The Relationship Between the Use of Medicinal Plants and Medication Adherence in the Elderly with Chronic Diseases by Hamid Reza Koohestani, Nayereh Baghcheghi

“…Conclusion Due to the high consumption of medicinal plants in the elderly with chronic diseases and its relationship with poor medication adherence, it is necessary to educate them about the correct use of medicinal plants, their side effects, herb-drug interactions, the need to inform the doctor about use of medicinal plants, and adherence to medication.…”
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Rate of Herbal Medicines Use during Pregnancy and some related Factors in Women of Ahvaz, Iran: 2017 by Samereh Soleymani, Somayeh Makvandi

“…However, consumption of some plants may cause side effects in mother and fetus or lead to drug interactions. The aim of this study was to investigate the rate if using herbal medications during pregnancy and some of the related factors in Ahvaz, Iran. …”
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Clinical experience with piribedil in chronic cerebrovascular disease with cognitive impairment by E. V. Moroz, T. A. Zakharycheva, M. V. Antonyuk

“…The investigation revealed that the drug had a good tolerability, neither adverse events nor drug-drug interactions. Conclusion. When used in CCVD and CI, piribedil 50 mg once daily for 3 months is able to improve cognitive functions in elderly patients, which indicates that it is feasible to use the drug in combined therapy with essential (antihypertensive, lipid-lowering, antithrombotic) medicines.…”
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Accuracy of the electronic health record’s problem list in describing multimorbidity in patients with heart failure in the emergency department by Brandon L. King, Michelle L. Meyer, Srihari V. Chari, Karen Hurka-Richardson, Thomas Bohrmann, Patricia P. Chang, Jo Ellen Rodgers, Jan Busby-Whitehead, Martin F. Casey

“…Rapid assessment of multimorbidity is important for minimizing the risk of harmful drug-disease and drug-drug interactions. We assessed the accuracy of using the electronic health record (EHR) problem list to identify comorbid conditions among patients with chronic HF in the emergency department (ED). …”
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Assessment of novel oral anticoagulant use within a community teaching hospital by Sultan Alghadeer, Lori Hornsby

“…Background: Novel oral anticoagulants (NOACs) are considered to be at least as effective and safe as warfarin with several advantages such as predictable pharmacokinetics, allowing for standardized dosing without monitoring, a lack of food interactions and fewer drug interactions; however, their misuse could potentially result in patient harm. …”
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Study of Hepatoprotective Effect of Silymarin and Ursodeoxycholic Acid in Chronic Hepatitis C Patients by Shahira Fawzy El Menshawe, Amira Shaban Ahmed, Lamiaa Nagy Abdel Aty, Mohamed Ahmed Abo Seif

“…Although, the novel direct-acting antiviral agents(DAAs) telaprevir, and boceprevir has dramatically improved SVR rates; issues such as adverse reactions, frequent dosing, and drug interactions still represent a challenge. Even overcoming these challenges with the new revolutionary development of sofosbuvir, its high cost still needs to be addressed. …”
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From hormone replacement therapy to regenerative scaffolds: A review of current and novel primary hypothyroidism therapeutics by Maria Heim, Maria Heim, Ian J. Nixon, Elaine Emmerson, Anthony Callanan

“…Additional complications are also present in the form of dosage difficulties, extensive drug interactions and poor patience compliance. The alternative therapeutic approach employed in the past is combination therapy, which consists of administration of both T3 and T4, either synthetic or in the form of desiccated thyroid extract. …”
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The complex issue of medication management in older persons: a challenge for nurses by Carmen Maria Vitiello, Yari Longobucco, Sofia Espinoza Tofalos, Mauro Di Bari

“…This review addresses the main issues related to pharmacotherapy in late life, such as pharmacokinetics and pharmacodynamics changes, limitations of evidence-based medicine, polypharmacy, drug interactions, adverse drug reactions, and lack of adherence. …”
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Prevalence of Drugs and Drug Combinations that Increase Risk of Prolonged QT Time Among People with Major Neurocognitive Disorder Living in Sweden: A Cross-Sectional Registry Study by Maria Gustafsson, Muna Altufaili, Maria Sjölander

“…Objective The aim of this study was to investigate the prevalence of QT-prolonging drugs and QT-prolonging drug–drug interactions and associated factors among older people with major neurocognitive disorder. …”
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Investigation of DRD2 and HTR2A mRNA Expression in Two Therapeutic States of Antipsychotic Polypharmacy and Aripiprazole Monotherapy in the Peripheral Blood of Patients With Schizo... by Arash Mirabzadeh, Hamid Reza Iranpour, Hamid Reza Khorram Khorshid, Davood Zare-Abdollahi, Mehdi Norouzi, Venus Vatankhah

