Development and Performance Verification of the PBPK Model for Antazoline and Its Metabolite and Its Utilization for Pharmacological Hypotheses Formulating by Barbara Wiśniowska, Joanna Giebułtowicz, Roman Piotrowski, Piotr Kułakowski, Sebastian Polak

“…When used to feed the PD model (e.g., simulating ECG), concentration-time profiles predicted by the model enable the assessment of antazoline’s effect in various clinical scenarios with the possibility to account for population differences or CP mediated drug-drug interactions.…”
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Combined confocal Raman and quantitative phase microscopy system for biomedical diagnosis by Kang, Jeon Woong, Lue, Niyom, Kong, Chae-Ryon, Barman, Ishan, Dingari, Narahara Chari, Dasari, Ramachandra Rao, Feld, Michael S., Goldfless, Stephen Jacob, Niles, Jacquin

“…This new approach allows monitoring cell development and cell-drug interactions with minimal perturbation of the biological system of interest.…”
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Factors in determining seizure control in pediatric patients on antiepileptic medication: a review of the literature by Anaanthan Bhuvanendran Pillai, Azmi Mohd Tamil

“…Furthermore, there is certain factors that need to be explored in the future, such as unaddressed parental concern on treatment/medication, denial of disease and drug-drug interactions. Conclusions Factors that had been identified can be used in the prevention and control programs, while factors which is less studied should be further studied in the future.…”
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Isolation of Antidepressants and Their Metabolites from Saliva Using Supported Liquid Extraction (SLE) by Ewelina Dziurkowska, Marek Wesolowski

“…The determination of antidepressant drugs and their metabolites in the body, mainly in the blood, allows for the monitoring of drug levels and their metabolism, helps identify drug interactions, and reduces the likelihood of increased side effects. …”
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Pattern of Timing Adherence Could Guide Recommendations for Personalized Intake Schedules by Kurt E. Hersberger, Dimitrios A. Tsakiris, Michel Romanens, Isabelle Arnet, Philipp Walter

“…The complete delineation of timing adherence allows for the calculation of objective adherence parameters and the linking of exposure with drug-drug interactions. A sub-analysis was performed on 68 patients, who were prescribed lipid lowering therapy. …”
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Review of bosentan in the management of pulmonary arterial hypertension by Eli Gabbay, John Fraser, Keith McNeil

“…The safety and tolerability of bosentan as well as drug interactions are discussed. Dosage recommendations in adults and pediatrics are presented. …”
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Episodic memories and their relevance for psychoactive drug use and addiction by Christian P. Müller

“…In that, understanding how addictive drugs interact with episodic memory circuits in the brain may provide crucial information for how drug use and addiction are established.…”
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Chinese Herbal Medicine on Cardiovascular Diseases and the Mechanisms of Action by Cuiqing Liu, Yu Huang

“…Future research should focus on well-designed clinic trial, in-depth mechanic study, investigations on side effects of herbs and drug interactions. Studies on developing new agents with effectiveness and safety from traditional Chinese medicine is promising for prevention and treatment of patients with cardiovascular diseases.…”
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Treatment algorithms for special cases by Emel Bülbül Başkan

“…It should be noted that the elderly have comorbidities and concomitant drug use, which increases the likelihood of side effects and drug interactions of psoriasis medications. In the presence of a viral disease, many agents used in the treatment of psoriasis carry the risk of exacerbating the infection due to their immunosuppressive properties. …”
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Insomnia in general practice: the role of doxylamine by D. I. Burchakov, M. V. Tardov

“…We also discuss the pharmacology of doxylamine, drug interactions, and prescription modes. There are also three clinical case studies, presenting the typical acute insomnia patients and logic for their evaluation, underlining key clinical features of this disorder.…”
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Novos medicamentos antiepilépticos. by J Pimentel, F Pinto

“…Yet, the ideal AE, that is, with a well-known mechanism of action, effective in monotherapy for all epileptic fits, with a perfect pharmacokinetic profile, with no adverse or teratogenic effects, with no drug interactions and available under many formulations, is far from being developed. …”
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Progress in the Treatment of Antisense Oligonucleotides in Duchenne Muscular Dystrophy by XU Tingting, ZUO Wei, LIU Xin, FAN Qianqian, GAO Yang, LIANG Chunsu, ZHANG Bo

“…In addition, the likelihood of drug-drug interactions of ASO is low. Existing clinical studies have shown that they have certain clinical benefits and good tolerability, bringing new options for DMD treatment. …”
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Increased amisulpride serum concentration in a patient treated with concomitant pregabalin and trazodone: a case report by Petr Potměšil, Lenka Kostýlková, Miloslav Kopeček

“…This could be helpful information for psychiatrists in order to avoid drug–drug interactions between amisulpride and pregabalin. We recommend TDM of amisulpride in patients treated concomitantly with other drugs eliminated mainly by the kidneys.…”
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The Use of Direct Oral Anticoagulants for Prevention of Stroke and Systemic Embolic Events in East Asian Patients with Nonvalvular Atrial Fibrillation by Chang-Sheng Ma

“…DOACs do not require monitoring of the international normalized ratio to determine the optimal dose, and have a lower potential for food and drug interactions, improved benefit-risk profiles, and a quicker onset and offset of action relative to warfarin. …”
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Polypharmacy in Outpatients with Bipolar Disorder: Associated Factors and Treatment Characteristics in Türkiye by Nihan Küçük, Fatma Çoker, Neriman Aras

“…Moreover, interventions are needed to minimize the possible side effects, and risk of drug-drug interactions related to the use of multiple drugs, determine the benefit/harm ratio and reduce unnecessary psychotropic drug use.…”
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Physicians’ knowledge and communication about traditional, complementary and alternative medicine use among Latino patients at Kaiser Permanente, Oakland CA by Ingrid Bauer, Juan J. Guerra

“…Physicians were more concerned with the misuse of prescription drugs among Latino patients than the potential for herbal toxicity or herb-drug interactions. The results indicate a need to include questions about pharmaceuticals in future research on Latino health practices, and also point to the need for research on how education, income and acculturation affect health beliefs and TCAM practices within different Latino subgroups.…”
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Recent findings and advancements in the detection of designer benzodiazepines: a brief review by Wu Dihua, Fu Li

“…Further research should focus on elucidating their pharmacokinetic properties and metabolism in humans, especially in view of genetic polymorphisms and drug interactions that could inform clinical treatment choices. …”
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Topical issues of the efficiency and safety of using the first direct thrombin inhibitor in real clinical practice by A. V. Fonyakin

“…An increased risk for bleeding was generally associated with undesirable drug interactions, polypragmasia, and underestimated kidney dysfunction. …”
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The Algorithm of Herbal Medicine Usage in Nursing Homes, Isfahan, Iran by Zohreh Bakhtiyari

“…They commonly face drug interactions as well. On the other hand, most of the elderly believe in the effects of medicinal plants and widely use them to treat their diseases. …”
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Polypharmacy is a challenge for our generation, and the knowledge of deprescribing is a needed skill of our health care professionals by Shadi Sarahroodi

“…Polypharmacy is frequently linked to adverse drug reactions (ADR), drug interactions, falls, prescribing cascades, patient non-adherence to medications, and even more severe outcomes such as hospitalisation and death. …”
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