Tipping the scales: Immunotherapeutic strategies that disrupt immunosuppression and promote immune activation by Ginette S. Santiago-Sánchez, James W. Hodge, Kellsye P. Fabian

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NK cells blur the frontier between innate and acquired immunity. by Ennio eCarbone, Ennio eCarbone, Giuseppe eTerrazzano, Giuseppe eTerrazzano

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Development and characterization of a novel human CD137 agonistic antibody with anti‐tumor activity and a good safety profile in non‐human primates by Yingying Gao, Teddy Yang, Hu Liu, Ningning Song, Chaohui Dai, Yu Ding

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Combining CSPG4-CAR and CD20-CCR for treatment of metastatic melanoma by Karin Teppert, Nora Winter, Vera Herbel, Caroline Brandes, Simon Lennartz, Fabian Engert, Andrew Kaiser, Thomas Schaser, Dominik Lock

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PD-L1 chimeric costimulatory receptor improves the efficacy of CAR-T cells for PD-L1-positive solid tumors and reduces toxicity in vivo by Qibin Liao, Yunyu Mao, Huan He, Xiangqing Ding, Xiaoyan Zhang, Jianqing Xu

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In vivo validation of the switch antibody concept: SPECT/CT imaging of the anti-CD137 switch antibody Sta-MB shows high uptake in tumors but low uptake in normal organs in human CD... by Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Yoshinori Narita, Kenji Taniguchi, Takayuki Nemoto, Fumihisa Isomura, Norihiro Awaya, Mika Kamata-Sakurai, Tatsuya Higashi

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The homodimer interfaces of costimulatory receptors B7 and CD28 control their engagement and pro-inflammatory signaling by Andrey Popugailo, Ziv Rotfogel, Michal Levy, Orli Turgeman, Dalia Hillman, Revital Levy, Gila Arad, Tomer Shpilka, Raymond Kaempfer

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Targeting CD137 (4-1BB) towards improved safety and efficacy for cancer immunotherapy by Guizhong Liu, Guizhong Liu, Peter Luo, Peter Luo

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