Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism by Pujadas Liwag, Emily M., Wei, Xiaolong, Acosta, Nicolas, Carter, Lucas M., Yang, Jiekun, Almassalha, Luay M., Jain, Surbhi, Daneshkhah, Ali, Rao, Suhas S. P., Seker-Polat, Fidan, MacQuarrie, Kyle L., Ibarra, Joe, Agrawal, Vasundhara, Aiden, Erez Lieberman, Kanemaki, Masato T., Backman, Vadim, Adli, Mazhar

“…Lamin B1 and lamin B2 depletion minimally alters higher-order chromatin folding but disrupts cell morphology, significantly increases chromatin mobility, redistributes both constitutive and facultative heterochromatin, and induces differential gene expression both within and near lamin-associated domain (LAD) boundaries. …”
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Focused array analysis of diabetic skin wound. by Ling, Wei Yin.

“…To understand the interplay among these players behind angiogenesis and discover possible therapeutic targets, a focused array approach employing real-time quantitative PCR technique was used to unravel the differential gene molecular profiles in the healing of chronic diabetic mice wounds compared to that of normal wounds. …”
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Loss of NnT increases expression of oxidative phosphorylation complexes in C57BL/6J hearts by Williams, Jack L., Hall, Charlotte L., Meimaridou, Eirini, Metherell, Louise A.

“…We saw enrichment of oxidative phosphorylation genes in the C57BL/B6J in the heart and adrenal, possibly indicative of an evolved response in this substrain to loss of Nnt. However, differential gene expression was mainly driven by mouse background with some changes seen in all three tissues, perhaps reflecting underlying genetic differences between the C57BL/B6J and -6N substrains.…”
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Using an aerosol human BCG infection model to define the early immune response in the lung and systemic circulation by Marshall, JL

“…The response is characterised by a local innate and adaptive lymphocytosis by day 7, and rapid upregulation of MHC-II antigen presentation differential gene expression pathways and Th1 effector function. …”

De novo transcriptome assembly and discovery of drought-responsive genes in white spruce ( Picea glauca ) by Ribeyre, Z, Depardieu, C, Prunier, J, Pelletier, G, Parent, GJ, Mackay, J, Droit, A, Bousquet, J, Nolet, P, Messier, C

“…We assembled a de novo transcriptome, performed differential gene expression analyses at four time points over 22 days during a controlled drought stress experiment involving 2-year-old plants and three genetically distinct clones, and conducted gene enrichment analyses. …”

Understanding early molecular mechanisms of abnormal myelination in neurological conditions by characterising Ermin deficiency by Oh, Sher Li, Ziaei, Amin, Tan, Liang Juin, Utami, Kagistia Hana, Pouladi, Mahmoud A., Langley, Sarah Raye

“…We studied the transcriptome of Ermin-deficient mice using gene co-expression and differential gene expression analyses to investigate early transcriptional effects of Ermin deficiency across age and sex. …”
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Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.

“…Our data in sham-operated young and aged mice reveal an age-associated decline in cerebral blood flow and differential gene expression. In fact, BCAS and aging caused broadly similar effects. …”
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