Deep Neural Network Model of Hearing-Impaired Speech-in-Noise Performance by Haro, Stephanie, Smalt, Christopher J., Ciccarelli, Gregory A., Quatieri, Thomas F.

“…In this study, we propose a computational model that accounts forthe complex interactions between different hearing damagemechanisms and simulateshuman speech-in-noise perception. …”
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Reliable Sensory Processing in Mouse Visual Cortex through Cooperative Interactions between Somatostatin and Parvalbumin Interneurons by Rikhye, Rajeev Vijay, Yildirim, Murat, Han, Ming-Hu, Breton-Provencher, Vincent, Sur, Mriganka

“…Our results, supported by computational models, suggest that somatostatin interneurons increase pyramidal neuron reliability by suppressing parvalbumin interneurons via the inhibitory SST→PV circuit. …”
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Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs by Patil, Kiran M., Ong, Alan Ann Lerk, Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Yuan, Zhen, Meng, Zhenyu, Shu, Zhiyu, Zhang, Haiping, Lu, Lanyuan, Lu, Yunpeng, Chen, Gang

“…Furthermore, our experimental and computational modelling data suggest that PNA·RNA2 triplexes may be stabilized by incorporating a BrUL step but not an LBrU step, in dsRNA-binding PNAs.…”
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Rainfall modeling using two different neural networks improved by metaheuristic algorithms by Sammen, Saad Sh., Kisi, Ozgur, Mohammad Ehteram, Mohammad Ehteram, El-Shafie, Ahmed, Al-Ansari, NadhirAl-Ansari, Ghorbani, Mohammad Ali, Ahmad Bhat, Shakeel, Ahmed, Ali Najah, Shahid, Shamsuddin

“…Six hybrid soft computing models, including multilayer perceptron (MLP)–Henry gas solubility optimization (HGSO), MLP–bat algorithm (MLP–BA), MLP–particle swarm optimization (MLP–PSO), radial basis neural network function (RBFNN)–HGSO, RBFNN–PSO, and RBFGNN–BA, were used in this study to forecast monthly rainfall at two stations in Malaysia (Sara and Banding). …”
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Tuning the ionic character of sodium dodecyl sulphate via counter-ion binding: An experimental and computational study by Germán Pérez-Sánchez, Nicolas Schaeffer, Tamar L. Greaves, Jorge F. B. Pereira, João A. P. Coutinho

“…The CG-MD simulation framework developed in this work captured the role of [N4,4,4,4]+ in the micellar phase transition whilst improving the results obtained with preceding computer models for which the limitations on capturing SDS and [N4,4,4,4]Cl mixtures in aqueous solutions are also shown in detail.…”
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Impact of vaccination and non-pharmacological interventions on COVID-19: a review of simulation modeling studies in Asia by Karan Thakkar, Julia Regazzini Spinardi, Jingyan Yang, Moe H. Kyaw, Egemen Ozbilgili, Carlos Fernando Mendoza, Helen May Lin Oh

“…We reviewed published computational (mathematical/simulation) models conducted in Asia that assessed impacts of pharmacological and non-pharmacological interventions against COVID-19 and their implications for vaccination strategy.MethodsA search of the PubMed database for peer-reviewed, published, and accessible articles in English was performed up to November 2022 to capture studies in Asian populations based on computational modeling of outcomes in the COVID-19 pandemic. …”
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Use of magnetic nanotrap particles in capturing Yersinia pestis virulence factors, nucleic acids and bacteria by Alexandra N. Ii, Shih-Chao Lin, Benjamin Lepene, Weidong Zhou, Kylene Kehn-Hall, Monique L. van Hoek

“…We were able to computationally model the interaction of LcrV with the CN3080 Nanotrap dye and found that it had a low delta-G, suggesting high affinity. …”
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Modal analysis of computational human brain dynamics during helmeted impacts by Fargol Rezayaraghi, Javid Abderezaei, Efe Ozkaya, Devlin Stein, Aymeric Pionteck, Mehmet Kurt

“…After simulating the impact tests using a brain FE model, we calculated the dynamic modes of this computational model for the whole brain, corpus callosum, brainstem, and cerebellum. …”
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Restricted T-Cell Repertoire in the Epicardial Adipose Tissue of Non-ST Segment Elevation Myocardial Infarction Patients by Daniela Pedicino, Anna Severino, Anna Severino, Gabriele Di Sante, Gabriele Di Sante, Maria Cristina De Rosa, Davide Pirolli, Ramona Vinci, Ramona Vinci, Vincenzo Pazzano, Ada F. Giglio, Francesco Trotta, Giulio Russo, Aureliano Ruggio, Eugenia Pisano, Alessia d’Aiello, Francesco Canonico, Francesco Canonico, Pellegrino Ciampi, Domenico Cianflone, Lorenzo Cianfanelli, Maria Chiara Grimaldi, Simone Filomia, Nicola Luciani, Nicola Luciani, Franco Glieca, Franco Glieca, Piergiorgio Bruno, Piergiorgio Bruno, Massimo Massetti, Massimo Massetti, Francesco Ria, Francesco Ria, Filippo Crea, Filippo Crea, Giovanna Liuzzo, Giovanna Liuzzo

“…We then used computational modeling studies to predict interactions of the TCR beta chain variable region (TRBV) and explore sequence alignments. …”
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Pervasive Lying Posture Tracking by Parastoo Alinia, Ali Samadani, Mladen Milosevic, Hassan Ghasemzadeh, Saman Parvaneh