“…Notwithstanding the suggestion for treating schizophrenia with a minimum dose of drugs, antipsychotic polypharmacy increases the patient’s care costs and drug interactions. Aripiprazole reduces the metabolic side effects of antipsychotic polypharmacy treatment. …”
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Clinical pharmacists’ interventions and therapeutic drug monitoring in patients with mycobacterial infections by Anna M. Woods, Kristin C. Mara, Christina G. Rivera

“…Conclusion: Clinical pharmacists should be involved in this complex care to optimize medication management through identification of drug interactions, tailoring antimicrobial dosing, managing TDM results, and providing adherence counseling.…”
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Quality of life and associated factors among people receiving second-line anti-retroviral therapy in Johannesburg, South Africa by Nomcebo Oratile Mokgethi, Nicola Christofides, Mercilene Machisa, Godspower Akpomiemie, Samantha Lalla-Edward

“…Therefore, QOL could be enhanced by considering PLH characteristics, clinical factors such as regimen side-effects profile, management of comorbid conditions and mitigating risks such as potential adverse drug-to-drug interactions among patients on ART.…”
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Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation by Abdelfattah Hassan, Ahmed M. Mosallam, Amal O. A. Ibrahim, Mohamed Badr, Aboubakr H. Abdelmonsef

“…Abstract Multitarget anticancer drugs are more superior than single target drugs regarding patient compliance, drug adverse effects, drug-drug interactions, drug resistance as well as pharmaceutical industry economics. …”
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Drug-related problems and factors influencing acceptance of clinical pharmacologists’ alerts in a large cohort of neurology inpatients by Anne B Taegtmeyer, Ivanka Curkovic, Natascia Corti, Christoph Rosen, Marco Egbring, Stefan Russmann, Andreas R Gantenbein, Michael Weller, Gerd A Kullak-Ublick

“…Factors associated with an increased likelihood of acceptance were prescriptions involving regularly administered drugs (odds ratio [OR] 2.57 95% confidence interval [CI] 1.73–3.80), adverse drug events (OR 2.5; 95% CI 1.29–5.06), known drug side-effect (OR 1.85; 95% CI 1.06–3.22), high-risk drug-drug interactions (OR 3.22; 95% CI 1.07–9.69) and interventions involving changing a drug (OR 2.71; 95% CI 1.17–6.25). …”
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Use of Janus kinase inhibitors in the treatment of immunoinflammatory rheumatic diseases: safety issues by B. S. Belov, N. V. Muravyeva, G. M. Tarasova, M. M. Baranova

“…In the present article, issues related to various aspects of the safety of the use of i-JAKs in patients with IIRDs are discussed in detail, namely: dose adjustments due to drug interactions, contraindications, pre-screening, and risk assessment. …”
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Long-term drug use and polypharmacy among the elderly population in the Republic of Srpska, Bosnia and Herzegovina by Marković-Peković Vanda, Škrbić Ranko

“…Elderly patients often take multiple drugs, and it is known that polypharmacy may lead to drug interactions and adverse events. The aim of this study was to analyze the long-term drug use and the prevalence of polypharmacy among the elderly population in the Republic of Srpska, Bosnia and Herzegovina. …”
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Prevention of Protease-Induced Degradation of Desmoplakin via Small Molecule Binding by Isabel M. Romov, Roujon A. Nowzari, Clay P. Page, Madeleine R. Benes, Maegen A. Borzok, Nathan T. Wright

“…Computational screenings did not predict which molecules would protect DSP, likely due to a lack of specific DSP–drug interactions. Molecular dynamic simulations of DSP–drug complexes suggest that some long hydrophobic molecules can bind in a shallow hydrophobic groove that runs alongside the protease cleavage site. …”
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The Effect of a Blended Learning with the Simultaneous Presence of a Clinical Specialist and a Pharmacist on the Learning Rate of Medical Students in the Heart Department of Birja... by Shima Jafari, Yahya Mohammadi, Fatemeh Mehdizadeh, Tooba Kazemi

“…There was a discussion about how to prescribe drugs, their side effects, and drug interactions. To evaluate the course, a test before and after the course was conducted to check their learning level. …”
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Old Age Bipolar Disorder—Epidemiology, Aetiology and Treatment by Ivan Arnold, Julia Dehning, Anna Grunze, Armand Hausmann

“…With constant monitoring and awareness of the possible toxic drug interactions, lithium is a safe drug for OABD patients, both in mania and maintenance. …”
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Dopamine Receptor Partial Agonists: Do They Differ in Their Clinical Efficacy? by Pavel Mohr, Pavel Mohr, Jirí Masopust, Miloslav Kopeček, Miloslav Kopeček

“…Although they share a similar mechanism of action, DRPAs differ in their pharmacodynamics, pharmacokinetics, drug interactions, or safety and tolerability. The antipsychotic efficacy of all three drugs was established in several placebo-controlled randomized trials (RCTs) in schizophrenia, both acute phase and relapse prevention. …”
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