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7681
Disruption of Network Synchrony and Cognitive Dysfunction After Traumatic Brain Injury
Published 2016-05-01“…This requires the tools of systems neuroscience, including electrophysiological analysis of ensemble neuronal activity and circuitry changes in awake animals after TBI, as well as computational modeling of the effects of TBI on these networks. …”
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7682
A learning-based method to predict LncRNA-disease associations by combining CNN and ELM
Published 2022-03-01“…It is imperative to construct reliable and efficient computational models as addition for practice. Deep learning technologies have been proved to make impressive contributions in many areas, but the feasibility of it in bioinformatics has not been adequately verified. …”
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7683
Does temporal discounting explain unhealthy behavior? A systematic review and reinforcement learning perspective
Published 2014-03-01“…We propose that the burgeoning development of computational models of these processes will permit further identification of health decision-making phenotypes.…”
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7684
Experimental and biophysical modeling of transcription and translation dynamics in bacterial- and mammalian-based cell-free expression systems
Published 2024-04-01“…Current modeling approaches mainly focus on the characterization of E. coli-based CFE systems, a computational model that can be utilized for both bacterial- and mammalian-based CFE has not been investigated. …”
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7685
In Silico Therapeutic Study: The Next Frontier in the Fight against SARS-CoV-2 and Its Variants
Published 2024-01-01“…Nonetheless, diverse computational models exist that offer an opportunity for the swift development of new drugs or the repurposing of old drugs. …”
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7686
Numerical analysis of dengue transmission model using Caputo–Fabrizio fractional derivative
Published 2024-01-01“…The semi-analytical results are then investigated using iterative techniques such as Laplace-Adomian decomposition method. Computational models are utilized to support analytical experiments and enhance the credibility of the results. …”
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7687
Electrophysiological and computational analysis of Cav3.2 channel variants associated with familial trigeminal neuralgia
Published 2022-11-01“…Simulation of neuronal electrical membrane potential using a computational model of reticular thalamic neuron suggests that TN-associated Cav3.2 variants could enhance neuronal excitability. …”
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7688
Task Offloading Strategy for Unmanned Aerial Vehicle Power Inspection Based on Deep Reinforcement Learning
Published 2024-03-01“…Secondly, we established a computational model concerning energy consumption and task processing latency in the UAV power inspection system, enhancing our understanding of the trade-offs involved in UAV offloading strategies. …”
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7689
In defense of local descriptor-based few-shot object detection
Published 2024-02-01“…State-of-the-art image object detection computational models require an intensive parameter fine-tuning stage (using deep convolution network, etc). with tens or hundreds of training examples. …”
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7690
Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration
Published 2022-04-01“…Here, using a combination of immunocytochemistry, single cell biosensors, and computational modeling, we show that Nrf2 functions as a phenotypic stability factor for hybrid E/M cells by inhibiting a complete epithelial-mesenchymal transition (EMT) during collective cancer migration. …”
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7691
HybridGCN for protein solubility prediction with adaptive weighting of multiple features
Published 2023-12-01“…Addressing the imperative to enhance production efficiency and curtail experimental costs, the demand arises for computational models adept at accurately predicting solubility based on provided datasets. …”
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7692
Improving the quality of electricity supply systems in stationary objects of railway transport
Published 2022-04-01“…On the basis of computer modeling, it is shown that the use of suction transformers with a return wire and 25 kV lines with a grounded phase makes it possible to improve the quality of the electric power industry in the power supply systems of stationary objects of railway transport.…”
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7693
Model predictive control of an electrically-heated steam methane reformer
Published 2024-03-01“…The overall dynamic process model is then used in a computational model predictive control (MPC) scheme to drive the process to a new H2 production set-point under unperturbed and steam flowrate disturbance cases. …”
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7694
Myogenic and cortical evoked potentials vary as a function of stimulus pulse geometry delivered in the subthalamic nucleus of Parkinson’s disease patients
Published 2023-08-01“…Such effects are most often attributed to electrical current spread beyond the target region. Prior computational modeling studies have suggested that changing the degree of asymmetry of the individual phases of the biphasic, stimulus pulse may allow for more selective activation of neural elements in the target region. …”
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7695
Patterns of cell division, cell differentiation and cell elongation in epidermis and cortex of Arabidopsis pedicels in the wild type and in erecta.
Published 2012-01-01“…To understand the regulation and coordination of these processes, we studied the temporal behavior of epidermal and cortex cells in Arabidopsis pedicels and used computational modeling to analyze cell behavior in tissues. …”
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7696
Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody
Published 2024-12-01“…Here, we combined X-ray crystallography with computational modeling to predict regions of an anti-glucagon receptor (GCGR) IgG1 antibody prone to self-interaction. …”
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7697
Visible fluorescence of biological fluids as a renal failure marker: New integrative approach
Published 2015-07-01“…Six kinds of nitrogen-free particles (412 ≤ M ≤ 456 Da) were observed in each substance and possible computer models of those have been composed. It is established that along with nitrogen-containing advanced glycation end products (AGEs) also nitrogen-free carbon–oxygen–hydrogen particles (probably toxic) with the composition and structure related to GO can exist in biofluids. …”
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7698
Research on en route capacity evaluation model based on aircraft trajectory data
Published 2023-02-01“…The proposed model envisages three innovations: (ⅰ) the definition of airspace accessible capacity with reference to capacity of road traffic, (ⅱ) the computation model for flux-based airspace accessible capacity and en route accessible capacity, and (ⅲ) two indicators of en route characteristics named instantaneous density and spatial flow are introduced for evaluating the micro-state of the en route. …”
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7699
Ground Slope Stability Analysis
Published 2023-01-01“…The geometric scheme of the computational model was built on transverse profiles. The width of the calculated area was chosen in such a way that there were no changes in the stress-strain state of the array due to the introduction of artificial boundary conditions along the edges of the finite element grid. …”
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7700
A Bayesian model for chronic pain
Published 2022-09-01“…Chronic pain emerges when prior beliefs and likelihoods are biased towards inferring pain from a wide range of sensory data that would otherwise be perceived as harmless. We present a computational model of interoceptive inference and pain experience. …”
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