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1041
Chronic Inflammation in the Epidermis: A Mathematical Model
Published 2016-09-01“…We develop mathematical models (M1 and M2 models) for the inflammation process using ordinary differential equations and delay differential equations. In this paper, we study microbial community dynamics via transcription factors, protease and extracellular cytokines. …”
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1042
Block hybrid methods for numerical treatment of differential equations with applications
Published 2016“…The one-point block hybrid methods are then implemented for numerical solution of first order delay differential equations (DDEs). The Q-stability of the methods is investigated. …”
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Thesis -
1043
Scientific Machine Learning for Dynamical Systems: Theory and Applications to Fluid Flow and Ocean Ecosystem Modeling
Published 2023“…Next, motivated by the presence of inherent delays in real-world systems and the Mori-Zwanzig formulation, we develop a novel delay-differential-equations-based deep learning framework to learn time-delayed closure parameterizations for missing dynamics. …”
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Thesis -
1044
Generalized neural closure models with interpretability
Published 2024“…In the present study, we simultaneously address all these challenges by developing the novel and versatile methodology of unified neural partial delay differential equations. We augment existing/low-fidelity dynamical models directly in their partial differential equation (PDE) forms with both Markovian and non-Markovian neural network (NN) closure parameterizations. …”
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1045
A general modeling framework for quantitative tracking, accurate prediction of ICU, and assessing vaccination for COVID-19 in Chile
Published 2023-03-01“…Consequently, this article aims to develop a general framework consisting of epidemiological modeling and a practical identifiability approach to assess combined vaccination and non-pharmaceutical intervention (NPI) strategies for the dynamics of any transmissible disease.Materials and methodsEpidemiological modeling of the present work relies on delay differential equations describing time variation and transitions between suitable compartments. …”
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1046
The role of primary and secondary delays in the effective resonance frequency of acoustically interacting microbubbles
Published 2022-05-01“…Inclusion of the secondary delays modifies the class of the differential equations governing the oscillations of interacting MBs in a cluster from ordinary differential equations to neutral delay differential equations. Previous work has not considered the all the delays associated with the bubble distances when modeling the interactions between bubbles. …”
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1047
Modeling the dynamics of glucose, insulin, and free fatty acids with time delay: The impact of bariatric surgery on type 2 diabetes mellitus
Published 2019-06-01“…The dynamics of the nonlinear interactions that involve glucose, insulin, and FFA are modeled by incorporating a fixed-time delay with the corresponding delay-differential equations being studied numerically. The results of computational studies, that is, extensive simulations, are compared to the known minimal ordinary differential equations model. …”
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1048
Investigating small non-coding RNA regulating the hallmarks of cancer
Published 2018“…By analysing a system of delay differential equations in the deterministic and stochastic settings, I uncovered the range of potential dynamics that this feedback loop could exhibit. …”
Thesis -
1049
Non-Linear Dynamical Analysis of EEG Time Series Distinguishes Patients with Parkinson’s Disease from Healthy Individuals
Published 2013-12-01“…The pathophysiology of Parkinson’s disease (PD) is known to involve altered patterns of neuronal firing and synchronization in cortical-basal ganglia circuits. We used delay differential equations (DDE) as non-linear time-domain classification tools to analyze electroencephalographic (EEG) recordings from PD patients on and off dopaminergic therapy and healthy individuals. …”
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1050
Stochastic model of cancer growth with the effect of glycosaminoglycans (GAGs) as anticancer therapeutics
Published 2019“…It is necessary to model the untreated cancer growth process via stochastic delay differential equations (SDDEs). Nowadays, cancers are traditionally treated with surgery, chemotherapy, and radiotherapy. …”
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Thesis -
1051
Predicting and Reconstructing Aerosol–Cloud–Precipitation Interactions with Physics-Informed Neural Networks
