Hack des IT-Rechts: Zu den Folgen des „Doxing-Falls“ by Sebastian J. Golla

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Rationally Designed Oral DOX Gels for Colon-Specific Administration by Jie Li, Luping Ma, Cheng Wang, Pengju Jiang, Pengfei Cui, Jianhao Wang

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The Defects of Epigenetic Reprogramming in Dox-Dependent Porcine-iPSCs by Aiwen Jiang, Yangyang Ma, Xue Zhang, Qianqian Pan, Pengfei Luo, Hongyun Guo, Wangjun Wu, Juan Li, Tong Yu, Honglin Liu

“…This study reveals the aberrant epigenetic reprogramming during dox-dependent piPSCs formation, which lays the foundation for research of porcine-iPSC reprogramming and genome imprinting.…”
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A decade's worth of impact: Dox loaded liposomes in anticancer activity by Puja Ghosh, Himja Tiwari, Jaya Lakkakula, Arpita Roy, Talha Bin Emran, Summya Rashid, Saad Alghamdi, Bodour S. Rajab, Mazen Almehmadi, Mamdouh Allahyani, Abdulelah Aljuaid, Ahad Amer Alsaiari, Rohit Sharma, Ahmad O. Babalghith

“…Among them, DOX encapsulated liposomes gained popularity because of their clinical success and lower toxicity. …”
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TPGS2000-DOX Prodrug Micelles for Improving Breast Cancer Therapy by Tang L, Jiang W, Wu L, Yu X, He Z, Shan W, Fu L, Zhang Z, Zhao Y

“…Increasing the targeting ability of DOX and reducing the multi-drug resistance (MDR) of tumor cells to DOX are major aims for researchers.Purpose: In this study, to increase therapeutic efficiency, reduce the side effects and the MDR of tumor cells to DOX, D-alpha-tocopheryl polyethylene glycol 2000 succinate monoester (TPGS2000)-DOX prodrug micelles were developed by grafting DOX to TPGS2000 via an amide bond that release DOX in the slightly acidic conditions in tumor tissue.Materials and Methods: The TPGS2000-DOX micelles were constructed using polyethylene glycol 12-hydroxy stearate (Solutol HS15) as the carrier. …”
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The Impact of Surface Drug Distribution on the Acoustic Behavior of DOX-Loaded Microbubbles by Chia-Wei Lin, Ching-Hsiang Fan, Chih-Kuang Yeh

“…We found that the DOX loading capacity of MBs was determined by the proportion of DSPG, since there was an electrostatic interaction with DOX. …”
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Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis by Hiroki Kitakata, Jin Endo, Hidehiko Ikura, Hidenori Moriyama, Kohsuke Shirakawa, Yoshinori Katsumata, Motoaki Sano

“…Doxorubicin (DOX) is the most widely used anthracycline anticancer agent; however, its cardiotoxicity limits its clinical efficacy. …”
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A Ticklish Parrot-dox: Dual Diagnosis of Lyme Carditis and Psittacosis by Paul Tran, Marah Mayah, Ryan MacLeod, Jennifer Frampton

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Brazilein Increased Cytotoxic Activity of Doxorubicin on MCF-7/DOX Cells by Ni Putu Linda Laksmiani, Ratna Asmah Susidarti, Edy Meiyanto

“…Keywords : brazilein, doxorubicin, MCF-7/DOX, cytotoxic.…”
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Multi-Stimuli-Responsive DOX Released from Magnetosome for Tumor Synergistic Theranostics by Tsai MF, Lo YL, Huang YC, Yu CC, Wu YT, Su CH, Wang LF

“…Truncated octahedral Fe3O4 nanoparticles (IONPs) were synthesized and encapsulated to produce IONPs-PSPps NPs and doxorubicin (DOX) was further loaded to produce IONPs-PSPps@DOX NPs for theranostic applications.Results: IONPs-PSPps NPs remained a superparamagnetic property with a saturation magnetization value of 85 emu⋅gFe3O4− 1 and a relaxivity value of 180 mM− 1⋅s− 1. …”
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Oxidative phosphorylation activation is an important characteristic of DOX resistance in hepatocellular carcinoma cells by Li Wu, Jiayu Zhao, Kexin Cao, Xiao Liu, Hao Cai, Jiaqi Wang, Weidong Li, Zhipeng Chen

