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Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug <i>Rhynocoris iracundus</i>
Published 2021-07-01“…We identified neurotoxic Ptu1, an inhibitory cystin knot (ICK) toxin homologous to ω-conotoxins from cone snails, cytolytic redulysins homologous to trialysins from hematophagous kissing bugs, and pore-forming hemolysins. …”
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322
Marine Origin Ligands of Nicotinic Receptors: Low Molecular Compounds, Peptides and Proteins for Fundamental Research and Practical Applications
Published 2022-01-01“…The most sophisticated instruments to distinguish muscle from neuronal nAChRs, and especially distinct subtypes within the latter, are α-conotoxins. Such information is crucial for fundamental studies on the nAChR revealing the properties of their orthosteric and allosteric binding sites and mechanisms of the channel opening and closure. …”
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323
DNA barcoding of seven cone snail species from Red Sea coast of Egypt
Published 2021-03-01“…The production of bioactive molecules (known as conopeptides or conotoxins) marks the Conus as an utmost promising animal source for medicinal applications. …”
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324
Fifty Years of Animal Toxin Research at the Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
Published 2023-09-01“…In marine animals, versatile toxins in terms of structure and molecular targets were discovered, and careful work on α-conotoxins differing in specificity for individual nAChR subtypes gave information about their binding sites.…”
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325
Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients [version 2; peer review: 2 approved]
Published 2021-10-01“…Results: Toxin-like peptides, almost identical to toxic components of venoms from animals, like conotoxins, phospholipases, phosphodiesterases, zinc metal proteinases, and bradykinins, were identified in samples from COVID-19 patients, but not in control samples. …”
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