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53501
Evaluation of stingless bee honey from Heterotrigona itama Cockerell as anti-obesity agent in high fat diet-induced obesity Sprague-Dawley rat model
Published 2017“…As a conclusion, the intervention study suggested that administration of stingless bee honey was successful to reduce the complication risks related to obesity such as liver disease. Our study also suggests that stingless bee honey possesses hepatoprotective action that could be used to control obesity by regulating lipid metabolism.…”
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Thesis -
53502
Efficacy of oral intake of haruan [Channa striatus (Bloch, 1793)] extract versus glucosamine sulfate on knee osteoarthritis
Published 2019“…Knee osteoarthritis (OA) is the most prevalent degenerative arthritis and currently there are no pharmacological agents that able to retard the disease progressions. Channa striatus (CS) is a freshwater fish and its potential for treating knee OA has been explored but no comparison study has been done with glucosamine (GlcN), which has been widely used to treat osteoarthritis. …”
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Thesis -
53503
Effects of ethanolic extracts from Tinospora crispa (L) Hook.f. & Thomson and Andrographis paniculata (Burm.f.) Nees on the in vitro lytic cycle of Toxoplasma gondii infection
Published 2019“…This study showed that the EEAP and EETC contain promising drug candidates effective against T. gondii and safe to the host cells and can potentially be used in the future for the development of a potent antitoxoplasma compound that can target the protein kinase genes involved in the lytic cycle of the T. gondii parasite to prevent disease progression.…”
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Thesis -
53504
Limitations of existing dialysis diet apps in promoting user engagement and patient self-management: quantitative content analysis study
Published 2020“…Methods: This study consisted of a quantitative content analysis of commercial dialysis diet apps downloaded from Google Play and the Apple App Store available in the Asian marketplace, searched for using the following keywords in English: dialysis diet and diet for kidney disease. Free and paid apps available in English that provide nutrition information for adult dialysis patients were included. …”
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Article -
53505
Genetic polymorphisms of endothelial marker, connexin and acyl-CoA genes among ethnic Malay subjects with essential hypertension
Published 2020“…Genetic polymorphism and gene expression are serve as molecular biomarkers for the detection of the individual at risk of developing the disease. This association study included 177 of subjects without EH as control and 97 of subjects with EH as case. …”
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Thesis -
53506
Antioxidant properties and cytotoxicity of successively macerated Christia vespertilionis (L.f) Bakh.f. root and leaf against breast cancer cell lines
Published 2020“…Breast cancer is slowly moving into the category of chronic disease due to various barrier limitations such as poor prognosis, non- specific treatment and silent metastasis. …”
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Thesis -
53507
Assessment of pathogenicity of community-acquired methicillin-resistant Staphylococcus aureus isolates in peritonitis-induced mice
Published 2019“…aureus contributed for the greatest number of positive peritonitis cultures from patients with continuous ambulatory peritoneal dialysis and end-stage renal disease. Since the presence of CA-MRSA is continuously emerging, it is important to continue monitoring the distribution pattern and the pathogenic status of CA-MRSA in the community. …”
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Thesis -
53508
Effects of adolescent asthma education intervention on asthma control in Northwest of Libya
Published 2020“…Despite most national guidelines consider education as an essential component of effective asthma self-management to promote asthma control and reducing negative impact of this disease on daily life, a little number of educational programs target asthmatic adolescents in Libya. …”
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Thesis -
53509
Genetic determinants of TAC chemotherapy response in triple negative breast cancer patients
Published 2018“…The treatment response and disease outcome of the patients were evaluated after completion of chemotherapy. …”
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Thesis -
53510
Osteoclast-specific marker nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 expression in stage III giant cell tumor of the bone
Published 2018“…The mean value of NFATc1 expression was found to be statistically not significant when tested against the risk of pulmonary metastases and recurrence disease, making it not a useful marker to predict the risk of recurrence and pulmonary metastases in aggressive type of GCTB. …”
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Thesis -
53511
Gross anatomy learning using radiological images (galeri) : its impact on first-year medical students' comprehension, engagement, and cognitive load
Published 2021“…Furthermore, the Coronavirus disease 2019 (COVID-19) pandemic has resulted in the lack of kinaesthetic experience in anatomy learning, and thus making it less engaging. …”
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Thesis -
53512
The role of health self-efficacy, health assertiveness, and risk perception on the relationship between vaccination knowledge and vaccination intention
Published 2022“…However, a concerning trend of vaccine-preventable disease incidence and vaccine hesitancy demand the need for better health promotion interventions. …”
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Thesis -
53513
Nuclear factor kappa b genetic polymorphisms and association with colorectal cancer susceptibility risk in malaysian population - A molecular epidemiology study
Published 2013“…CRC is a multifactor caused disease resulting from complex interaction between environmental and genetic predisposition factors. …”
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Thesis -
53514
Molecular analysis of the promoter and the core promoter region Of the smn2 gene in circumscribing the clinical severity of sma
Published 2012“…The isoform to this gene, SMN2, with mutation in 1 base pair, encodes for 10% of FL-SMN protein and is reported to decrease the severity of the disease when there is an increase gene dosage. There are 3 clinical types of SMA; type I, type II and type III. …”
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Thesis -
53515
Development of compound clustering techniques using hybrid soft-computing algorithms
Published 2006“…Furthermore, it has been found that many of the biologically active molecular structures exhibit more than one activity in which case they can be used as drugs for the treatment of more than one disease. However, previous clustering methods on chemical compounds are mostly limited to hard partitioning, which allows a compound to belong to only one cluster. …”
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Monograph -
53516
En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy
Published 2015“…This in vivo documentation of the RPE and choroidal vasculature at variable depths may help elucidate the pathophysiology of disease and can contribute to the diagnosis and management of chronic CSCR.…”
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Article -
53517
Automated telephone communication systems for preventive healthcare and management of long‐term conditions
Published 2018“…Objectives: To assess the effects of ATCS for preventing disease and managing long‐term conditions on behavioural change, clinical, process, cognitive, patient‐centred and adverse outcomes. …”
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Journal Article -
53518
Health, lifestyle, and psycho-social determinants of poor sleep quality during the early phase of the COVID-19 pandemic : a focus on UK older adults deemed clinically extremely vul...
Published 2021“…Significant associations with poor sleep included health/medical factors: COVID-19CEV status, higher BMI, arthritis, pulmonary disease, and mental health disorders; and the following lifestyle and psychosocial factors: living alone, higher alcohol consumption, an unhealthy diet and higher depressive and anxiety symptoms. …”
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Journal Article -
53519
Student assistantship programme : an evaluation of impact on readiness to transit from medical student to junior doctor
Published 2022“…Readiness to be first respondents in ten acute situations improved (statistically significant for asthma, chronic obstructive pulmonary disease exacerbation, gastrointestinal bleed, sepsis, and adverse drug reactions). …”
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Journal Article -
53520
Genomic history and forensic characteristics of Sherpa highlanders on the Tibetan Plateau inferred from high-resolution InDel panel and genome-wide SNPs
Published 2022“…Finally, natural-selection signals revealed via iHS, nSL and iHH12 showed natural selection signatures associated with disease susceptibility in Sherpas. Generally, we provided the comprehensive landscape of admixture and evolutionary history of Sherpa people based on the shared alleles and haplotypes from the InDel-based genotype data and high-density genome-wide SNP data. …”
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Journal Article