Showing 361 - 380 results of 2,974 for search '"drug interaction"', query time: 0.23s Refine Results
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    Comparing the applications of machine learning, PBPK, and population pharmacokinetic models in pharmacokinetic drug–drug interaction prediction by Jaidip Gill, Marie Moullet, Anton Martinsson, Filip Miljković, Beth Williamson, Rosalinda H. Arends, Venkatesh Pilla Reddy

    Published 2022-12-01
    “…Abstract The gold‐standard approach for modeling pharmacokinetic mediated drug–drug interactions is the use of physiologically‐based pharmacokinetic modeling and population pharmacokinetics. …”
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    Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. by Holly Matthews, Jon Deakin, May Rajab, Maryam Idris-Usman, Niroshini J Nirmalan

    Published 2017-01-01
    “…We report here the use of the optimised Chou Talalay method to define synergistic antimalarial drug interactivity between emetine dihydrochloride hydrate and atovaquone. …”
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    Warfarin therapy in patients with coronary heart disease and atrial fibrillation: drug interactions and genetic sensitivity to warfarin by O. A. Panibratiuk, O. А. Yakovleva

    Published 2020-06-01
    “…Particular emphasis was placed on drug interaction in the standardized treatment of patients with coronary heart disease and atrial fibrillation. …”
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    Physiologically‐based pharmacokinetic modeling of the drug–drug interaction between ivacaftor and lefamulin in cystic fibrosis patients by Magali Amiel, Alice Ke, Steven P. Gelone, Hannah M. Jones, Wolfgang Wicha

    Published 2024-04-01
    “…Lefamulin is a moderate CYP3A inhibitor and co‐administration with ivacaftor may result in a drug–drug interaction (DDI). A CF population was built based on literature using the Simcyp Simulator. …”
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    Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers by Ioana Todor, Adina Popa, Maria Neag, Dana Muntean, Corina Bocsan, Anca Buzoianu, Laurian Vlase, Ana-Maria Gheldiu, Corina Briciu

    Published 2016-06-01
    “…Additional studies are required in order to evaluate the clinical relevance of this pharmacokinetic drug interaction. This article is open to POST-PUBLICATION REVIEW. …”
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