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9061
Numerical Analysis of Transcranial Magnetic Stimulation Application in Patients With Orofacial Pain
Published 2022-01-01“…In this paper, we monitored the accuracy of non-navigated application of repetitive Transcranial Magnetic Stimulation (rTMS) in 10 patients suffering from orofacial pain by using functional magnetic resonance (fMRI), computer modeling and numerical simulation. Through a unique process, each fMRI scan was used to define a Region of Interest (ROI) where the source of the orofacial pain was located, which was to be stimulated using rTMS. …”
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9062
Mathematical Modeling of Lymph Node Drainage Function by Neural Network
Published 2021-11-01“…The use of the presented computational models will allow for a more realistic description and prediction of the immune cell circulation, cytokine distribution and drug pharmacokinetics in humans under various health and disease states as well as assisting in the development of artificial LN-on-a-chip technologies.…”
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9063
Double-Lumen Endotracheal Tube—Predicting Insertion Depth and Tube Size Based on Patient’s Chest X-ray Image Data and 4 Other Body Parameters
Published 2022-12-01“…In this study, we aimed to predict DLT ‘depths’ and ‘sizes’ applied earlier on a group of patients (<i>n</i> = 231) using a computer modeling approach. First, for these patients we retrospectively determined the correlation coefficient (r) of each of the 17 body parameters against ‘depth’ and ‘size’. …”
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9064
Predicting human design decisions with deep recurrent neural network combining static and dynamic data
Published 2020-01-01“…Computational modeling of the human sequential design process and successful prediction of future design decisions are fundamental to design knowledge extraction, transfer, and the development of artificial design agents. …”
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9065
Modeling displacement flow inside a full-length casing string for well cementing
Published 2024-03-01“…While computer modeling of annular displacement efficiency is widely applied in cementing engineering, modeling the displacement flow inside a casing or drill string for cementing operations has received less attention. …”
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9066
Perceptual warping exposes categorical representations for speech in human brainstem responses
Published 2023-04-01“…These findings were not observed in the stimulus acoustics nor model FFR responses generated via a computational model of cochlear and auditory nerve transduction, confirming a central origin to the effects. …”
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9067
Cerebellum Involvement in Dystonia During Associative Motor Learning: Insights From a Data-Driven Spiking Network Model
Published 2022-06-01“…Here, we simulated the cerebellar input-output relationship with high-resolution computational modeling. We used a data-driven cerebellar Spiking Neural Network and simulated a cerebellum-driven associative learning task, Eye-Blink Classical Conditioning (EBCC), which is characteristically altered in relation to cerebellar lesions in several pathologies. …”
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9068
Multi-scale in silico and ex silico mechanics of 3D printed cochlear implants for local drug delivery
Published 2024-01-01“…We used in silico computational models and ex silico experiments to study the mechanics of our newly designed implants when subjected to torsion mimicking the foreseeable implantation procedure. …”
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9069
Computational Analysis of Water-Submerged Jet Erosion
Published 2021-05-01“…The Finnie erosion model was implemented in ANSYS-Fluent 19.2 and used for erosion prediction. The computational model was validated against experimental data and the distributions of the erosion depth as well as the locations of the of maximum and minimum erosion points are well matched. …”
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9070
Pressurized metered-dose inhalers using next-generation propellant HFO-1234ze(E) deposit negligible amounts of trifluoracetic acid in the environment
Published 2023-11-01“…We quantified yield of TFA from HFO-1234ze(E) using a computational model under Europe-relevant atmospheric conditions. …”
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9071
Destruction of Fibroadenomas Using Photothermal Heating of Fe<sub>3</sub>O<sub>4</sub> Nanoparticles: Experiments and Models
Published 2020-08-01“…On the basis of the optical and structural results, we obtained the optical absorption coefficient of the Fe<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>3</mn></msub></semantics></math></inline-formula>O<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>4</mn></msub></semantics></math></inline-formula> NPs via predictions based on the Mie scattering theory and integrated it into a computational model to predict in-vivo thermal damage profiles of NP-embedded fibroadenomas located within a multi-tissue breast model and irradiated with near-infrared 810 nm laser. …”
