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7801
Synergistic Effect of Doxorubicin and siRNA-Mediated Silencing of Mcl-1 Using Cationic Niosomes against 3D MCF-7 Spheroids
Published 2021-04-01“…Mcl-1 silencing markedly decreased the viability of MCF-7 cells and triggered apoptosis. Moreover, computer modeling suggested that the combination of doxorubicin (Dox) and Mcl-1 siRNA exhibited a synergistic relationship and enabled a dose reduction of each agent at 1.71 and 3.91 folds, respectively, to reach a 90% inhibitory effect when compared to single-agent treatments. …”
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7802
Modeling of the Wind/Disk Outflow from Be Stars II: Formation of the Keplerian Disk
Published 2022-11-01“…Computer modeling of the outflow from Be stars is performed. …”
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7803
Data Balance Algorithm Based on Histogram in MapReduce
Published 2018-06-01“…MapReduce model is a typical distributed computing model, which is widely used in large-scale data processing, and its performance depends largely on the data distribution status. …”
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7804
An in-silico analysis of experimental designs to study ventricular function: A focus on the right ventricle.
Published 2022-09-01“…Additional in-silico experiments using multiscale computational models have provided further details into biventricular mechanics and hemodynamic function in the presence of PH, yet few have assessed whether model parameters are practically identifiable prior to data collection. …”
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7805
The use of specialized software for liquid radioactive material spills simulation to teach students and postgraduate students
Published 2022-03-01“…It is determined that the existing software tools for radiation exposure assessment do not comprehensively cover features of such events and possess number of shortcomings regarding accidents modeling with spillage of radioactive liquids indoors. Computer modeling and forecasting examples for hypothetical event related to liquid radioactive spill in the JRODOS system are presented. …”
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7806
iRG-4mC: Neural Network Based Tool for Identification of DNA 4mC Sites in Rosaceae Genome
Published 2021-05-01“…The iRG-4mC predictor outperformed the existing state-of-the-art computational model by an accuracy difference of 9.95% on <i>F. vesca</i> (training dataset), 8.7% on <i>R. chinesis</i> (training dataset), 6.2% on <i>F. vesca</i> (independent dataset) and 10.6% on <i>R. chinesis</i> (independent dataset). …”
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7807
Modeling effects of intrinsic and extrinsic rewards on the competition between striatal learning systems
Published 2013-10-01“…In this work, we extend a computational model of the prefrontal and dorsolateral striatal reinforcement learning systems to account for the effects of extrinsic and intrinsic rewards. …”
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7808
CURRENT CONTROL OF Z-SOURCE FOUR-LEG INVERTER FOR AUTONOMOUS PHOTOVOLTAIC SYSTEM BASED ON MODEL PREDICTIVE CONTROL
Published 2021-07-01“…Methods: mathematical and computer modeling using the MatLab/Simulink software environment. …”
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7809
Echo State Property upon Noisy Driving Input
Published 2024-01-01“…The echo state property (ESP) is a key concept for understanding the working principle of the most widely used reservoir computing model, the echo state network (ESN). The ESP is achieved most of the operation time under general conditions, yet the property is lost when a combination of driving input signals and intrinsic reservoir dynamics causes unfavorable conditions for forgetting the initial transient state. …”
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7810
Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition
Published 2022-03-01“…The corresponding NA was recorded using high-density multi-electrode arrays and correlated to capillary dynamics through a computational model dissecting the main components of granular layer activity. …”
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7811
Numerical Modeling Using Immersed Boundary-Lattice Boltzmann Method and Experiments for Particle Manipulation under Standing Surface Acoustic Waves
Published 2023-01-01“…The steady-state placements obtained in the computational model and experiments exhibit excellent agreement and are reported.…”
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7812
Sustaining the healthcare systems through the conceptual of biomedical engineering: A study with recent and future potentials
Published 2023-03-01“…Biomedical engineering offers software for simulation, 3D motion-catching and printing technologies for computer modelling and engineering. The discipline of biomedical engineering is a fast-moving, cross-disciplinary field covering medicine, biology, chemistry, engineering, nanotechnology and informatics. …”
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7813
Research into Dissociation Zones of Gas Hydrate Deposits with a Heterogeneous Structure in the Black Sea
Published 2021-03-01“…These data are used for the computer modelling of the dissociation zone in the Surfer-8.0 software package based on the data interpolation method, which uses three methods for calculating the volumes of modelling bodies. …”
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7814
Computational demystification of iron carbonyls formation under syngas environment
Published 2024-02-01“…In this work, we demystify using multiscale computational modeling the mechanism of Iron pentacarbonyl formation: Density functional theory (DFT) is used to explore various catalytic reactions that involve a Fe adatom reacting with adsorbed carbon monoxide. …”
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7815
Punching shear strength under static and dynamic loads
Published 2023-01-01“…This is due to the lack of computational models in which all the acting internal forces ensuring the resistance of the interface to penetration would be considered comprehensively. …”
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7816
Top-down inputs drive neuronal network rewiring and context-enhanced sensory processing in olfaction.
Published 2019-01-01“…We developed a biophysically supported computational model for the rewiring of the top-down projections and the intra-bulbar network via adult neurogenesis. …”
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7817
Neural network technology for identifying defect sizes in half-plane based on time and positional scanning
Published 2020-10-01“…The authors have developed a technique for restoring the parameters of a defect based on the computational modeling and ANN. Materials and Methods. The problem is solved in the flat setting through the finite element method (FEM). …”
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7818
The Impact of Electrical Energy Consumption on the Payback Period of a Rooftop Grid-Connected Photovoltaic System: A case Study from Vietnam
Published 2022-05-01“…The main goal of this study is to develop a computational model and investigate the effect of electrical energy consumption on the payback period of rooftop GCPV systems. …”
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7819
Simulation of an emergency situation of a digital architecture object
Published 2023-01-01“…At the 2nd stage, this element was switched off from work, and a computational model was obtained for simulating an emergency. …”
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7820
A Systematic Approach to the Model Development of Reactors and Reforming Furnaces With Fuzziness and Optimization of Operating Modes
Published 2023-01-01“…Comparison of the obtained results of computer modeling and optimization with the results of known deterministic models shows the advantages of the proposed approach in the face of scarcity and fuzziness of the initial information. …”
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