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Coupling Genotyping and Computational Modeling in Prediction of Anti-epileptic Drugs that cause Stevens Johnson Syndrome and Toxic Epidermal Necrolysis for Carrier of HLA-B*15:02
Published 2016-03-01“…The patients were genotyped by AS-PCR. Computational modeling of the HLA-B*15:02 followed by docking studies were performed to screen 26 AEDs that may induce ADR among HLA-B*15:02 carriers. …”
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BBB-PEP-prediction: improved computational model for identification of blood–brain barrier peptides using blending position relative composition specific features and ensemble modeling
Published 2023-11-01“…In this study, we proposed an improved intelligent computational model BBB-PEP-Prediction for identification of BBB peptides. …”
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A computational model of visual marking using an inter-connected network of spiking neurons: the spiking search over time and space model (sSoTS).
Published 2006“…In this paper we present, for the first time, an explicit computational model of visual marking using biologically plausible activation functions. …”
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Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus.
Published 2014-05-01“…Here we adapted an existing computational model of the dentate gyrus by replacing the reduced granule cell models with morphologically detailed models coming from three-dimensional reconstructions of mature cells. …”
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Synergistic Effect of Combination Interventions for Methicillin-Resistant <i>Staphylococcus aureus</i> Transmission Control in Nursing Homes: A Computation Modelling Evaluation with Heterogeneous Contact Mixing
Published 2021-02-01“…Nursing homes are considered as major reservoirs for MRSA colonization, with considerable high levels of colonization prevalence. We employed a computation model to evaluate effects of three intervention scenarios on MRSA colonization prevalence rate in nursing homes. …”
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Altered synaptic plasticity at hippocampal CA1–CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models
Published 2023-12-01“…The goal of the present study is to build computational models that incorporate the effect of AD-related peptides on CA1 pyramidal neuron and hippocampal synaptic plasticity under the AD conditions and investigate the potential pharmacological treatments that could normalize hippocampal synaptic plasticity and learning in AD. …”
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<i>DETECT-LC</i>: A 3D Deep Learning and Textural Radiomics Computational Model for Lung Cancer Staging and Tumor Phenotyping Based on Computed Tomography Volumes
Published 2022-06-01“…In this study, a multistage neurobased computational model is proposed, <i>DETECT-LC</i> learning. …”
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