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9072
Unified framework based parallel FEM code for simulating marine seismoacoustic scattering
Published 2023-01-01“…The method and technologies used in this code includes: 1) Unified framework for acoustic-solid-poroelastic interaction analysis, in which seawater and dry bedrock are considered as generalized saturated porous media with porosity equals to one and zero, respectively, and the coupling between seawater, saturated seabed and dry bedrock can be analyzed in the unified framework of generalized saturated porous media and avoid interaction between solvers of different differential equation; 2) Element-by-element strategy and voxel finite-element method (VFEM), with these strategies, it only needs to calculate several classes of element matrix and avoid assembling and storing the global system matrices, which significantly reduces the amount of memory required; 3) Domain-partitioning procedure and parallel computation technology, it performs 3D and 2D model partitioning for the 3D and 2D codes respectively, sets up the velocity structure model for the partitioned domain on each CPU or CPU core, and calculates the seismic wave propagation in the domain using Message Passing Interface data communication at each time step; 4) Local transmitting boundary condition, we adopt multi-transmitting formula, which is independent of specific wave equations, to minimize reflections from the boundaries of the computational model. A horizontal layered model with the plane P-wave incident vertically from bottom is used to demonstrate the computational efficiency and accuracy of our code. …”
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9073
Learning in Transcriptional Network Models: Computational Discovery of Pathway-Level Memory and Effective Interventions
Published 2022-12-01“…Rational control of dynamic pathway function using stimuli derived from computational models opens the door to empirical studies of proto-cognitive capacities in unconventional embodiments and suggests numerous possible applications in biomedicine, where behavior shaping of pathway responses stand as a potential alternative to gene therapy.…”
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9074
SWAT model calibration for hydrological modeling using concurrent methods, a case of the Nile Nyabarongo River basin in Rwanda
Published 2023-10-01“…The outcomes point out that SUFI-2 outperformed the other algorithms for SWAT calibration, requiring fewer computing model runs and producing the best results. ParaSol established residing the least effective algorithm. …”
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9075
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities
Published 2023-05-01“…Abstract Life science studies involving clustered regularly interspaced short palindromic repeat (CRISPR) editing generally apply the best-performing guide RNA (gRNA) for a gene of interest. Computational models are combined with massive experimental quantification on synthetic gRNA-target libraries to accurately predict gRNA activity and mutational patterns. …”
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9076
Multi-dimensional hydrological–hydraulic model with variational data assimilation for river networks and floodplains
Published 2022-08-01“…The forward-inverse multi-D computational model is successfully validated on virtual and real cases of increasing complexity, including using the second-order scheme version. …”
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9077
Encapsulation and Delivery of Mitoxantrone Using Zirconium-Based Metal–Organic Frameworks (MOFs) and Their Cytotoxic Potential in Breast Cancer Cells
Published 2024-02-01“…The interaction between MTX and the MOFs was also proposed based on computational modelling, suggesting a stronger interaction of UiO-66NH2 and MTX, and an optimised interaction of MTX in the tetrahedral and octahedral pores of the MOFs. …”
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9078
Current Knowledge and Challenges of Particle Size Measurements of Mainstream E-Cigarette Aerosols and Their Implication on Respiratory Dosimetry
Published 2023-02-01“…Lastly, while computational models of particle deposition have been adopted to profile the deposition of e-cigarette mainstream emissions, existing models have limited applicability and generality when dealing with e-cigarette aerosols that have high volatility and hygroscopicity, which can dynamically evaporate or grow during the transport process. …”
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9079
Entropy–Based Diversification Approach for Bio–Computing Methods
Published 2022-09-01“…This area is mainly devoted to designing computational models based on natural phenomena to address complex problems. …”
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9080
Reliability-based structural assessment of historical masonry arch bridges: The case study of Cernadela bridge
Published 2023-07-01“…Finally, the measured inner geometry of the arches was introduced in the computational model through Bayesian inference procedures. …”
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