Visual closed dumbbell-mediated isothermal amplification (CDA) for on-site detection of Rickettsia raoultii. by Zheng Gui, Hao Cai, Lin Wu, Qing Miao, Jing Feng Yu, Ting Cai, Rui Mao

“…In this study, a R. raoultii diagnosis method by closed dumbbell-mediated isothermal amplification (R-CDA) assay targeting a conserved sequence of the outer membrane protein A (OmpA) gene with high sensitivity and specificity was developed. …”
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The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids by Ngai John, Alioto Tyler S

“…Interestingly, an analysis of sequence conservation and selective pressure in the zebrafish receptors revealed the retention of a conserved sequence motif previously shown to be required for ligand binding in other amino acid receptors.…”
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Comparison of ESTs from juvenile and adult phases of the giant unicellular green alga <it>Acetabularia acetabulum</it> by Grotewold Erich, Schwarz-Sommer Zsuzsanna, Hernandez J Marcela, Wilkinson Mark D, Henry Isabelle M, Mandoli Dina F

“…Comparison of our EST sequences against publicly available sequence databases indicates that ESTs from the adult and the juvenile libraries partition into different functional classes. Three conserved sequence elements were common to several of the ESTs and were also found within the genomic sequence of the carbonic anhydrase1 gene from <it>A. acetabulum</it>. …”
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The crystal structure of XdpB, the bacterial old yellow enzyme, in an FMN-free form. by Jiří Zahradník, Petr Kolenko, Andrea Palyzová, Jiří Černý, Lucie Kolářová, Eva Kyslíková, Helena Marešová, Michal Grulich, Jaroslav Nunvar, Miroslav Šulc, Pavel Kyslík, Bohdan Schneider

“…This subgroup is widespread among G-bacteria and can be recognized by the conserved sequence GxxDYP in proximity of the C termini. …”
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Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex. by Mohaddeseh Peyro, Mohammad Soheilypour, Ali Ghavami, Mohammad R K Mofrad

“…In our recent bioinformatics study, we showed that FG Nups have some evolutionarily conserved sequence-based features that might govern their physical behavior inside the NPC. …”
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Viral proteins acquired from a host converge to simplified domain architectures. by Nadav Rappoport, Michal Linial

“…Only a small number of them represent viruses that hijacked host sequences. The low-conservation sequence analysis utilizes the Pfam family collection. …”
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Ultraconserved Non-coding DNA Within Diptera and Hymenoptera by Thomas Brody, Amarendra Yavatkar, Alexander Kuzin, Ward F. Odenwald

“…We compared non-coding sequences found within and flanking Drosophila developmental genes to homologous sequences in Ceratitis capitata and Musca domestica. Many of the conserved sequence blocks (CSBs) that constitute Drosophila cis-regulatory DNA, recognized by EvoPrinter alignment protocols, are also conserved in Ceratitis and Musca. …”
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Alternative Oxidase Transcription Factors AOD2 and AOD5 of Neurospora crassa Control the Expression of Genes Involved in Energy Production and Metabolism by Zhigang Qi, Kristina M. Smith, Erin L. Bredeweg, Natasa Bosnjak, Michael Freitag, Frank E. Nargang

“…The most striking of these was a conserved sequence that bound large amounts of AOD2 but little AOD5. …”
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fimH gene cloning, of Escherichia coli uropathogen and examination of its subsequence diversity by Samaneh Ostad Mohammadi, Mohammad Hasan Shirazi, Jalil Fallah Mehrabadi, Mohammad Reza Pourmand, Faezeh Hamidieh, Hedroosha Molla Agha Mirzaie, Davood Afshar

“…Conclusion: N terminal domain of fimH gene is a conserved sequence among clinical isolates and it could be used for designing a vaccine against urinary tract infection.…”
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Targeted disruption of the intracellular domain of receptor FgfrL1 in mice. by Gilles Bluteau, Lei Zhuang, Ruth Amann, Beat Trueb

