-
8681
A novel experimental design for the measurement of metacarpal bone loading and deformation and fingertip force
Published 2018-09-01“…Conclusion This study demonstrates a new method for measuring force and strain experienced by the metacarpal, and fingertip force in cadaveric digits that can, in turn, inform computation models. Inter-individual variation in loads experienced by the third digit suggest that there are differences in joint contact and/or internal bone structure across individuals that are important to consider in clinical and evolutionary contexts.…”
Get full text
Article -
8682
Application of Laboratory Tests in Numerical Analysis for Exhaust Emissions in Business Jet Engines
Published 2023-08-01“…The correspondence of the results showed the correctness of the computational model built, thus predestining it for use in further analysis. …”
Get full text
Article -
8683
Intelligent Technologies and Robotic Machines for Garden Crops Cultivation
Published 2021-12-01“…(Materials and methods) The research methodology was based on such modern methods as computer modeling and programming. In particular, the following methods were applied: systems analysis, artificial neural networks theory, pattern recognition, digital signal processing. …”
Get full text
Article -
8684
On Memristors for Enabling Energy Efficient and Enhanced Cognitive Network Functions
Published 2022-01-01“…Two important properties essential in assuring cost-efficient computer networks and supporting new challenging network scenarios are operating energy efficient and supporting cognitive computational models. These requirements are hard to fulfill without challenging the current architecture behind network packet processing elements such as routers and switches. …”
Get full text
Article -
8685
Advances in non-invasive biosensing measures to monitor wound healing progression
Published 2022-09-01“…We also discuss high-resolution, advanced imaging techniques, which go beyond traditional confocal and fluorescence microscopy to visualize microscopic details of the composition of the wound matrix, linearity of collagen, and live tracking of components within the wound microenvironment. Computational modeling of the wound matrix, including partial differential equation datasets as well as machine learning models that can serve as powerful tools for physicians to guide their decision-making process are discussed.…”
Get full text
Article -
8686
TLNPMD: Prediction of miRNA-Disease Associations Based on miRNA-Drug-Disease Three-Layer Heterogeneous Network
Published 2022-07-01“…Then, this heterogeneous network was converted into three two-layer heterogeneous networks, for each of which the network path computational model was employed to predict association scores. …”
Get full text
Article -
8687
Toward a more informative representation of the fetal–neonatal brain connectome using variational autoencoder
Published 2023-05-01“…Consequently, conventional linear computational models may not adequately capture these accelerated and complex neurodevelopmental trajectories during this critical period of brain development along the prenatal-neonatal continuum. …”
Get full text
Article -
8688
The cancer survival index—A prognostic score integrating psychosocial and biological factors in patients diagnosed with cancer or haematologic malignancies
Published 2022-09-01“…Indicators significantly associated with survival were combined to compute models for the identification of patient groups with different risks of death. …”
Get full text
Article -
8689
PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting.
Published 2019-07-01“…Our approach accounts for recent findings concerning TALE targeting, including frame-shift binding by repeats of aberrant lengths, and the flexible strand orientation of target boxes relative to the transcription start of the downstream target gene. The computational model can account for dependencies between adjacent RVD positions. …”
Get full text
Article -
8690
Perceptual Decision Impairments Linked to Obsessive-Compulsive Symptoms are Substantially Driven by State-Based Effects
Published 2022-05-01“…Computational models of decision making have identified a relationship between obsessive-compulsive symptoms (OCS), both in the general population and in patients, and impairments in perceptual evidence accumulation. …”
Get full text
Article -
8691
Design protein-protein interaction network and protein-drug interaction network for common cancer diseases: A bioinformatics approach
Published 2020-01-01“…Result: Based upon our computational model, a total of 10 common genes: TP53, EGFR, TNF, APOE, VEGFA, IL6, TGFB1, MTHFR, ERBB2, and ESR1 were observed. …”
Get full text
Article -
8692
The coming Omicron waves and factors affecting its spread after China reopening borders
Published 2023-09-01“…To fill this gap, this study innovates a combination of the Erdos Renyl network, modified computational model $$SEIRS$$ SEIRS , and python code instead of only mathematical formulas or computer simulations in the previous studies. …”
Get full text
Article -
8693
Degradation and sorption of the herbicide pelargonic acid in subsoils below railway tracks compared to a range of topsoils
Published 2024-01-01“…Organic carbon normalized adsorption coefficients (KFoc) ranged from 11 to 371 mL/g (all soils) and were pH dependent, consistent with the behaviour of weak acids. Computer modelling using the software PELMO and a set of scenarios for herbicide use on railway tracks developed for the authorisation in Germany yielded predicted environmental concentrations in groundwater of < 0.001 µg/L when parameterised with the adsorption and degradation endpoints from subsoils. …”
Get full text
Article -
8694
P System with Fractional Reduction
Published 2023-07-01“…Membrane computing is a branch of natural computing, which is a new computational model abstracted from the study of the function and structure of living biological cells. …”
Get full text
Article -
8695
Mitigating Computer Limitations in Replicating Numerical Simulations of a Neural Network Model With Hodgkin-Huxley-Type Neurons
Published 2022-05-01“…Even using a simple computational model, the numerical replicability was very difficult to be achieved, requiring people with computational expertise to be performed. …”
Get full text
Article -
8696
Risk assessment of paleo-bio-contamination of landscapes resulting from permafrost degradation by the example of reindeer pastures in the Republic of Sakha (Yakutia)
Published 2022-07-01“…The possibility of ranking agro-landscape zones (using computer modeling) according to the risks of potential epizootics and epidemics associated with bio-contamination has been demonstrated. …”
Get full text
Article -
8697
An In Vitro and In Silico Perspective Study of Seed Priming with Zinc on the Phytotoxicity and Accumulation Pattern of Arsenic in Rice Seedlings
Published 2022-07-01“…The results of the current investigation are rationally significant and may be the pioneering beginning of an exciting and useful method of integrating physiological and biochemical analysis together with a computational modelling approach for evaluating the stress modulating effects of Zn<sup>2+</sup> seed priming on As-induced responses in developing rice seedlings.…”
Get full text
Article -
8698
Deciphering the therapeutic role of Kigelia africana fruit in erectile dysfunction through metabolite profiling and molecular modelling
Published 2023-01-01“…This study focused on profiling the bioactive constituents of Kigelia africana fruit (KAF) using spectroscopic techniques and providing the computational models of their interactions with phosphodiesterase (PDE5) and Rho-associated coiled-coil containing protein kinase 2 (ROCK2) targets associated with erectile dysfunction. …”
Get full text
Article -
8699
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
Published 2022-02-01“…We also report a novel computational model that incorporates empirically determined fitness landscapes at varying drug concentrations, combined with antimalarial susceptibility profiles, mutation rates, and drug pharmacokinetics. …”
Get full text
Article -
8700
An Integrated Workflow for Building Digital Twins of Cardiac Electromechanics—A Multi-Fidelity Approach for Personalising Active Mechanics
Published 2022-03-01“…Personalised computer models of cardiac function, referred to as cardiac digital twins, are envisioned to play an important role in clinical precision therapies of cardiovascular diseases. …”
Get full text
Article