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9861
Ice crystal icing in gas turbine engines
Published 2018“…This thesis describes the development and validation of a new comprehensive computational model to aid prediction of ice crystal icing in turbofan compressors. …”
Thesis -
9862
The complexity of meta-computational problems
Published 2020“…We show that this barrier applies to many current instantiations of hardness magnification, that involve a wide range of restricted computational models.</p> <p>Next we consider learnability, and initiate a top-down study of hardness of learning circuit classes, i.e. we consider hardness of learning circuit classes more powerful than P/poly. …”
Thesis -
9863
Hardness magnification for natural problems
Published 2018“…We show that for several natural problems of interest, complexity lower bounds that are barely non-trivial imply super-polynomial or even exponential lower bounds in strong computational models. We term this phenomenon "hardness magnification". …”
Conference item -
9864
Development of fuzzy logic for demand response and storage management in hybrid energy system
Published 2019“…The first objective of this thesis is to develop an existing computational model for optimising the sizing of micro-scale HES using Particle Swarm Optimisation (PSO). …”
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Thesis -
9865
A study on thermal environmental performance in atria in the tropics with special reference to Malaysia
Published 2007“…The combined research methods are as follows: developing a conceptual low energy atrium form based on the vernacular design features to be used for computer modelling studies; calTying out field measurement and monitoring on an existing atrium building which provides validation data for dynamic thermal simulation program TAS: modelling exercise on the same monitored building using dynamic thermal modelling to develop confidence in cOlTectly modelling thermal stratification within the multi-level atrium: employing dynamic thermal modelling to model representative atrium forms (i.e. both side-lit and top-lit model) and examine quantitatively the effects of some of the key design parameters (i.e. wall-to-roof void area, roof overhangs, and internal solar blinds) on the thermal comfort and energy performance in atria due to both full natural ventilation and pressurised ventilation; and utilising computational Ouid dynamics (CFD) to complement the dynamic thermal simulation results, and to investigate quantitatively the thermal and ventilation performance within the atrium well in response to the changes of design parameters (i.e. varying the inlet to outlet opening area ratio and outlet" s alTangement). …”
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Thesis -
9866
Simulation of the effects of bank vegetation on velocity profiles in a meandering compound channel
Published 2021“…The presence of vegetation significantly increased the level of complexity in cross-over regions, which contributed to high difference between model and measurement. In computational model, the effects are more significant during low relative depth. …”
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Thesis -
9867
Leadless biventricular left bundle and endocardial lateral wall pacing versus left bundle only pacing in left bundle branch block patients
Published 2022-12-01“…Both pacing methods can be delivered through leadless pacing, to avoid risks associated with endocardial or transvenous leads. We used computational modelling to quantify synchrony induced by BIV-endo pacing and LBP through a leadless pacing system, and to investigate how the right-left ventricle (RV-LV) delay, RV lead location and type of left bundle capture affect response. …”
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9868
Molecular Mechanism of Zinc-Dependent Oligomerization of Alzheimer’s Amyloid-β with Taiwan (D7H) Mutation
Published 2023-07-01“…In this study, the D7H-Aβ metal binding domain (D7H-Aβ<sub>16</sub>) has been used as a model to establish the molecular mechanism of zinc-induced D7H-Aβ oligomerization through turbidimetry, dynamic light scattering, isothermal titration calorimetry, mass spectrometry, and computer modelling. Additionally, the modeling data showed that a molecule of D7H-Aβ, as well as isoD7-Aβ in combination with two Aβ molecules, renders a stable zinc-induced heterotrimer. …”
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9869
Permissive Modulation of Sphingosine-1-Phosphate-Enhanced Intracellular Calcium on BK<sub>Ca</sub> Channel of Chromaffin Cells
Published 2021-02-01“…Using multiple patch-clamp modes, Ca<sup>2+</sup> imaging, and computational modeling, we evaluated the effects of S1P on the Ca<sup>2+</sup>-activated K<sup>+</sup> currents (<i>I</i><sub>K(Ca)</sub>) in bovine adrenal chromaffin cells and in a pheochromocytoma cell line (PC12). …”
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Article -
9870
An IoT System and MODIS Images Enable Smart Environmental Management for Mekong Delta