“…To investigate the function of the intracellular domain of FgfrL1, we have prepared genetically modified mice that lack the three conserved sequence motifs, but instead contain a GFP cassette (FgfrL1ΔC-GFP). …”
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The Disordered Dehydrin and Its Role in Plant Protection: A Biochemical Perspective by Margaret A. Smith, Steffen P. Graether

“…Dehydrins are intrinsically disordered proteins composed of several well conserved sequence motifs known as the Y-, S-, F-, and K-segments, the latter of which is a defining feature of all dehydrins. …”
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Efficient Detection of Novel Nuclear Markers for Brassicaceae by Transcriptome Sequencing. by Reinhold Stockenhuber, Stefan Zoller, Rie Shimizu-Inatsugi, Felix Gugerli, Kentaro K Shimizu, Alex Widmer, Martin C Fischer

“…We first obtained and mapped NGS transcriptome sequencing reads from two of the distantly related Brassicaceae species, Cardamine hirsuta and Arabis alpina, onto the Arabidopsis thaliana reference genome, and then identified short conserved sequence motifs among the three species bioinformatically. …”
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The cell cycle regulated transcriptome of Trypanosoma brucei. by Stuart K Archer, Diana Inchaustegui, Rafael Queiroz, Christine Clayton

“…Furthermore, we found evidence for cell-cycle regulation of a flagellar protein regulon with a highly conserved sequence motif, bearing similarity to consensus PUF-protein binding motifs. …”
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Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis. by Jeffrey D Nanson, Jade K Forwood

“…FabG enzymes are members of the short-chain alcohol dehydrogenase/reductase (SDR) family, and like other SDRs, exhibit highly conserved secondary and tertiary structures, and contain a number of conserved sequence motifs. Here we describe the crystal structures of FabG from Yersinia pestis (YpFabG), the causative agent of bubonic, pneumonic, and septicaemic plague, and three human pandemics. …”
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Molecular Cloning, Sequence Identification and Tissue Expression Profile of Three Novel Sheep (Ovis aries) Genes - BCKDHA, NAGA and HEXA by G. Y LIU, S.Z GAO

“…The complete coding sequences of three sheep genes- BCKDHA, NAGA and HEXA were amplified using the reverse transcriptase polymerase chain reaction (RT-PCR), based on the conserved sequence information of the mouse or other mammals. …”
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Patterns of Sequence and Expression Diversification Associate Members of the PADRE Gene Family With Response to Fungal Pathogens by Marie Didelon, Mehdi Khafif, Laurence Godiard, Adelin Barbacci, Sylvain Raffaele

“…PADRE N-terminus harbors conserved sequence motifs, while its C-terminus includes an intrinsically disordered region with multiple phosphorylation sites. …”
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Host-pathogen o-methyltransferase similarity and its specific presence in highly virulent strains of Francisella tularensis suggests molecular mimicry. by Mia D Champion

“…Related protein families were identified in several host species as well as species of pathogenic bacteria that are otherwise very distant phylogenetically from Francisella, including species of Mycobacterium. A conserved sequence motif profile is present in the mammalian host and pathogen protein sequences, and sites of non-synonymous variation conserved in Francisella subspecies specific o-methyltransferases map proximally to the predicted active site of the orthologous human protein structure. …”
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Mutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points. by Anne Norris, Collin T McManus, Simon Wang, Ruochen Ying, Barth D Grant

“…To better understand the mechanism of RME-8 function we performed a new phylogenetic analysis of RME-8 and identified new conserved sequence features. In a complementary approach, we performed structure-function analysis that identified the C-terminus as important for microdomain localization and likely substrate binding, while N-terminal sequences beyond the known single N-terminal PH-like domain are important for endosome recruitment. …”
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Patterns in the sequence context of protein disulfide bonds by Eklund, Aron Charles, 1974-

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Mutation analysis of glial cell line-derived neurotrophic factor (GDNF), a ligand for the RET/GDNF receptor alpha complex, in sporadic phaeochromocytomas. by Dahia, P, Toledo, S, Mulligan, L, Maher, E, Grossman, AB, Eng, C

“…Among these samples, only a conservative sequence variant was detected in exon 2 of GDNF. …”