Opportunities, Challenges and Pitfalls of Using Cannabidiol as an Adjuvant Drug in COVID-19 by Barbara Malinowska, Marta Baranowska-Kuczko, Aleksandra Kicman, Eberhard Schlicker

“…However, one should be aware of side effects of CBD (which are rarely serious), drug interactions (also extending to drugs acting against COVID-19) and the proper route of its administration (vaping may be dangerous). …”
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Interactions between Immunosuppressive Therapy and Direct-Acting Antivirals in Kidney Transplant Recipient with Hepatitis C Infection by Paolo Carta, Federica Curci, Leonardo Caroti, Larti Aida, Lorenzo Di Maria, Lino Cirami

“…DAAs give encouraging results in the eradication of HCV in renal transplant recipients, although they are associated with potential adverse drug interactions. The preliminary data of our study suggest that it is not necessary to change the dose of immunosuppressive drugs during therapy and that creatinine and proteinuria remain stationary. …”
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Mebendazole Inhibits <i>Histoplasma capsulatum</i> In Vitro Growth and Decreases Mitochondrion and Cytoskeleton Protein Levels by Marcos Abreu Almeida, Andrea Reis Bernardes-Engemann, Rowena Alves Coelho, Camila Jantoro Guzman Lugones, Iara Bastos de Andrade, Dario Corrêa-Junior, Simone Santiago Carvalho de Oliveira, André Luis Souza dos Santos, Susana Frases, Márcio Lourenço Rodrigues, Richard Hemmi Valente, Rosely Maria Zancopé-Oliveira, Rodrigo Almeida-Paes

“…Itraconazole and amphotericin B are used to treat histoplasmosis; however, both antifungals have potentially severe pharmacokinetic drug interactions and toxicity. The present study determined the minimal inhibitory and fungicidal concentrations of mebendazole, a drug present in the NIH Clinical Collection, to establish whether it has fungicidal or fungistatic activity against <i>Histoplasma capsulatum</i>. …”
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Favipiravir Use in COVID-19 Treatment by Emre KARA, Ahmet Çağkan İNKAYA, Kutay DEMİRKAN, Serhat ÜNAL

“…In the scope of the review, under the title of pharmacology of favipiravir, adverse effects and drug interactions in addition to pharmacokinetic and pharmacodynamic properties are mentioned. …”
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Entrectinib, a new multi-target inhibitor for cancer therapy by Qinghua Jiang, Mingxue Li, Hua Li, Lixia Chen

“…In this review, we give a brief introduction to TKK, ROS1 and ALK, and on this basis, we give a detailed and comprehensive introduction to the mechanism of action, pharmacokinetics, pharmacodynamics, clinical efficacy, tolerability and drug interactions of entrectinib.…”
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Phytoconstituents and Pharmacological Activities of Indian Camphorweed (<i>Pluchea indica</i>): A Multi-Potential Medicinal Plant of Nutritional and Ethnomedicinal Importance by Sabrin R. M. Ibrahim, Alaa A. Bagalagel, Reem M. Diri, Ahmad O. Noor, Hussain T. Bakhsh, Gamal A. Mohamed

“…However, further studies on the drug interactions, mechanism of action, pharmacokinetics, toxicology, and metabolism, as well as clinical trials, should be carried out.…”
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Biocompatible PEO-b-PCL Nanosized Micelles as Drug Carriers: Structure and Drug–Polymer Interactions by Angeliki Chroni, Thomas Mavromoustakos, Stergios Pispas

“…Light scattering and nuclear magnetic resonance (NMR) provide information on micelle structure and polymer–drug interactions. According to dynamic light scattering (DLS) analysis, the PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers formed nanostructures in the range of 17–26 nm in aqueous milieu. …”
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Prevention and Management of Infections in Lung Transplant Recipients by Anum Fayyaz, Mohammed Raja, Yoichiro Natori

“…One must also be vigilant about drug interactions of antibiotics and immunosuppressive agents. …”
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Mycobacterium Tuberculosis Infection after Kidney Transplantation: A Comprehensive Review by Bogdan Marian Sorohan, Gener Ismail, Dorina Tacu, Bogdan Obrișcă, Gina Ciolan, Costin Gîngu, Ioanel Sinescu, Cătălin Baston

“…Regarding treatment challenges in KT recipients with TB, drug interactions, drug toxicities and therapeutical adherence must be considered.…”
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Adsorption of the rhNGF Protein on Polypropylene with Different Grades of Copolymerization by Paolo Canepa, Claudio Canale, Ornella Cavalleri, Giovanni Marletta, Grazia M. L. Messina, Massimo Messori, Rubina Novelli, Simone Luca Mattioli, Lucia Apparente, Nicola Detta, Tiziana Romeo, Marcello Allegretti

