Showing 121 - 140 results of 325 for search '"conotoxin"', query time: 0.12s Refine Results
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    A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3. by Celeste M Hackney, Paula Flórez Salcedo, Emilie Mueller, Thomas Lund Koch, Lau D Kjelgaard, Maren Watkins, Linda G Zachariassen, Pernille Sønderby Tuelung, Jeffrey R McArthur, David J Adams, Anders S Kristensen, Baldomero Olivera, Rocio K Finol-Urdaneta, Helena Safavi-Hemami, Jens Preben Morth, Lars Ellgaard

    Published 2023-08-01
    “…The venoms of marine cone snails constitute a particularly rich source of peptide toxins, known as conotoxins. Here, we identify the sequence of an unusually large conotoxin, Mu8.1, which defines a new class of conotoxins evolutionarily related to the well-known con-ikot-ikots and 2 additional conotoxin classes not previously described. …”
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    Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations by Xiaoxiao Xu, Jiazhen Liang, Zheyu Zhang, Tao Jiang, Rilei Yu

    Published 2019-05-01
    “…Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are involved in fast synaptic transmission and mediated physiological activities in the nervous system. α-Conotoxin ImI exhibits subtype-specific blockade towards homomeric α7 and α9 receptors. …”
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    Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. by Rilei Yu, David J Craik, Quentin Kaas

    Published 2011-03-01
    “…α-Conotoxins potently inhibit isoforms of nicotinic acetylcholine receptors (nAChRs), which are essential for neuronal and neuromuscular transmission. …”
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    Simulation of folding pathway studies of TRP-cage miniprotein, Amyloid A4 peptide and α-conotoxin RgIa peptide by Mohamed Tap, Fatahiya

    Published 2013
    “…Amyloid A4 peptide (350ns) and a-conotoxin (800ns) were simulated in implicit solvent, while the simulation for Trp-cage (150ns) and a-conotoxin (200ns) were performed in explicit solvent method. …”
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    Simulation of folding pathway studies of trp-cage miniprotein, amyloid A4 peptide, and a-conotoxin RgIA peptide by Mohamed Tap, Fatahiya

    Published 2013
    “…Amyloid A4 peptide (350ns) and a-conotoxin (800ns) were simulated in implicit solvent, while the simulation for Trp-cage (150ns) and a-conotoxin (200ns) were performed in explicit solvent method. …”
    Thesis
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