“…First, can we design a single-sensor, pervasive, and inexpensive system that can accurately detect lying postures? Second, what computational models are most effective in the accurate detection of lying postures? …”
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Association between perfluoroalkyl and polyfluoroalkyl internal exposure and serum α-Klotho levels in middle-old aged participants by Min Li, Min Li, Yuanlin Ma, Wenli Cheng, Luyun Zhang, Cheng Zhou, Wenji Zhang, Wenjuan Zhang

“…Quantile-based g-computation models were used to assess the effects of mixed PFAS exposure on serum α-Klotho levels.ResultsThe weighted geometric mean of serum α-Klotho was 791.38 pg/mL for the subjects during 2013–2016. …”
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Prediction of bird-beak configuration in thoracic endovascular aortic repair preoperatively using patient-specific finite element simulations by Negin Shahbazian, PhD, David A. Romero, PhD, Thomas L. Forbes, MD, Cristina H. Amon, ScD

“…Conclusions: Computational simulations of TEVAR accurately predicted the proximal position of a deployed stent graft and the presence of bird-beak preoperatively. The computational models were able to predict the length and angle of bird-beak configurations with good accuracy. …”
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SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner by Lorenzo Moroni, Fulvio Barbaro, Florian Caiment, Orla Coleman, Sabine Costagliola, Giusy Di Conza, Lisa Elviri, Stefan Giselbrecht, Christian Krause, Carlos Mota, Marta Nazzari, Stephen R. Pennington, Annette Ringwald, Monica Sandri, Simon Thomas, James Waddington, Roberto Toni

“…Supporting the “Adverse Outcome Pathway” concept, proteogenomic analysis and biological computational modelling of the underlying mode of action of the tested EDs will be pursued to gain a mechanistic understanding of the chain of events from exposure to adverse toxic effects on thyroid function. …”
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Understanding development of jugular bulb stenosis in vein of galen malformations: identifying metrics of complex flow dynamics in the cerebral venous vasculature of infants by Sara Hadad, Shivani D. Rangwala, Shivani D. Rangwala, Jeffrey N. Stout, Fernando Mut, Darren B. Orbach, Darren B. Orbach, Juan R. Cebral, Alfred P. See, Alfred P. See

“…Discussion: Advanced metrics of flow complexity identified in computational models may reflect observed flow phenomena not fully characterized by primary or secondary hemodynamic parameters. …”
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Server consolidation: A technique to enhance cloud data center power efficiency and overall cost of ownership by Mueen Uddin, Mohammed Hamdi, Abdullah Alghamdi, Mesfer Alrizq, Mohammad Sulleman Memon, Maha Abdelhaq, Raed Alsaqour

“…The cloud computing paradigm is instigated from grid and parallel computing models as it uses virtualization, server consolidation, utility computing, and other computing technologies and models for providing better information technology solutions for large-scale computational data centers. …”
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Numerical Investigations of a Non-Uniform Stator Dihedral Design Strategy for a Boundary Layer Ingestion (BLI) Fan by Tianyu Pan, Kaikai Shi, Hanan Lu, Zhiping Li, Jian Zhang

“…Then, to find the appropriate dihedral design parameters, the full-annulus BLI fan was discretized into several portions according to the rotor blade number and the dihedral design parameter investigations for dihedral depth and dihedral angle were conducted at the portion with the largest inflow distortion through a single-blade-passage computational model. The optimal combinational dihedral design parameter (dihedral depth 0.3, dihedral angle 6 deg) was applied to the blade passages with notable flow loss which were mainly located in the annulus positions from −120 to 60 degrees suffering from inlet distortion, while the blades in the low-loss annulus locations were unchanged. …”
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Transcutaneous Pulsed RF Energy Transfer Mitigates Tissue Heating in High Power Demand Implanted Device Applications: In Vivo and In Silico Models Results by Mohammad L. Karim, Antonio M. Bosnjak, James McLaughlin, Paul Crawford, David McEneaney, Omar J. Escalona

“…Subsequent data analysis and separate computer modelling studies permit understanding of the contribution of tissue blood perfusion towards cooling of the subcutaneous tissue around the electromagnetic coupling area. …”
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Evaluation and Comparison of Moment-to-Force Ratio of a New “PRP Loop” with that of Opus Loop and L Loop- A Finite Element Method Study by Smita Kumari, Priyanka Niranjane, Pallavi Daigavane, Ranjit Kamble

“…Materials and Methods: An in-vitro study was conducted by using FEM analysis in DMIHER University with technical assistance from the Department of Mechanical Engineering VNIT Nagpur. Computer models of Loops design were prepared on Analysis of Systems (ANSYS) version 10 (V10) software. …”
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Recombinant Pseudomonas growing on non-natural fluorinated substrates shows stress but overall tolerance to cytoplasmically released fluoride anion by Anthony G. Dodge, Calvin J. Thoma, Madeline R. O’Connor, Lawrence P. Wackett

“…The defluorinase was shown to have complete enantioselectivity for (S)-fluoro substrates via experimental and computational modeling methods. The bacterium grew to a high turbidity with stoichiometric release of fluoride from the (S)-enantiomers into the medium. …”
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Elucidating the Role of Noncovalent Interactions in Favipiravir, a Drug Active against Various Human RNA Viruses; a ¹H-¹⁴N NQDR/Periodic DFT/QTAIM/RDS/3D Hirs... by Jolanta Natalia Latosińska, Magdalena Latosińska, Janez Seliger, Veselko Žagar, Tomaž Apih, Paweł Grieb

“…Three nuclear quadrupole resonance experimental techniques, namely ¹H-¹⁴N cross-relaxation, multiple frequency sweeps, and two-frequency irradiation, followed by solid-state computational modelling (density functional theory supplemented by the quantum theory of atoms in molecules, 3D Hirshfeld Surfaces, and reduced density gradient) approaches were applied. …”
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