Published 2023-07-01“…The system leverages telemetry data collected by IoT stations in combination with MODIS MOD09GA, MOD11A1, and MCD19A2 daily image products to develop computational models that calculate the values land surface temperature (LST), 2.5 and 10 (µm) particulate matter mass concentrations (PM2.5 and PM10) in areas without IoT stations. …”
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9871
Comparative genomics reveals the correlations of stress response genes and bacteriophages in developing antibiotic resistance of Staphylococcus saprophyticus
Published 2023-12-01“…The mecA gene could serve as a marker to infer cefoxitin and oxacillin resistance of S. saprophyticus, but the absence of this gene is not predictive of susceptibility. Utilizing computational modeling, we found several genes were associated with cefoxitin and oxacillin resistance in mecA− isolates, some of which have predicted functions in stress response and cell wall synthesis. …”
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9872
Factors Influencing Continued Wearable Device Use in Older Adult Populations: Quantitative Study
Published 2023-01-01“…The bespoke usability questionnaire determined that the 2 most important factors that influenced an intention to continue device use in an older adult cohort were device comfort (τ=0.34) and whether the device was fit for purpose (τ=0.34). A computational model providing an early identifier of intention to continue device use was developed using these 2 features. …”
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9873
4DVAR assimilation of GNSS zenith path delays and precipitable water into a numerical weather prediction model WRF
Published 2019-01-01“…Data assimilation combines atmospheric measurements with knowledge of atmospheric behavior as codified in computer models. With this approach, the “best” estimate of current conditions consistent with both information sources is produced. …”
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Article -
9874
Characterization of the Aeration and Hydrodynamics in Vertical-Wheel<sup>™</sup> Bioreactors
Published 2022-08-01“…Overall, this work provides new data regarding oxygen mass transfer and hydrodynamics in the Vertical-Wheel bioreactor, as well as new insights for air-water mass transfer modeling in systems with low interface deformation, and a computational model that can be used for further studies.…”
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Article -
9875
Discovery of putative inhibitors against main drivers of SARS-CoV-2 infection: Insight from quantum mechanical evaluation and molecular modeling
Published 2022-10-01“…In support of these approaches, we used a series of computational modeling approaches to develop therapeutic agents against COVID-19. …”
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9876
Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy
Published 2024-06-01“…Methods: We used a combination of echocardiography, transcriptomics, mass spectrometry-based untargeted metabolomics (GC-TOF, HILIC, CSH-QTOF), and computational modeling (CardioNet) to examine cardiac structural and metabolic remodeling at early disease stage (5 weeks of age) in R92W-TnT+/− and R403Q-MyHC+/− mutant mice. …”
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9877
CO2, Water and N2 Injection for Enhanced Oil Recovery with Spatial Arrangement of Fractures in Tight-Oil Reservoirs Using Huff-‘n-puff
Published 2019-03-01“…The equivalent core scale reservoir numerical models in depletion and huff-n-puff mode are then restored by numerical simulation with the Computer Modeling Group—Compositional & Unconventional Reservoir Simulator (CMG GEM). …”
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9878
From nonclinical research to clinical trials and patient-registries: challenges and opportunities in biomedical research
Published 2020“…In this article, we review the main stages and methods of biomedical research, from nonclinical studies with animal and computational models to randomized trials and clinical registries, focusing on their limitations and challenges, but also providing alternative solutions to overcome them. …”
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9879
Educação permanente à distância sobre a prevenção de úlcera por pressão [Distance continuing education on prevention of pressure ulcer]
Published 2016-06-01“…The program, hosted in a Moodle virtual learning environment, was developed and evaluated in the following stages: educational design, computational modeling, environment implementation, and ergonomic and pedagogical evaluation. …”
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9880
Internal two-phase flow induced vibrations: A review
Published 2022-12-01“…They are limited to simple cases involving simplified computational models. Experimental efforts for large multistructural components involve the initial use of prototypes and can prove to be costly for fully developed industrial-scale rigs. …”
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Article