotor control have emphasized the importance of the integration between feedforward estimation and sensory feedback, and therefore the putative motor and sensory functions of beta oscillations may reciprocally interact with each other and in fact be indissociable. …”

Dissociable sources of uncertainty in perceptual decision making by Michael, E

“…We will present a computational model that can account for the independent behavioural effects of these two sources of uncertainty by assuming that categorical decisions are made on the basis of a probabilistic transformation of perceptual evidence. …”

SURFACE CHEMICAL PROCESSES IN METAL ORGANIC MOLECULAR-BEAM EPITAXY - GA DEPOSITION FROM TRIETHYLGALLIUM ON GAAS(100) by Murrell, A, Wee, A, Fairbrother, D, Singh, N, Foord, J, Davies, G, Andrews, D

“…A reaction scheme is proposed to account for the observations and kinetic parameters are obtained from computer modeling of the temperature-programmed desorption results. …”

A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana. by Muraro, D, Larrieu, A, Lucas, M, Chopard, J, Byrne, H, Godin, C, King, J

“…Since these hormones interact at different levels of spatial organisation, we develop a multi-scale computational model which enables us to study the interplay between these signalling networks and cell-cell communication during the specification of the root meristem. …”

Receptor concentration and diffusivity control multivalent binding of Sv40 to membrane bilayers by Szklarczyk, O, González-Segredo, N, Kukura, P, Oppenheim, A, Choquet, D, Sandoghdar, V, Helenius, A, Sbalzarini, I, Ewers, H

“…To determine the role of receptor diffusion, concentration and the number of receptors required for stable binding in this interaction, we analyze the binding of SV40 to GM1 in supported membrane bilayers by computational modeling based on experimental data. We measure the diffusion rates of SV40 virions in solution by fluorescence correlation spectroscopy and of the receptor in bilayers by single molecule tracking. …”

Modeling the outcome of structural disconnection on resting-state functional connectivity. by Cabral, J, Hugues, E, Kringelbach, M, Deco, G

“…In this work, we propose a computational model to investigate the role of a structural disconnection (encompassing putative local/global and axonal/synaptic mechanisms) on the organizational properties of emergent functional networks. …”

From bench to bedside in neuropsychology by Demeyere, N

“…He leaves a tremendous legacy, in many research domains within psychology and neuroscience, including neuropsychology, cognitive psychology, computational modeling, social neuroscience, neuro-rehabilitation and cognitive screening and diagnostics. …”

Deep brain stimulation abolishes slowing of reactions to unlikely stimuli. by Antoniades, C, Bogacz, R, Kennard, C, FitzGerald, J, Aziz, T, Green, A

“…The cortico-basal-ganglia circuit plays a critical role in decision making on the basis of probabilistic information. Computational models have suggested how this circuit could compute the probabilities of actions being appropriate according to Bayes' theorem. …”

Biophysical determinants of transcranial magnetic stimulation: effects of excitability and depth of targeted area. by Stokes, M, Barker, A, Dervinis, M, Verbruggen, F, Maizey, L, Adams, R, Chambers, C

“…We also found similar effects of distance in motor and visual areas, which did not correlate across participants. Computational modeling suggests that the relationship between the effect of distance and the induced electric field is effectively linear within the range of distances that have been explored empirically. …”

Highly stable single-strand-specific 3′-nuclease/nucleotidase from Legionella pneumophila by Trundová, M, Kovaľ, T, Owens, R, Fejfarová, K, Dušková, J, Kolenko, P, Dohnálek, J

“…Bioinformatic and experimental analysis, together with computer modeling and electrostatics calculations point to an unusually high positive charge on the enzyme surface under optimal conditions for catalysis. …”