“…Additionally, UPLC-MS/MS was used to determine the doxorubicin (DOX) content in SMMC-7721 and SMMC-7721/DOX cells. …”
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EGCG regulated osteolytic microenvironment to enhance the antitumor effect of DOX on orthotopic osteosarcoma by Dongcai Hu, KeJiang Lin, Xiang Gao, Mengxue Zhou, Huan Geng

“…In vivo, the combination of DOX and EGCG could reduce tumor volume and osteolysis destruction compared with the DOX treatment group. …”
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DOX-CONJUGATED HIGH-QUALITY AgZnInS QDs FOR REVERSAL OF MULTIDRUG RESISTANCE by LINGZHI QU, DAWEI DENG, JIE WANG, YUEQING GU

“…It, therefore, significantly enhanced the cytotoxicity of DOX to MDR cancer cells as the QDs could bring the DOX to nucleus.…”
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Lactosylated IR820/DOX Co-Assembled Nanodrug for Synergetic Antitumour Therapy by Jiang Y, Huang C, Luan Y

“…First, lactosylated IR820 (LA-IR820) was designed to target HCC. Then, the LA-IR820/DOX nanodrug (LA-IR820/DOX ND) was purely self-assembled without excipient assistance. …”
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LC-MS/MS Proteomic Study of MCF-7 Cell Treated with Dox and Dox-Loaded Calcium Carbonate Nanoparticles Revealed Changes in Proteins Related to Glycolysis, Actin Signalling, and Energy Metabolism by Hamidu Ahmed, Mokrish Ajat, Rana I. Mahmood, Rozaihan Mansor, Intan Shameha Abdul Razak, Jameel R. Al-Obaidi, Nurhanani Razali, Alhaji Zubair Jaji, Abubakar Danmaigoro, Md Zuki Abu Bakar

“…This study aimed to characterise and differentiate the proteomics profiles of breast cancer cell lines treated with Doxorubicin (DOX) and Doxorubicin-CaCO₃-nanoparticles (DOX-Ar-CC-NPs). …”
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Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound by Laura Spiers, Michael Gray, Paul Lyon, Shivan Sivakumar, Noor Bekkali, Shaun Scott, Linda Collins, Robert Carlisle, Feng Wu, Mark Middleton, Constantin Coussios

“…PanDox is designed as a Phase 1 single centre study to investigate enhancing drug delivery to adult patients with non-operable pancreatic ductal adenocarcinomas. …”
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Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound by Spiers, L, Gray, M, Lyon, P, Sivakumar, S, Bekkali, N, Scott, S, Collins, L, Carlisle, R, Wu, F, Middleton, M, Coussios, C

“…PanDox is designed as a Phase 1 single centre study to investigate enhancing drug delivery to adult patients with non-operable pancreatic ductal adenocarcinomas. …”

Magnetoliposomes with Calcium-Doped Magnesium Ferrites Anchored in the Lipid Surface for Enhanced DOX Release by Beatriz D. Cardoso, Diana E. M. Fernandes, Carlos O. Amorim, Vítor S. Amaral, Paulo J. G. Coutinho, Ana Rita O. Rodrigues, Elisabete M. S. Castanheira

“…After 48 h of testing, at pH 5.5, 67.5% ± 0.5% of DOX was released, while at pH 7.4, only a modest release of 27.0% ± 0.1% was achieved. …”
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Nano‐gold micelles loaded Dox and Elacridar for reversing drug resistance of breast cancer by Liu‐Jing Wen, Yue‐Sheng Wang, Jie Zhang

“…Nano‐gold micelles loaded with Dox and Elacridar (FP‐ssD@A‐E) were chemically synthesised. …”
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Multifunctional ZnO@DOX/ICG-LMHP Nanoparticles for Synergistic Multimodal Antitumor Activity by Zhuoyue Li, Jingru Wang, Junwei Liu, Jianming Yu, Jingwen Wang, Hui Wang, Qingchao Wei, Man Liu, Meiqi Xu, Zhenhan Feng, Ting Zhong, Xuan Zhang

“…Both DOX and ICG also induced immunogenic cell death (ICD) for immunotherapy. …”
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