Published 2023-12-01“…We demonstrate the PINN’s ability to reconstruct the past with limited data for a dynamic system with nonlinear delayed differential equations, such as the Koren–Feingold model, which remains underexplored in the literature. …”
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1052
Bifurcation analysis of multistability and hysteresis in a model of HIV infection
Published 2023-12-01“…To this end, original computational methods of bifurcation analysis of mathematical models formulated with systems of ordinary differential equations and delay differential equations are used. The macrophage activation rate constant is considered as a bifurcation parameter. …”
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1053
New Oscillation Theorems for Second-Order Differential Equations with Canonical and Non-Canonical Operator via Riccati Transformation
Published 2021-05-01“…In this work, we prove some new oscillation theorems for second-order neutral delay differential equations of the form <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mo>(</mo><mi>a</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mrow><mo>(</mo><msup><mrow><mo>(</mo><mi>v</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>+</mo><mi>b</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mi>v</mi><mrow><mo>(</mo><mi>ϑ</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>)</mo></mrow><mo>)</mo></mrow><mo>′</mo></msup><mo>)</mo></mrow><mo>)</mo></mrow><mo>′</mo></msup><mo>+</mo><mi>c</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><msub><mi>G</mi><mn>1</mn></msub><mrow><mo>(</mo><mi>v</mi><mrow><mo>(</mo><mi>κ</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>)</mo></mrow><mo>)</mo></mrow><mo>+</mo><mi>d</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><msub><mi>G</mi><mn>2</mn></msub><mrow><mo>(</mo><mi>v</mi><mrow><mo>(</mo><mi>ς</mi><mrow><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow><mo>)</mo></mrow><mo>)</mo></mrow><mo>=</mo><mn>0</mn></mrow></semantics></math></inline-formula> under canonical and non-canonical operators, that is, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msubsup><mo>∫</mo><mrow><msub><mi>ξ</mi><mn>0</mn></msub></mrow><mo>∞</mo></msubsup><mfrac><mrow><mi>d</mi><mi>ξ</mi></mrow><mrow><mi>a</mi><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow></mfrac><mo>=</mo><mo>∞</mo></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msubsup><mo>∫</mo><mrow><msub><mi>ξ</mi><mn>0</mn></msub></mrow><mo>∞</mo></msubsup><mfrac><mrow><mi>d</mi><mi>ξ</mi></mrow><mrow><mi>a</mi><mo>(</mo><mi>ξ</mi><mo>)</mo></mrow></mfrac><mo><</mo><mo>∞</mo></mrow></semantics></math></inline-formula>. …”
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1054
Oscillation and Asymptotic Properties of Differential Equations of Third-Order
Published 2021-08-01“…The main purpose of this study is aimed at developing new criteria of the iterative nature to test the asymptotic and oscillation of nonlinear neutral delay differential equations of third order with noncanonical operator <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mo>(</mo><mi>a</mi><mrow><mo>(</mo><mi>ι</mi><mo>)</mo></mrow><msup><mrow><mo>[</mo><mo>(</mo><mi>b</mi><mrow><mo>(</mo><mi>ι</mi><mo>)</mo></mrow><msup><mfenced separators="" open="[" close="]"><mi>x</mi><mo>(</mo><mi>ι</mi><mo>)</mo><mo>+</mo><mi>p</mi><mo>(</mo><mi>ι</mi><mo>)</mo><mi>x</mi><mo>(</mo><mi>ι</mi><mo>−</mo><mi>τ</mi><mo>)</mo></mfenced><mo>′</mo></msup><mo>)</mo></mrow><mo>′</mo></msup><mo>]</mo></mrow><mi>β</mi></msup><msup><mrow><mo>)</mo></mrow><mo>′</mo></msup></mrow></semantics></math></inline-formula><inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>+</mo><msubsup><mo>∫</mo><mrow><mi>c</mi></mrow><mi>d</mi></msubsup><mi>q</mi><mrow><mo>(</mo><mi>ι</mi><mo>,</mo><mi>μ</mi><mo>)</mo></mrow><msup><mi>x</mi><mi>β</mi></msup><mrow><mo>(</mo><mi>σ</mi><mrow><mo>(</mo><mi>ι</mi><mo>,</mo><mi>μ</mi><mo>)</mo></mrow><mo>)</mo></mrow><mspace width="0.166667em"></mspace><mi>d</mi><mi>μ</mi><mo>=</mo><mn>0</mn><mo>,</mo></mrow></semantics></math></inline-formula> where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>ι</mi><mo>≥</mo><msub><mi>ι</mi><mn>0</mn></msub></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>w</mi><mo>(</mo><mi>ι</mi><mo>)</mo><mo>:</mo><mo>=</mo><mi>x</mi><mo>(</mo><mi>ι</mi><mo>)</mo><mo>+</mo><mi>p</mi><mo>(</mo><mi>ι</mi><mo>)</mo><mi>x</mi><mo>(</mo><mi>ι</mi><mo>−</mo><mi>τ</mi><mo>)</mo></mrow></semantics></math></inline-formula>. …”
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1055
Exploring efficient: numerical methods for differential equations
Published 2016“…In this research, it is proven that trigonometrically-fitting the hybrid methods and applying them to solve oscillatory delay differential equations result in better numerical results. …”
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Inaugural Lecture