Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients by Claire L. Ihle, Meredith D. Provera, Desiree M. Straign, E. Erin Smith, Susan M. Edgerton, Adrie Van Bokhoven, M. Scott Lucia, Philip Owens

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Spatially-resolved proteomics and transcriptomics: An emerging digital spatial profiling approach for tumor microenvironment by Wang Nan, Wang Rongshui, Zhang Xue, Li Xia, Liang Yan, Ding Zhiyong

Subjects: “…digital spatial profiling…”
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Challenges and Opportunities for Immunoprofiling Using a Spatial High-Plex Technology: The NanoString GeoMx® Digital Spatial Profiler by Sharia Hernandez, Rossana Lazcano, Alejandra Serrano, Steven Powell, Larissa Kostousov, Jay Mehta, Khaja Khan, Wei Lu, Luisa M. Solis

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RUNX2 as a novel biomarker for early identification of patients progressing to advanced-stage mycosis fungoides by Maria Danielsen, Thomas Emmanuel, Morten Muhlig Nielsen, Lise Maria Lindahl, Maria Gluud, Niels Ødum, Line Raaby, Line Raaby, Torben Steiniche, Lars Iversen, Rikke Bech, Terkild Brink Buus, Claus Johansen

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Spatial Transcriptomics in Inflammatory Skin Diseases Using GeoMx Digital Spatial Profiling: A Practical Guide for Applications in Dermatology by Christina Cho, Nazgol-Sadat Haddadi, Michal Kidacki, Gavitt A. Woodard, Saeed Shakiba, Ümmügülsüm Yıldız-Altay, Jillian M. Richmond, Matthew D. Vesely

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Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis by Mark B. Wiley, Jessica Bauer, Valentina Alvarez, Kunaal Mehrotra, Wenxuan Cheng, Zoe Kolics, Michael Giarrizzo, Komala Ingle, Agnieszka B. Bialkowska, Barbara Jung

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Distinct spatial landscapes in clear-cell renal cell carcinoma as revealed by whole transcriptome analysis by J.I. López, M.F. Hogan, B. Sutton, S.E. Church, J.C. Angulo, C.E. Nunes-Xavier

Subjects: “…digital spatial profiling…”
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Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling by Jamie M. Walker, Shiva Kazempour Dehkordi, Anna Fracassi, Alison Vanschoiack, Anna Pavenko, Giulio Taglialatela, Randall Woltjer, Timothy E. Richardson, Habil Zare, Miranda E. Orr

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High multiplex analysis of the immune microenvironment in bone marrow trephine samples using GeoMX™ digital spatial profiling by R.M. Koldej, D.S. Ritchie

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Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer by William P. Duggan, Batuhan Kisakol, Ina Woods, Mohammedreza Azimi, Heiko Dussmann, Joanna Fay, Tony O’Grady, Barry Maguire, Ian S. Reynolds, Manuela Salvucci, Daniel J. Slade, Deborah A. McNamara, John P. Burke, Jochen H.M. Prehn

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Spatial proteomic profiling of tumor and stromal compartments in non‐small‐cell lung cancer identifies signatures associated with overall survival by Vahid Yaghoubi Naei, James Monkman, Habib Sadeghirad, Ahmed Mehdi, Tony Blick, William Mullally, Ken O'Byrne, Majid Ebrahimi Warkiani, Arutha Kulasinghe

Subjects: “…digital spatial profiling…”
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Molecular analysis of XPO1 inhibitor and gemcitabine–nab‐paclitaxel combination in KPC pancreatic cancer mouse model by Md. Hafiz Uddin, Mohammad Najeeb Al‐Hallak, Husain Yar Khan, Amro Aboukameel, Yiwei Li, Sahar F. Bannoura, Gregory Dyson, Seongho Kim, Yosef Mzannar, Ibrahim Azar, Tanya Odisho, Amr Mohamed, Yosef Landesman, Steve Kim, Rafic Beydoun, Ramzi M. Mohammad, Philip A. Philip, Anthony F. Shields, Asfar S. Azmi

Subjects: “…digital spatial profiling…”
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Spatially resolved gene expression profiles of fibrosing interstitial lung diseases by Seung J. Kim, Matthew J. Cecchini, Elissa Woo, Nathashi Jayawardena, Daniel T. Passos, Frederick A. Dick, Marco Mura

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Identifying prognostic markers in spatially heterogeneous breast cancer microenvironment by Guohong Liu, Liping Wang, Lili Ji, Dan He, Lihua Zeng, Guangzheng Zhuo, Qian Zhang, Dujuan Wang, Yunbao Pan

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Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies by Tim Bathe, Gabriela P. Hery, Jonathan A. B. Villareal, Jennifer L. Phillips, Eric M. Cohen, Rohan V. Sharma, Wangchen Tsering, Stefan Prokop

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The Technical Feasibility of Digital Spatial Profiling in Immune/Inflammation Study of Thrombosis by Jiang J, Liu Y

Subjects: “…digital spatial profiling…”
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Tumor and α‐SMA‐expressing stromal cells in pancreatic neuroendocrine tumors have a distinct RNA profile depending on tumor grade by Helvijs Niedra, Raitis Peculis, Rihards Saksis, Ilona Mandrika, Sofija Vilisova, Jurijs Nazarovs, Austra Breiksa, Aija Gerina, Julie Earl, Ignacio Ruz‐Caracuel, Marta Gabriela Rosas, Aldis Pukitis, Natalja Senterjakova, Vita Rovite

Subjects: “…digital spatial profiling…”
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Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients With Ulcerative Colitis by Dongping Lyu, Dongping Lyu, Guanjun Kou, Guanjun Kou, Shiyang Li, Shiyang Li, Shiyang Li, Lixiang Li, Lixiang Li, Lixiang Li, Bing Li, Bing Li, Ruchen Zhou, Ruchen Zhou, Xiaoxiao Yang, Xiaoxiao Yang, Wenyu Tian, Yanqing Li, Yanqing Li, Yanqing Li, Xiuli Zuo, Xiuli Zuo, Xiuli Zuo

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Intra-tumour heterogeneity of diffuse large B-cell lymphoma involves the induction of diversified stroma-tumour interfaces by Sabina Sangaletti, Fabio Iannelli, Federica Zanardi, Valeria Cancila, Paola Portararo, Laura Botti, Davide Vacca, Claudia Chiodoni, Arianna Di Napoli, Cesare Valenti, Celeste Rizzello, Maria Carmela Vegliante, Federica Pisati, Alessandro Gulino, Maurilio Ponzoni, Mario Paolo Colombo, Claudio Tripodo

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An integrated model of acinar to ductal metaplasia-related N7-methyladenosine regulators predicts prognosis and immunotherapy in pancreatic carcinoma based on digital spatial profi... by Hao Yang, Julia Messina-Pacheco, Andrea Liliam Gomez Corredor, Alex Gregorieff, Jun-li Liu, Ali Nehme, Ali Nehme, Hamed S. Najafabadi, Hamed S. Najafabadi, Yasser Riazalhosseini, Yasser Riazalhosseini, Bo Gao, Zu-hua Gao

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