Molecular determinants of TRPM8 function: key clues for a cool modulation by María Pertusa, María Pertusa, María Pertusa, Jocelyn Solorza, Jocelyn Solorza, Rodolfo Madrid, Rodolfo Madrid, Rodolfo Madrid

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Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein by Shuyuan Zhang, Wenxv Jia, Wenxv Jia, Jianwei Zeng, Mingxi Li, Mingxi Li, Ziyi Wang, Haixia Zhou, Linqi Zhang, Linqi Zhang, Xinquan Wang

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Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates by Xue Fei, Tristan A Bell, Sarah R Barkow, Tania A Baker, Robert T Sauer

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P-Loop Channels: Experimental Structures, and Physics-Based and Neural Networks-Based Models by Denis B. Tikhonov, Boris S. Zhorov

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Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA‐Dependent Transcription Activation by Min Hao, Fuzhou Ye, Milija Jovanovic, Ioly Kotta‐Loizou, Qingqing Xu, Xiaohua Qin, Martin Buck, Xiaodong Zhang, Minggui Wang

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Chromogranin B (CHGB) is dimorphic and responsible for dominant anion channels delivered to cell surface via regulated secretion by Gaya P. Yadav, Gaya P. Yadav, Gaya P. Yadav, Haiyuan Wang, Joke Ouwendijk, Stephen Cross, Qiaochu Wang, Feng Qin, Paul Verkade, Michael X. Zhu, Qiu-Xing Jiang, Qiu-Xing Jiang, Qiu-Xing Jiang, Qiu-Xing Jiang

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Emerging structures and dynamic mechanisms of γ-secretase for Alzheimer’s disease by Yinglong Miao, Michael S. Wolfe

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The Origin Recognition Complex: From Origin Selection to Replication Licensing in Yeast and Humans by Bik-Kwoon Tye, Yuanliang Zhai

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Neuropathology and molecular diagnosis of Synucleinopathies by Shunsuke Koga, Hiroaki Sekiya, Naveen Kondru, Owen A. Ross, Dennis W. Dickson

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Structural Insight into the Mechanism of <i>N</i>-Linked Glycosylation by Oligosaccharyltransferase by Smita Mohanty, Bharat P Chaudhary, David Zoetewey

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Cryo-EM of α-tubulin isotype-containing microtubules revealed a contracted structure of α4A/β2A microtubules by Diao Lei, Zheng Wei, Zhao Qiaoyu, Liu Mingyi, Fu Zhenglin, Zhang Xu, Bao Lan, Cong Yao

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Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter by Yan Wang, Yan Han, Ji She, Nam X Nguyen, Vamsi K Mootha, Xiao-chen Bai, Youxing Jiang

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A pan-orthoebolavirus neutralizing antibody encoded by mRNA effectively prevents virus infection by Pengfei Fan, Bingjie Sun, Zixuan Liu, Ting Fang, Yi Ren, Xiaofan Zhao, Zhenwei Song, Yilong Yang, Jianmin Li, Changming Yu, Wei Chen

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Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1 by Demeng Sun, Sanling Liu, Siyu Li, Mengge Zhang, Fan Yang, Ming Wen, Pan Shi, Tao Wang, Man Pan, Shenghai Chang, Xing Zhang, Longhua Zhang, Changlin Tian, Lei Liu

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CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3 by Vineeta Kaushik, Luca Gessa, Nelam Kumar, Matyáš Pinkas, Mariusz Czarnocki-Cieciura, Krzysztof Palczewski, Jiří Nováček, Humberto Fernandes

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Structural Pharmacology of TRPV4 Antagonists by Junping Fan, Chang Guo, Daohong Liao, Han Ke, Jing Lei, Wenjun Xie, Yuliang Tang, Makoto Tominaga, Zhuo Huang, Xiaoguang Lei

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Vaccine Potency and Structure of Yeast-Produced Polio Type 2 Stabilized Virus-like Particles by Qin Hong, Shuxia Wang, Xiaoli Wang, Wenyu Han, Tian Chen, Yan Liu, Fei Cheng, Song Qin, Shengtao Zhao, Qingwei Liu, Yao Cong, Zhong Huang

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Cryo‐EM structure of fission yeast tetrameric α‐mannosidase Ams1 by Jianxiu Zhang, Ying‐Ying Wang, Li‐Lin Du, Keqiong Ye

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Structural basis of a microbial trimethylamine transporter by Chao Gao, Hai-Tao Ding, Kang Li, Hai-Yan Cao, Ning Wang, Zeng-Tian Gu, Qing Wang, Mei-Ling Sun, Xiu-Lan Chen, Yin Chen, Yu-Zhong Zhang, Hui-Hui Fu, Chun-Yang Li

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Structural basis of properties, mechanisms, and channelopathy of cyclic nucleotide-gated channels by Zhengshan Hu, Jian Yang

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