A novel proline-rich M-superfamily conotoxin that can simultaneously affect sodium, potassium and calcium currents by Manyi Yang, Yubin Li, Longfei Liu, Maojun Zhou

Subjects: “…Conotoxin…”
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Isolation and structural identification of a new T1-conotoxin with unique disulfide connectivities derived from Conus bandanus by Nguyen Bao, Jean-Pière Lecaer, Ngo Dang Nghia, Phan Thi Khanh Vinh

Subjects: “…T1-subfamily conotoxin…”
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Selecting Potential Neuronal Drug Leads from Conotoxins of Various Venomous Marine Cone Snails in Bali, Indonesia by Anak A. R. Sudewi, Ni M. Susilawathi, Bayu K. Mahardika, Agung N. Mahendra, Made Pharmawati, Mark A. Phuong, Gusti N. Mahardika

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Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1 by Aaron G. Poth, Francis C.K. Chiu, Sofie Stalmans, Brett R. Hamilton, Yen-Hua Huang, David M. Shackleford, Rahul Patil, Thao T. Le, Meng-Wei Kan, Thomas Durek, Evelien Wynendaele, Bart De Spiegeleer, Andrew K. Powell, Deon J. Venter, Richard J. Clark, Susan A. Charman, David J. Craik

Subjects: “…conotoxin…”
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N-type calcium channel blockers: a new approach towards the treatment of chronic neuropathic pain by Shikha Choudhary, Raminderjit Kaur, Aafrin Waziri, Arun Garg, Renu Kadian, Md Sabir Alam

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O1-conotoxin Tx6.7 cloned from the genomic DNA of Conus textile that inhibits calcium currents by Maojun Zhou, Manyi Yang, Huiling Wen, Shun Xu, Cuifang Han, Yun Wu

Subjects: “…conotoxin…”
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Molecular determinants of μ-conotoxin KIIIA interaction with the human voltage-gated sodium channel NaV1.7 by Ian H. Kimball, Phuong T. Nguyen, Baldomero M. Olivera, Jon T. Sack, Jon T. Sack, Vladimir Yarov-Yarovoy, Vladimir Yarov-Yarovoy

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Synthesis of Cystine-Stabilised Dicarba Conotoxin EpI: Ring-Closing Metathesis of Sidechain Deprotected, Sulfide-Rich Sequences by Amy L. Thomson, Andrea J. Robinson, Alessia Belgi

“…The chemistry is exemplified using α-conotoxin EpI, a native bicyclic disulfide-containing sequence isolated from the marine conesnail <i>Conus episcopatus</i>. …”
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µ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype Na_V1.7 by Kirsten L. McMahon, Hue N. T. Tran, Jennifer R. Deuis, David J. Craik, Irina Vetter, Christina I. Schroeder

Subjects: “…µ-conotoxins…”
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Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail by Bingmiao Gao, Chao Peng, Bo Lin, Qin Chen, Junqing Zhang, Qiong Shi

Subjects: “…conotoxin…”
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Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K by Domenico Di Curzio, Mamneet Gurm, Matthew Turnbull, Marie-Josée Nadeau, Breanna Meek, Julia D. Rempel, Samuel Fineblit, Michael Jonasson, Sherry Hebert, Jennifer Ferguson-Parry, Renée N. Douville

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The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site by Alican Gulsevin, Roger L. Papke, Clare Stokes, Hue N. T. Tran, Aihua H. Jin, Irina Vetter, Jens Meiler

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Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus by Julien Giribaldi, David Wilson, Annette Nicke, Yamina El Hamdaoui, Guillaume Laconde, Adèle Faucherre, Hamid Moha Ou Maati, Norelle L. Daly, Christine Enjalbal, Sébastien Dutertre

Subjects: “…conotoxins…”
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Effect of Methionine Oxidation and Substitution of α-Conotoxin TxID on α3β4 Nicotinic Acetylcholine Receptor by Jie Ren, Rui Li, Jiong Ning, Xiaopeng Zhu, Dongting Zhangsun, Yong Wu, Sulan Luo

Subjects: “…α-Conotoxin TxID…”
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Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment by Xiaoyu Zhu, Mei Yuan, Huanbai Wang, Dongting Zhangsun, Gang Yu, Jinjing Che, Sulan Luo

Subjects: “…αO-conotoxin GeXIVA[1,2]…”
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Molecular docking study on the α3β2 neuronal nicotinic acetylcholine receptor complexed with α-Conotoxin GIC by Chewook Lee, Si-Hyung Lee, Do-Hyoung Kim, Kyou-Hoon Han

Subjects: “…α-Conotoxin GIC…”
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Characterisation of Elevenin-Vc1 from the Venom of <i>Conus victoriae</i>: A Structural Analogue of α-Conotoxins by Bankala Krishnarjuna, Punnepalli Sunanda, Jeffrey Seow, Han-Shen Tae, Samuel D. Robinson, Alessia Belgi, Andrea J. Robinson, Helena Safavi-Hemami, David J. Adams, Raymond S. Norton

“…The elevenin-Vc1 structural fold is similar to that of α-conotoxins such as α-RgIA and α-ImI, which are also found in the venoms of cone snails and are antagonists at specific subtypes of nicotinic acetylcholine receptors (nAChRs). …”
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Identification of Novel Conotoxin Precursors from the Cone Snail <i>Conus spurius</i> by High-Throughput RNA Sequencing by Roberto Zamora-Bustillos, Mario Alberto Martínez-Núñez, Manuel B. Aguilar, Reyna Cristina Collí-Dula, Diego Alfredo Brito-Domínguez

“…To our knowledge, this report is the first to use high-throughput RNA sequencing for the study of the diversity of <i>C. spurius</i> conotoxins.…”
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Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations by Dana Katz, Michael A. DiMattia, Dan Sindhikara, Hubert Li, Nikita Abraham, Abba E. Leffler

Subjects: “…conotoxin…”
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A New Member of Gamma-Conotoxin Family Isolated from Conus princeps Displays a Novel Molecular Target by Johanna Bernáldez, Samanta Jiménez, Luis Javier González, Jesús Noda Ferro, Enrique Soto, Emilio Salceda, Daniela Chávez, Manuel B. Aguilar, Alexei Licea-Navarro

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