“…The surface properties of drug containers should reduce the adsorption of the drug and avoid packaging surface/drug interactions, especially in the case of biologically-derived products. …”
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Pattern of Drugs and Therapeutic Agents Exposure among Pediatric Inpatients in the Fatima University Medical Center by N Subedi, B Shrestha, S Poudel, A Bhattarai, Namrata KC

“…The most common results of many drugs and therapeutic agents are increased adverse drug reactions, drug-drug interactions and higher costs. Objectives: To assess the prevalence and patterns of exposure to drugs and therapeutic agents among pediatric inpatients. …”
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HIV and an Ageing Population—What Are the Medical, Psychosocial, and Palliative Care Challenges in Healthcare Provisions by Mohamed H. Ahmed, Fatima Ahmed, Abu-Bakr Abu-Median, Maria Panourgia, Henry Owles, Bertha Ochieng, Hassan Ahamed, Jane Wale, Benjamin Dietsch, Dushyant Mital

“…The treatment of such conditions may lead to polypharmacy and may increase the risk of cART drug–drug interactions. In addition, the risk of developing infection and cancer is high. …”
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Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods by Maria Miguel Coelho, Carla Fernandes, Fernando Remião, Maria Elizabeth Tiritan

“…The choice of models for pharmacokinetic studies as well as the subsequent data interpretation must also be aware of genetic factors (such as polymorphic metabolic enzymes), sex, patient age, hepatic diseases, and drug interactions. Therefore, the pharmacokinetics and toxicity of a racemate or an enantiomerically pure drug are not equal and need to be studied. …”
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Evaluation of Trigger Tool Methodology Related to Adverse Drug Events in Hospitalized Patients by Sara Kolc Brown, Jacob Peterson, Shayne Harris Schiedel, Kari Vavra Janes

“…Summary: The positive predictive value (PPV) for elevated INR was 35% (confidence interval [CI] 21–53%), hypoglycemia was 70.4% (CI 62–78%), and 53% for naloxone administration (CI 45–60%). Drug interactions were the most common factor that may have contributed to an ele-vated INR, with a mean INR of 7.9. …”
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Anti-Pseudomonas aeruginosa activity of natural antimicrobial peptides when used alone or in combination with antibiotics by Xueqi Chen, Shan Su, Yan Yan, Limei Yin, Lihong Liu

“…This review particularly focuses on summarizing the inhibitory activity of natural antimicrobial peptides against P. aeruginosa planktonic cells and biofilms, as well as the drug interactions when these peptides used in combination with conventional antibiotics. …”
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Pharmacology of Free Fatty Acid Receptors and Their Allosteric Modulators by Manuel Grundmann, Eckhard Bender, Jens Schamberger, Frank Eitner

“…While the majority of marketed GPCR drugs interact exclusively with the orthosteric binding site, allosteric mechanisms in GPCR biology stay medically underexploited, with only several allosteric ligands currently approved. …”
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Assessing insomnia management in community pharmacy setting in Jordan: A simulated patient approach. by Mayyada Wazaify, Eman Elayeh, Razan Tubeileh, Eman A Hammad

“…No information was provided in relation to potential drug interactions or contraindications. No advice was offered on lifestyle or good sleeping hygiene. …”
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rTMS efficacy in major depression disorder: comparing two reviews by S. Yasmine, B. A. Hanen, B. O. Fatma, A. Amal, K. Emira, M. Leila

“…The body of TMS literature suggests that daily, left prefrontal TMS for 3–6 weeks has antidepressanteffects that are clinically meaningful (30% remission), with low side effects and nodrug-drug interactions. Furthermore, TMS shows promise in several other psychiatricdisorders, particularly treating acute and chronic pain. …”
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Bidirectional pharmacokinetics of doravirine, tenofovir, and feminizing hormones in transgender women (IDentify): A randomized crossover trial by Kevin Lam, Walter K. Kraft, Tingting Zhan, Edwin Lam

“…Abstract Transgender women may have concerns of drug interactions between feminizing hormone therapy (FHT) and antiretrovirals, leading to nonadherence. …”
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Pharmacological Efficacy of Ginseng against Respiratory Tract Infections by Abdulrhman Alsayari, Abdullatif Bin Muhsinah, Dalia Almaghaslah, Sivakumar Annadurai, Shadma Wahab

“…Further analysis needs to be re-focused on clinical trials to study ginseng’s efficacy and safety in treating pathogenic infections and in determining ginseng-drug interactions.…”
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