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Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling
Published 2023-09-01“…Our results indicate that peptides with broad-spectrum anti-chemokine activity and therapeutic potential may be identified from evasins, and the pharmacophore characterised by phage display, saturation mutagenesis and computational modelling.…”
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1262
Participatory approach to introduce computational modeling at the undergraduate level, extending existing curricula and practices: Augmenting derivations
Published 2022-11-01“…Recent educational policies advocate a radical revision of science curricula and pedagogy, to support interdisciplinary practices, a distinguishing feature of contemporary science. Computational modeling (CM) is a core methodology of interdisciplinary science, as such models allow intertwining of data and theoretical perspectives from multiple domains, to address complex problems such as climate change and pandemics. …”
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A comparative analysis of 2D and 3D experimental data for the identification of the parameters of computational models
Published 2023-09-01“…Abstract Computational models are becoming an increasingly valuable tool in biomedical research. …”
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1265
Visual Blood, a 3D Animated Computer Model to Optimize the Interpretation of Blood Gas Analysis
Published 2023-02-01Get full text
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1266
Looking towards the future: patient-specific computational modeling to optimize outcomes for transcatheter mitral valve repair
Published 2023-04-01Subjects: Get full text
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1267
A computational model-based study on the feasibility of predicting post-splenectomy thrombosis using hemodynamic metrics
Published 2024-01-01Subjects: Get full text
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1268
Developing a 3-D computational model of neurons in the central amygdala to understand pharmacological targets for pain
Published 2023-05-01Subjects: Get full text
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1269
DEVELOPMENT OF COMPUTER MODEL AND INVESTIGATION OF HYDRAULIC OPERATIONAL MODES OF CIRCULATING SYSTEMS AT VAZ THERMAL POWER STATION
Published 2005-06-01“…Results of investigations of fluid levels in capacitances of cooling towers and in a forebay are shown on a computer model developed with the help of graph theory.…”
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1270
Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes.
Published 2012-01-01“…To further elucidate the underlying mechanisms, we have constructed a computational model of human β-cell glucose transport in health and in Type 2 diabetes, and present a systems analysis based on experimental results from human and animal studies. …”
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1271
Optimizing ultrasonic reactor operating variables using intelligent soft computing models for increased biodiesel production
Published 2023-09-01Subjects: Get full text
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1272
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Computational modeling of light processing in the habenula and dorsal raphe based on laser ablation of functionally-defined cells
Published 2024-04-01Subjects: Get full text
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1274
TorchDIVA: An extensible computational model of speech production built on an open-source machine learning library.
Published 2023-01-01“…The DIVA model is a computational model of speech motor control that combines a simulation of the brain regions responsible for speech production with a model of the human vocal tract. …”
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1275
ASRpro: A machine‐learning computational model for identifying proteins associated with multiple abiotic stress in plants
Published 2024-03-01“…In this work, we aimed to develop a computational model for identifying genes responsive to six abiotic stresses: cold, drought, heat, light, oxidative, and salt. …”
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Computational modeling of ventricular-ventricular interactions suggest a role in clinical conditions involving heart failure
Published 2023-09-01Subjects: Get full text
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1279
Exploring the steps of learning: computational modeling of initiatory-actions among individuals with attention-deficit/hyperactivity disorder
Published 2024-01-01“…Specifically, 54 participants (28 ADHD, 26 controls) completed a value-based reinforcement-learning task that allowed us to estimate internal action values for each trial and stage using computational modeling. We found attenuated sensitivity to action values in ADHD compared to controls, both in choice and reaction-time variability estimates. …”
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P124 Impact of Tapering on Arterial Blood Pressure Using a One-dimensional Computational Model
Published 2020-02-01Get full text
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