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9641
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9642
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9643
Planning support systems for spatial planning through social learning
Published 2013Get full text
Thesis -
9644
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9645
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9646
Functional measurements of ear pathology in patients and cadaveric preparations
Published 2014Get full text
Thesis -
9647
Two dimensional particle-in-cell simulation model for Hall type thrusters
Published 2005Get full text
Thesis -
9648
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9649
Exercise under artificial gravity - experimental and computational approaches
Published 2015Get full text
Thesis -
9650
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9651
Novel phases and phase transitions in models of epithelial tissues
Published 2023“…An alternative approach would be to coarse-grain these bio-processes and identify physical phenomena that arise, and model these tissues using simple computational models. Several physical properties have thus been identified that are deemed essential for regulation of epithelial mechanics, such as, cell density, cell-cell interactions, cell shapes, cell propulsion and external factors such as mechanical stress. …”
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Thesis-Doctor of Philosophy -
9652
In-situ monitoring of aerosol jet printing
Published 2024“…The methodology embraces a holistic perspective, incorporating a blend of theoretical analysis, experimental validation, and computational modelling to offer a granular understanding of the underlying mechanisms that govern material flow, deposition dynamics, and defect formation within the AJP process. …”
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Final Year Project (FYP) -
9653
Modelling behavior in agent based simulations of crowds
Published 2015“…However, existing computational models fail to take into consideration the large body of work on human behavior during emergencies and make unsubstantiated assumptions like perfect knowledge of the layout and immediate evacuation on hearing a fire alarm. …”
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Thesis -
9654
Novel metallic transparent conductive layers for optoelectronics
Published 2018“…A non-lithographic approach to fabrication of the transparent conductive AINP mesh was presented based on electrochemical anodizing of AI bulk layer. Computational models for estimating the optical and electronic properties of nanostructured metallic TCLs was proposed founded on the finite-difference time-domain (FDTD) method and the percolation theory, respectively,· and brought to good agreement with experimental data. …”
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Thesis -
9655
Structural studies on DNP binding antibodies
Published 1983“…In addition the aglycosylated molecule becomes much more susceptible to proteolytic digestion. A computational model-building analysis of the quaternary structure of Fc allows an explanation of at least some of the effects of aglycosylation in terms of reduced conformational stability of the C<sub>H</sub>2 domains.…”
Thesis -
9656
Unsupervised learning and continual learning in neural networks
Published 2021“…<p>For decades research has pursued the ambitious goal of designing computer models that learn to solve problems as effectively as humans can. …”
Thesis -
9657
Optimising the surveillance and control of communicable diseases: the effects of population heterogeneity on early outbreak transmission dynamics
Published 2023“…Here, we use <em>Xylella fastidiosa</em> infection in <em>Olea europaea</em> (European olive) as a current high-profile case study to inform the construction of a computational model of pathogen transmission and surveillance. …”
Thesis -
9658
The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection
Published 2017“…In the course of these analyses I have demonstrated the critical influence of the viral backbone, including HIV clade, in combination with particular viral variants, on VRC. Computational modelling analysis has been applied to facilitate understanding of the mechanism by which certain mutants affect the stability of interactions between HLA and viral capsid protein. …”
Thesis -
9659
Human in silico drug trials demonstrate higher accuracy than animal models in predicting clinical pro-arrhythmic cardiotoxicity
Published 2017“…Current animal models raise ethical and translational questions, and have limited accuracy in clinical risk prediction. Human-based computer models constitute a fast, cheap and potentially effective alternative to experimental assays, also facilitating translation to human. …”
Journal article -
9660
Novel germline JAK2R715T mutation causing PV-like erythrocytosis in 3 generations. Amelioration by Ropeg-Interferon
Published 2024“…Her mother and her son similarly had erythrocytosis and a <em>JAK2</em><sup>R715T</sup> mutation. Computer modeling indicated gain-of-function JAK2 activity. …”
Journal article