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8641
Multiple neuron clusters on Micro-Electrode Arrays as an in vitro model of brain network
Published 2023-09-01“…Hence, our multi-network dissociated cortical assemblies suggest the relevance of pacemaker neurons as essential elements for generating brain network electrophysiological patterns; indeed, such evidence should be considered in the development of computational models for envisaging network behavior both in physiological and pathological conditions.…”
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8642
Formic Acid Production via One-Pot Hydrolysis-Oxidation of Starch over Quaternary Ammonium Salts of Vanadium-Containing Keggin-Type Heteropoly Acids
Published 2022-10-01“…The highest formic acid yield of 50% was achieved over the best [(C<sub>2</sub>H<sub>5</sub>)<sub>4</sub>N]<sub>3.5</sub>H<sub>0.5</sub>PVMo<sub>11</sub>O<sub>40</sub> catalyst, which was active and stable in seven reaction cycles. The kinetic computational model, which described formic acid formation well, was proposed in the presence of the most active [(C<sub>2</sub>H<sub>5</sub>)<sub>4</sub>N]<sub>3.5</sub>H<sub>0.5</sub>PVMo<sub>11</sub>O<sub>40</sub> catalyst.…”
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8643
The Effects of Using a Trombe Wall Modified with a Phase Change Material, from the Perspective of a Building’s Life Cycle
Published 2023-11-01“…A comprehensive computational model of a residential building located in Rzeszów, Poland, was created, taking into account the thermal parameters of the analyzed structure of the wall and its operation under real, specific climatic conditions, as well as the environmental characteristics. …”
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8644
Prognostic Value of CD8+ Lymphocytes in Hepatocellular Carcinoma and Perineoplastic Parenchyma Assessed by Interface Density Profiles in Liver Resection Samples
Published 2023-01-01“…We conclude that (1) our computational models reveal independent and opposite prognostic impacts of CD8+ cell densities at the interfaces of the malignant and non-malignant epithelium interfaces with the surrounding stroma; and (2) together with pathology, surgery, and laboratory data, comprehensive prognostic models can be constructed to predict patient outcomes after liver resection due to HCC.…”
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8645
Simulating a lead-cooled reactor campaign using the EUCLID/V1 code
Published 2022-12-01“…The authors have developed a fuel archive to store calculated data in HDF5 format, created a computational model editor to generate input data in the fuel archive format, and also provided an example of computing the campaign of a lead-cooled fast reactor for three core design models shown in this paper. …”
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8646
Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1
Published 2021-09-01“…We used the novel signal transduction pathway activity (STA) computational model to quantify the functional NFκB pathway output in primary MM PC from diverse patient subsets at multiple stages of disease. …”
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8647
Tetracyclic 1,4-Naphthoquinone Thioglucoside Conjugate U-556 Blocks the Purinergic P2X7 Receptor in Macrophages and Exhibits Anti-Inflammatory Activity In Vivo
Published 2023-08-01“…Naphthoquinone-thioglucoside conjugate <b>U-556</b> binding to the extracellular part of the P2X7R was confirmed by SPR analysis, and the kinetic characteristics of this complex formation were established. Computer modeling predicted that <b>U-556</b> binds the P2X7R allosteric binding site, topographically similar to that of the specific A438079 blocker. …”
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8648
Deep learning and multi-omics approach to predict drug responses in cancer
Published 2022-11-01“…By using molecular profiles of cancer cell lines available from Cancer Cell Line Encyclopedia (CCLE) and anticancer drug responses available in the Genomics of Drug Sensitivity in Cancer (GDSC), we will build computational models to predict anticancer drug responses from molecular features. …”
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8649
A Coupled Geochemical‐Geodynamic Approach for Predicting Mantle Melting in Space and Time
Published 2022-04-01“…Here, BDD21's functionality is illustrated using the Fluidity computational modeling framework, although it is designed so that it can be integrated with other geodynamic software. …”
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8650
An interactive analysis of the mouse oviductal miRNA profiles
Published 2022-10-01“…Here, an exhaustive bibliography search was carried out, followed by the construction of a computational model based on the networks theory in an attempt to recreate and elucidate the pathways potentially activated by the oviductal miRNA. …”
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8651
Active reinforcement learning versus action bias and hysteresis: control with a mixture of experts and nonexperts.
Published 2024-03-01“…With systematic comparison and falsification of computational models, human choices were tested for signatures of parallel modules representing not only an enhanced form of generalized reinforcement learning but also action bias and hysteresis. …”
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8652
Theoretical calculation of the adiabatic electron affinities of the monosubstituted benzaldehyde derivatives
Published 2023-07-01“…In the current study, several computational models were examined to calculate accurate adiabatic electron affinity (AEA) of twelve m- and p-monosubstituted benzaldehyde derivatives. …”
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8653
A risk measurement tool for targeted HIV prevention measures amongst young pregnant and lactating women in South Africa
Published 2022-06-01“…Model coefficients were rounded and stratified into risk groups and the area under the receiver operating curve (AUROC) was computed. Models were developed to determine which risk factors provided the most predictive accuracy whilst remining clinically meaningful. …”
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8654
Comprehensive mechanical performance characteristics of newly developed ultra-thin coronary stents
Published 2023-11-01“…These two stent designs are engineered with distinct bridge size and distribution patterns, prioritizing enhanced flexibility irrespective of the strut thickness. Computational modeling results show anticipated stress distribution with maximum local stresses, which are compared with experimental outcomes conducted in this study. …”
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8655
A Deep-Learning-Based Multi-Modal Sensor Fusion Approach for Detection of Equipment Faults
Published 2022-11-01“…Developed sensor data acquisition technologies allow for digitally generating and storing many types of sensor data. Data-driven computational models allow the extraction of information about the machine’s state from acquired sensor data. …”
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8656
Fault tolerant trust based task scheduler using Harris Hawks optimization and deep reinforcement learning in multi cloud environment
Published 2023-11-01“…Abstract Cloud Computing model provides on demand delivery of seamless services to customers around the world yet single point of failures occurs in cloud model due to improper assignment of tasks to precise virtual machines which leads to increase in rate of failures which effects SLA based trust parameters (Availability, success rate, turnaround efficiency) upon which impacts trust on cloud provider. …”
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8657
Methodology of the Digital Platform of Smart Accurate Ecologically Balanced Agriculture of Adygea
Published 2022-02-01“…For the first time, an automated computational model of the redistribution of agrochemical indicators in morphometrically classified quasi–homogeneous relief surfaces – geotopes in comparison with soil conditions, climatic and microclimatic fluctuations has been created. …”
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8658
THE EXPERIMENTAL-RATED METHOD OF STYDYING OF WIDE-CHORD FAN OF THE AIRCRAFT ENGINE FOR THE ABSENCE OF FLUTTER
Published 2020-08-01“…It is proposed to use the studied points with a proven absence of flutter for verification of computational models using software systems and methods, for calculating the absence of flutter, taking into account the limits of possible operation defined in the method. …”
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8659
PyRates-A code-generation tool for modeling dynamical systems in biology and beyond.
Published 2023-12-01“…Together, these tools offer a versatile framework for applying computational modeling and numerical analysis methods to dynamical systems in biology and beyond.…”
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8660
A spatial-attentional mechanism underlies action-related distortions of time judgment
Published 2024-02-01“…Furthermore, computational modeling based on the attention measure can reproduce the temporal binding effect. …”
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